> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/nvx-cov2373-2901ba7e-dc7f-462d-b887-27f753b25c9a
> Record changed: 2026-10-13

# NVX-COV2373

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5095387)

Drug type

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/UK9AK2IN1P)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5095387)

## Names and chemistry

**Drug type**

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/UK9AK2IN1P)

**Drug name**

NVX-COV2373

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5095387)

### Other names (13)

- covovax vaccine protein antigen
- Covovax vaccine protein antigen
- nvx cov 2372
- nvx cov2373
- Nvx-cov 2372
- Nvx-cov2373
- NVX-Cov2373
- NVX-CoV2373
- NVX-CoV2373 (5μg)
- sars cov 2 spike glycoprotein vaccine antigen nvx cov2373
- SARS-COV-2 SPIKE GLYCOPROTEIN VACCINE ANTIGEN NVX-COV2373
- tak 019
- TAK-019

## Identifiers

**CAS registry numbers**

- 2972498-09-0

**ChEMBL ID**

CHEMBL5095387

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5095387)

**RxNorm IDs (RxCUI)**

- 2606073

**FDA ingredient codes (UNII)**

- UK9AK2IN1P

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (2)

- **Condition**  
Severe Acute Respiratory Syndrome

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000694

**Subject identifier**  
D045169
- **Condition**  
Severe Acute Respiratory Syndrome

**Highest recorded phase**  
3

**Condition identifier**  
MONDO:0100096

**Subject identifier**  
D045169

### Open Targets indications (3)

- **Condition identifier**  
EFO\_0000694

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0100096

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0100096

**Highest recorded phase**  
3

### Trial references (8)

- NCT04712110  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04712110)
- NCT05112848  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05112848)
- NCT05249816  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05249816)
- NCT05299359  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05299359)
- NCT05372588  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05372588)
- NCT05463068  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05463068)
- NCT05775887  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05775887)
- NCT05875701  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05875701)

## Chemical properties

**Prodrug**

No

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (11)

- A FIRST IN HUMAN TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF SARS-CoV-2 UQSC2 VACCINE IN HEALTHY ADULTS.
- A proof-of Concept, Randomized 3-month Study to Evaluate the Effects of Three Contraceptive Intrauterine Systems Delivering Copper and a Daily Dose of 5, 20 or 40 μg of Ulipristal Acetate (UPA)
- A Single Heterologous Booster Vaccination Study of TAK-019 in Healthy Japanese Adults (COVID-19)
- A Study of TAK-019 in Healthy Japanese Adults (COVID-19)
- [A Study to Evaluate Safety and Immunogenicity of a COVID-19 Vaccine in People Living With HIV at Risk for SARS-CoV-2 (COVID-19)](https://trialight.com/data/trial/a-study-to-evaluate-safety-and-immunogenicity-of-a-covid-19-10d09ec5-bf39-4f33-936a-e3705fa4138b.md)
- COVID-19 Vaccines Safety Tracking (CoVaST)
- [Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines](https://trialight.com/data/trial/phase-2-3-heterologous-boosting-study-with-different-dose-11366f7d-0e56-4e5c-ad7c-d51c224636f4.md)
- [Phase 3 Boosting Study for the SARS-CoV-2 rS Vaccine](https://trialight.com/data/trial/phase-3-boosting-study-for-the-sars-cov-2-rs-vaccine-f06f7afd-5bf8-4616-b26d-b0342e9bf744.md)
- [Phase 3 Boosting Study for the SARS-CoV-2 rS Variant Vaccines](https://trialight.com/data/trial/phase-3-boosting-study-for-the-sars-cov-2-rs-variant-dac495d3-16b5-4baa-aba4-2d5880a27481.md)
- Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines
- Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults

### In development for (2)

- [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3
- [Severe acute respiratory syndrome](https://trialight.com/data/condition/severe-acute-respiratory-syndrome-7654d02a-f750-52a0-bec2-afe3b4b3c224.md) Phase 3

---

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