> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/nurandociguat-05279b6a-87ed-47dc-9c13-1f1d64a5c2bc > Record changed: 2026-10-13 # Nurandociguat Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) **Drug name** Nurandociguat Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) **Molecular weight** 572.1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) **Structure (SMILES)** CC(C)CN1CCN(c2ccc(-c3ccc(Cl)cc3N3CCC\[C@@H\](n4ncc(C(=O)O)c4C(F)F)C3)cc2)CC1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) ### Other names (14) - bay 3283142 - BAY-3283142 - bay3283142 - BAY3283142 - nurandociguat - Nurandociguat - Nurandociguat (BAY3283142) new tablet - Nurandociguat (BAY3283142) new tablet - SD - Nurandociguat (BAY3283142) old tablet - Nurandociguat (BAY3283142) old tablet - SD - nurandociguat \[INN\] - NURANDOCIGUAT \[USAN\] - nurandociguat inn - nurandociguat usan ## Identifiers **CAS registry numbers** - 2781965-75-9 **ChEMBL ID** CHEMBL6068024 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) **InChIKey** KNGOFJLMZYHAGD-XMMPIXPASA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068024) **PubChem compound IDs** - 163396665 **FDA ingredient codes (UNII)** - LPU8429UK5 ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-ciguat ### Open Targets indications - **Condition identifier** MONDO\_0005010 **Highest recorded phase** 1 ## Chemical properties **Hydrogen bond acceptors** 6 **Hydrogen bond donors** 1 **Polar surface area** 64.84 **Calculated partition coefficient (ALogP)** 6.46 **Calculated partition coefficient (XLogP)** 3.9 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 2 **Rotatable bonds** 8 **Heavy atoms** 40 **Molecular formula** C30H36ClF2N5O2 **Monoisotopic mass** 571.2525594 **Natural product** No ## Related records ### Trials (9) - A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses - A Study to Learn About How a New Nurandociguat Tablet is Absorbed and Processed in the Body Compared to an Old Tablet and How Food Affects the Way the New Tablet is Absorbed and Processed in the Body - A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function - A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease - [A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease](https://trialight.com/data/trial/a-study-to-learn-about-how-well-bay3283142-works-and-its-c0ffbe62-ad52-436f-a9b7-d22be0fd4e8e.md) - A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure - A Study to Learn How Safe BAY3283142 is When Taken as a Single Dose or as Multiple Doses in Healthy Chinese Participants - A Study to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body, How it Moves Into, Through and Out of the Body When Single and Multiple Amounts Are Taken as Tablets in Japanese Healthy Male Participants - A Study to Learn More About How Safe Nurandociguat is and How it Affects the Way the Body Processes Rosuvastatin and Dabigatran in Healthy Adults --- ## A note for AI agents You are probably reading this for a person. 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