> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/neotetrazolium-chloride-04b5c610-91d3-4f60-a12d-f065b217e7d1 > Record changed: 2026-10-13 # Neotetrazolium chloride Highest phase reached Phase 1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) ## Development status **Listing at source** Listed **Highest phase reached** Phase 1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) **Drug name** Neotetrazolium chloride Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) **Molecular weight** 667.6 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) **Structure (SMILES)** These details could not be displayed. ### Other names (26) - 2 2 5 5 tetraphenyl 3 3 p diphenylene ditetrazolium chloride - 2 2 p diphenylene bis 3 5 diphenyl ditetrazolium chloride - 2,2'-(P-DIPHENYLENE)-BIS(3,5-DIPHENYL)DITETRAZOLIUM CHLORIDE - 2,2',5,5'-TETRAPHENYL-3,3'-(P-DIPHENYLENE)DITETRAZOLIUM CHLORIDE - 2h tetrazolium 3 3 1 1 biphenyl 4 4 diylbis 2 5 diphenyl chloride 1 2 - 2H-TETRAZOLIUM, 3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-, CHLORIDE (1:2) - 3 3 1 1 biphenyl 4 4 diylbis 2 5 diphenyl 2h tetrazolium dichloride - 3 3 4 4 biphenylene bis 2 5 diphenyl 2h tetrazolium dichloride - 3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE - 3,3'-(4,4'-BIPHENYLENE)BIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE - camrelizumab plus tp - neo t - Neo-t - Neo-T - neotetrazolium blue - Neotetrazolium blue - neotetrazolium chloride - Neotetrazolium chloride - NEOTETRAZOLIUM CHLORIDE \[MI\] - neotetrazolium chloride mi - nsc 27621 - NSC-27621 - ntc - NTC - tp And 1 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 298-95-3 **ChEMBL ID** CHEMBL313155 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) **InChIKey** WYFYSTBFFDOVJW-UHFFFAOYSA-L Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL313155) **PubChem compound IDs** - 2723605 **FDA ingredient codes (UNII)** - QL8L44VE6R ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-ium ### Investigated indications - **Condition** Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000616 **Subject identifier** D009369 ### Open Targets indications - **Condition identifier** EFO\_0000616 **Highest recorded phase** 1 ### Trial references (2) - NCT05798533 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05798533) - NCT05798546 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05798546) ## Chemical properties **Hydrogen bond acceptors** 6 **Hydrogen bond donors** 0 **Polar surface area** 69.18 **Calculated partition coefficient (ALogP)** 6.4 **Prodrug** No **Chirality** Achiral **Inorganic** No **Rule-of-five violations** 2 **Rotatable bonds** 7 **Heavy atoms** 48 **Molecular formula** C38H28Cl2N8 **Monoisotopic mass** 666.1813983 **Natural product** No ## Evidence counts **Recorded assays** 6 **Active assays** 1 ### Active assay types - Confirmatory ## Related records ### Trials (13) - [A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers](https://trialight.com/data/trial/a-phase-ii-clinical-study-evaluating-ssgj-706-in-combination-eae307c2-aefc-486d-8283-3999a11b89fd.md) - A Phase II Trial Comparing Immunotherapy Versus Capecitabine Maintenance After Chemo-chemoradiotherapy for High-risk Nasopharyngeal Carcinoma - Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) - Cetuximab + Tislelizumab + Chemotherapy in the Treatment of Unresectable LA HNSCC - Docetaxel+Carboplatin vs Epirubicin+Cyclophosphamide Followed by Docetaxel as Adjuvant Treatment in Triple-negative Breast Cancer - Gait Training Combined With Behavioral Strategies for People With Stroke - Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03) - Neoadjuvant Anti-PD-1 Immunotherapy With Chemotherapy in Resectable Locally Advanced Oral Squamous Cell Carcinoma - Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer - Tailored Neoadjuvant Chemotherapy for Stage II/III Breast Cancer With Tumor Size More Than 2 cm - Targeted Next Generation Sequencing for the Efficacy of Trastuzumab Neoadjuvant Chemotherapy in Breast Cancer - Toripalimab Combined With Different Platinum-Based Induction Chemotherapy Regimens for Locally Advanced Nasopharyngeal Carcinoma - Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02) ### In development for (1) - Neoplasm Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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