> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/neisseria-meningitidis-outer-membrane-vesicles-0ba0d9d0-51ae-4b24-b31b-350946a8ca94 > Record changed: 2026-11-04 # Neisseria meningitidis outer membrane vesicles Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) First approval year 2013 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) ## Development status **First approval year** 2013 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) **Drug name** Neisseria meningitidis outer membrane vesicles Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) ### Brand names (2) - neisseria meningitidis outer membrane vesicles component of bexsero - Neisseria meningitidis outer membrane vesicles component of bexsero ### Other names (2) - neisseria meningitidis outer membrane vesicles - Neisseria meningitidis outer membrane vesicles ## Identifiers **ChEMBL ID** CHEMBL6068370 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068370) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Mechanisms of action - **Mechanism** Outer membrane vesicles vaccine antigen **Action type** VACCINE\_ANTIGEN **Target** Outer membrane vesicles ### Investigated indications (2) - **Condition** Vaccination **Highest recorded phase** 4 **Condition identifier** EFO:0004292 **Subject identifier** D014611 - **Condition** Meningitis, Meningococcal **Highest recorded phase** 4 **Condition identifier** EFO:1001040 **Subject identifier** D008585 ### Open Targets indications (3) - **Condition identifier** EFO\_0004249 - **Condition identifier** EFO\_1001040 - **Condition identifier** MONDO\_0005373 **Highest recorded phase** 4 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (43) - A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old) - A Phase 3b Study to Assess the Safety of Novartis Meningococcal B Recombinant Vaccine When Administered in Healthy At-risk Adults - A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Children Aged 2 to 10 Years - A Phase 3b, Single-Center, Open-label Study to Assess the Immunogenicity and Safety of Novartis Meningococcal B Recombinant Vaccine When Administered at a 0, 2-Month Schedule in Healthy At-Risk Adults Aged 18 to 65 Years Inclusive. - A Sourcing Study to Collect Human Blood Samples From Healthy Adults - A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age - Assessment of Antibody Persistence at Eighteen Months After the Completion of the Vaccination Course in Study V72P10 - Baby Vaccine Study (Sched3) - Combined Study - Phase 3b MenB Long Term Persistence in Adolescents - Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults - Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae - Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population - Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of a Booster Dose of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received Three Doses of the Same Vaccine - Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of Booster Doses of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received One or Four Doses of the Same Vaccine - Extension Study of V72P13 to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered as a Booster or as a Two-dose Catch-up to Healthy Toddlers - Immunogenicity and Reactogenicity of a Meningococcal B Outer Membrane Vesicle Vaccine Given in a 0,6,12 Month Schedule to Health UK Adults - Immunogenicity and Safety of MenB Vaccine in Pediatric Patients With Autoimmune Rheumatic Diseases - Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine - Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination - Novartis Vaccine and Diagnostics Carriage Trial ### Approved for (2) - [Meningococcal infection](https://trialight.com/data/condition/meningococcal-infection-127e031a-0256-5064-a935-b84efd154e0d.md) - [Meningococcal meningitis](https://trialight.com/data/condition/meningococcal-meningitis-986c81ca-25d6-5c71-bad2-6d638b296341.md) --- ## A note for AI agents You are probably reading this for a person. 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