> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/neisseria-meningitidis-factor-h-binding-protein-c4d3ae7d-0b84-4518-8625-03306c59aa10 > Record changed: 2026-10-13 # Neisseria meningitidis factor H binding protein Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) First approval year 2013 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) ## Development status **First approval year** 2013 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) **Drug name** Neisseria meningitidis factor H binding protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) ### Brand names (8) - neisseria meningitidis factor h binding protein component of bexsero - Neisseria meningitidis factor h binding protein component of bexsero - neisseria meningitidis group b recombinant lp2086 a05 protein variant antigen component of penbraya - Neisseria meningitidis group b recombinant lp2086 a05 protein variant antigen component of penbraya - neisseria meningitidis group b recombinant lp2086 b01 protein variant antigen component of penbraya - Neisseria meningitidis group b recombinant lp2086 b01 protein variant antigen component of penbraya - trumenba - Trumenba ### Other names (10) - Meningococcal Group B vaccine (Trumenba®) - meningococcal group b vaccine trumenba - neisseria meningitidis factor h binding protein - Neisseria meningitidis factor h binding protein - neisseria meningitidis group b recombinant lp2086 a05 protein variant antigen - Neisseria meningitidis group b recombinant lp2086 a05 protein variant antigen - neisseria meningitidis group b recombinant lp2086 b01 protein variant antigen - Neisseria meningitidis group b recombinant lp2086 b01 protein variant antigen - Trumenba - Trumenba® ## Identifiers **ChEMBL ID** CHEMBL6068499 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068499) ## Regulatory information ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** Yes **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No ## Pharmacology ### Mechanisms of action - **Mechanism** Factor H binding protein vaccine antigen **Action type** VACCINE\_ANTIGEN **Target** Factor H binding protein **Protein identifier** Q9JXV4 ### Open Targets mechanisms - **Mechanism** Factor H binding protein vaccine antigen **Action type** VACCINE ANTIGEN **Target** Factor H binding protein ### Investigated indications (3) - **Condition** Meningitis **Highest recorded phase** 4 **Condition identifier** EFO:0000584 **Subject identifier** D008581 - **Condition** Vaccination **Highest recorded phase** 4 **Condition identifier** EFO:0004292 **Subject identifier** D014611 - **Condition** Meningitis, Meningococcal **Highest recorded phase** 4 **Condition identifier** EFO:1001040 **Subject identifier** D008585 ### Open Targets indications (7) - **Condition identifier** EFO\_0000584 - **Condition identifier** EFO\_0004249 - **Condition identifier** EFO\_1001040 - **Condition identifier** MONDO\_0004796 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005373 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0021108 - **Condition identifier** MONDO\_0021108 **Highest recorded phase** 4 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (18) - A Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States. - Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae - Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom - Investigating the Immunogenicity of a U.S.-Licensed Meningococcal Serogroup B Vaccine (Trumenba) - MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age - MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults - Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination - Research Trial Assessing the Immunogenicity and Safety of Three Meningococcal B Vaccine Strategies Among Patients With Asplenia. - Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection - [Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants](https://trialight.com/data/trial/safety-and-immunogenicity-of-an-investigational-pentavalent-3cee0ccc-93dd-4cb8-81bc-79346e396af8.md) - Safety and Immunogenicity of GlaxoSmithKline Biologicals Meningococcal Group B Vaccine When Administered Concomitantly With GlaxoSmithKline Biologicals MenACWY Conjugate Vaccine to Healthy Infants - Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy Infants - Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants - [Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents](https://trialight.com/data/trial/study-of-an-investigational-pentavalent-meningococcal-abcyw-61f873fd-243b-489f-9f49-1dc6270c7e44.md) - Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccine - Study to Assess the Safety and Immunogenicity of GSK Meningococcal Group B Vaccine When Administered Concomitantly With GSK Meningococcal MenACWY Conjugate Vaccine in Healthy Subjects of 16-18 Years of Age - Study to Evaluate the Immune Response After a Booster Dose of a Quadrivalent Meningococcal (MenACYW) Conjugate Vaccine When Administered Alone or Concomitantly With a Licensed Meningococcal Serogroup B Vaccine, in Participants Who Received Primary Quadrivalent Meningococcal Conjugate Vaccine (MCV4) - Trial to Describe the Safety, Tolerability, and Immunogenicity of Trumenba When Administered to Immunocompromised Participants ≥10 Years of Age ### Approved for (2) - Infectious meningitis - [Meningococcal meningitis](https://trialight.com/data/condition/meningococcal-meningitis-986c81ca-25d6-5c71-bad2-6d638b296341.md) ### Other linked conditions (2) - Meningitis - [Meningococcal infection](https://trialight.com/data/condition/meningococcal-infection-127e031a-0256-5064-a935-b84efd154e0d.md) --- ## A note for AI agents You are probably reading this for a person. 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