> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/naproxen-f8832358-74f9-4a7d-ac13-bc9bb9f4661b > Record changed: 2026-10-29 # Naproxen Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) First approval year 1976 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) ## Development status **First approval year** 1976 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **Drug name** Naproxen Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **Molecular weight** 230.26 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **Structure (SMILES)** COc1ccc2cc(\[C@H\](C)C(=O)O)ccc2c1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) ### Brand names (54) - arthrosin 250 - Arthrosin 250 - arthrosin 250 ec - Arthrosin 250 ec - arthrosin 500 - Arthrosin 500 - arthrosin 500 ec - Arthrosin 500 ec - condrotec - Condrotec - ec naprosyn - Ec-naprosyn - feminax ultra - Feminax ultra - grenoxal - Grenoxal - kenosyn - Kenosyn - laraflex - Laraflex - napratec op - Napratec op - naprosyn - Naprosyn - naprosyn 375 And 29 more, listed on the interactive page. ### Other names (51) - 2 naphthaleneacetic acid 6 methoxy alpha methyl s - 2-NAPHTHALENEACETIC ACID, 6-METHOXY-.ALPHA.-METHYL-, (S)- - naprosyn - Naprosyn - naprosyn 500 mg - Naprosyn 500 mg - Naprosyn® - naproxen - Naproxen - NAPROXEN \[EP MONOGRAPH\] - NAPROXEN \[GREEN BOOK\] - NAPROXEN \[HSDB\] - naproxen \[INN\] - NAPROXEN \[JAN\] - NAPROXEN \[MART.\] - NAPROXEN \[MI\] - NAPROXEN \[ORANGE BOOK\] - NAPROXEN \[USAN\] - NAPROXEN \[USP MONOGRAPH\] - NAPROXEN \[USP-RS\] - NAPROXEN \[VANDF\] - Naproxen \[WHO-DD\] - naproxen component of pn400 - NAPROXEN COMPONENT OF PN400 - naproxen ep monograph And 26 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 22204-53-1 **ChEMBL ID** CHEMBL154 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **InChIKey** CMWTZPSULFXXJA-VIFPVBQESA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) **PubChem compound IDs** - 156391 **RxNorm IDs (RxCUI)** - 7258 **FDA ingredient codes (UNII)** - 57Y76R9ATQ ### ATC classification codes (3) - G02CC02 - M01AE02 - M02AA12 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL154) ## Regulatory information ### United States **Applicant** ATNAHS PHARMA US **Approval date** 23 Mar 1987 **Application number** NDA018965 ### Other regulatory facts **First in class** No **Orphan designation** No **Availability** Over the counter **Boxed warning** Yes ## Pharmacology ### Drug classification **Pharmacology name** naproxen **Type** Synthetic organic **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (4) - **Action** Inhibition **Action type** Inhibitor **Target** COX-1 **Gene symbol** PTGS1 **Protein identifier** P23219 **Median affinity** 5.49 **Affinity units** pIC50 **Primary target** Yes - **Action** Inhibition **Action type** Inhibitor **Target** COX-2 **Gene symbol** PTGS2 **Protein identifier** P35354 **Median affinity** 5.6 **Affinity units** pIC50 **Primary target** Yes - **Mechanism** Cyclooxygenase inhibitor **Action type** Inhibitor **Target** Cyclooxygenase **Protein identifier** P23219 - **Mechanism** Cyclooxygenase inhibitor **Action type** Inhibitor **Target** Cyclooxygenase **Protein identifier** P35354 ### Open Targets mechanisms - **Mechanism** Cyclooxygenase inhibitor **Action type** Inhibitor **Target** Cyclooxygenase ### DrugCentral mechanisms (2) - **Action type** Inhibitor **Gene symbol** PTGS1 **Protein identifier** P23219 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PTGS2 **Protein identifier** P35354 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (41) - **Condition** Wounds and Injuries **Highest recorded phase** 2 **Condition identifier** EFO:0000546 **Subject identifier** D014947 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Arthritis, Rheumatoid **Highest recorded phase** 4 **Condition identifier** EFO:0000685 **Subject identifier** D001172 - **Condition** Arthritis, Juvenile **Highest recorded phase** 4 **Condition identifier** EFO:0002609 **Subject identifier** D001171 - **Condition** Pain **Highest recorded phase** 4 **Condition identifier** EFO:0003843 **Subject identifier** D010146 - **Condition** Acute Pain **Highest recorded phase** 4 **Condition identifier** EFO:0003843 **Subject identifier** D059787 - **Condition** Spondylitis, Ankylosing **Highest recorded phase** 4 **Condition identifier** EFO:0003898 **Subject identifier** D013167 - **Condition** Gout **Highest recorded phase** 4 **Condition identifier** EFO:0004274 **Subject identifier** D006073 - **Condition** Arthritis, Gouty **Highest recorded phase** 4 **Condition identifier** EFO:0004274 **Subject identifier** D015210 - **Condition** Duodenal Ulcer **Highest recorded phase** 2 **Condition identifier** EFO:0004607 **Subject identifier** D004381 - **Condition** Osteoarthritis, Knee **Highest recorded phase** 3 **Condition identifier** EFO:0004616 **Subject identifier** D020370 - **Condition** Rheumatic Diseases **Highest recorded phase** 4 **Condition identifier** EFO:0005755 **Subject identifier** D012216 - **Condition** Vaginitis **Highest recorded phase** 4 **Condition identifier** EFO:0005757 **Subject identifier** D014627 - **Condition** Neuralgia **Highest recorded phase** 2 **Condition identifier** EFO:0005762 **Subject identifier** D009437 - **Condition** Arthritis **Highest recorded phase** 4 **Condition identifier** EFO:0005856 **Subject identifier** D001168 - **Condition** Common Cold **Highest recorded phase** 4 **Condition identifier** EFO:0007214 **Subject identifier** D003139 - **Condition** Stomach Ulcer **Highest recorded phase** 4 **Condition identifier** EFO:0009454 **Subject identifier** D013276 - **Condition** Pleural Effusion **Highest recorded phase** 2 **Condition identifier** EFO:0009637 **Subject identifier** D010996 - **Condition** Muscle Cramp **Highest recorded phase** 4 **Condition identifier** EFO:0009846 **Subject identifier** D009120 - **Condition** Toothache **Highest recorded phase** 4 **Condition identifier** EFO:0010072 **Subject identifier** D014098 - **Condition** Osteoarthritis, Hip **Highest recorded phase** 3 **Condition identifier** EFO:1000786 **Subject identifier** D015207 - **Condition** Fever **Highest recorded phase** 4 **Condition identifier** HP:0001945 **Subject identifier** D005334 - **Condition** Headache **Highest recorded phase** 4 **Condition identifier** HP:0002315 **Subject identifier** D006261 - **Condition** Arthralgia **Highest recorded phase** 4 **Condition identifier** HP:0002829 **Subject identifier** D018771 - **Condition** Myalgia **Highest recorded phase** 4 **Condition identifier** HP:0003326 **Subject identifier** D063806 And 16 more, listed on the interactive page. ### Open Targets indications (103) - **Condition identifier** EFO\_0000546 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000685 - **Condition identifier** EFO\_0001065 - **Condition identifier** EFO\_0002609 - **Condition identifier** EFO\_0003898 - **Condition identifier** EFO\_0004274 - **Condition identifier** EFO\_0004607 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004616 **Highest recorded phase** 3 - **Condition identifier** EFO\_0005279 **Highest recorded phase** 1 - **Condition identifier** EFO\_0005755 - **Condition identifier** EFO\_0005757 - **Condition identifier** EFO\_0005757 **Highest recorded phase** 4 - **Condition identifier** EFO\_0005762 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005856 - **Condition identifier** EFO\_0007214 - **Condition identifier** EFO\_0009454 - **Condition identifier** EFO\_0009760 - **Condition identifier** EFO\_0009846 - **Condition identifier** EFO\_0009846 **Highest recorded phase** 4 - **Condition identifier** EFO\_0010072 - **Condition identifier** EFO\_0010072 **Highest recorded phase** 4 - **Condition identifier** EFO\_0022861 **Highest recorded phase** 2 - **Condition identifier** EFO\_1001412 **Highest recorded phase** 1 - **Condition identifier** EFO\_1001801 - **Condition identifier** EFO\_1001896 And 78 more, listed on the interactive page. ### Warnings (3) - **Warning** Black Box Warning **Effect** cardiotoxicity - **Warning** Black Box Warning **Effect** gastrointestinal toxicity - **Warning** Black Box Warning **Effect** neurotoxicity ### Open Targets warnings (3) - **Warning** Black Box Warning **Effect** cardiotoxicity **Country** United States - **Warning** Black Box Warning **Effect** gastrointestinal toxicity **Country** United States - **Warning** Black Box Warning **Effect** neurotoxicity **Country** United States ### Reported adverse events (69) - **Event** abdominal discomfort **Reports** 440 **Reporting signal score** 431.818 - **Event** abdominal pain **Reports** 437 **Reporting signal score** 165.523 - **Event** abdominal pain upper **Reports** 414 **Reporting signal score** 286.673 - **Event** acne cystic **Reports** 44 **Reporting signal score** 141.273 - **Event** acute kidney injury **Reports** 502 **Reporting signal score** 362.433 - **Event** adrenal insufficiency **Reports** 130 **Reporting signal score** 223.182 - **Event** angioedema **Reports** 219 **Reporting signal score** 159.11 - **Event** arthralgia **Reports** 646 **Reporting signal score** 279.219 - **Event** arthropathy **Reports** 414 **Reporting signal score** 648.131 - **Event** body height below normal **Reports** 83 **Reporting signal score** 317.383 - **Event** bone density decreased **Reports** 81 **Reporting signal score** 148.835 - **Event** c-reactive protein abnormal **Reports** 211 **Reporting signal score** 622.23 - **Event** c-reactive protein increased **Reports** 204 **Reporting signal score** 215.696 - **Event** condition aggravated **Reports** 592 **Reporting signal score** 308.437 - **Event** deafness transitory **Reports** 100 **Reporting signal score** 402.581 - **Event** disability **Reports** 87 **Reporting signal score** 170.874 - **Event** dizziness **Reports** 690 **Reporting signal score** 210.906 - **Event** drug hypersensitivity **Reports** 977 **Reporting signal score** 863.487 - **Event** drug intolerance **Reports** 538 **Reporting signal score** 597.014 - **Event** duodenal ulcer **Reports** 165 **Reporting signal score** 349.214 - **Event** duodenal ulcer haemorrhage **Reports** 94 **Reporting signal score** 239.107 - **Event** duodenal ulcer perforation **Reports** 86 **Reporting signal score** 213.678 - **Event** ear infection **Reports** 166 **Reporting signal score** 257.062 - **Event** faeces discoloured **Reports** 133 **Reporting signal score** 189.271 - **Event** femur fracture **Reports** 170 **Reporting signal score** 211.69 And 44 more, listed on the interactive page. ### Trial references (96) - NCT00004845 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004845) - NCT00034853 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00034853) - NCT00279747 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00279747) - NCT00652925 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00652925) - NCT00807846 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00807846) - NCT01358383 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01358383) - NCT01544114 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01544114) - NCT00157872 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00157872) - NCT00346216 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00346216) - NCT00626275 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00626275) - NCT00650455 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00650455) - NCT00959439 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00959439) - NCT02451748 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02451748) - NCT00175032 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00175032) - NCT00367211 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00367211) - NCT00392080 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00392080) - NCT00418782 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00418782) - NCT00435292 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00435292) - NCT00504127 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00504127) - NCT00542555 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00542555) - NCT00648258 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00648258) - NCT00652808 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00652808) - NCT00664560 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00664560) - NCT00665431 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00665431) - NCT00665743 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00665743) And 71 more, listed on the interactive page. ## Dosing **Dose** 1 capsule **How often** Every 8 to 12 hours ### Conditions of use (5) - Do not exceed 2 capsules in any 8 to 12-hour period - Do not exceed 3 capsules in 24 hours - Drink a full glass of water with each dose - For the first dose, you may take 2 capsules within the first hour - If taken with food, it may take longer to work ## Chemical properties **Hydrogen bond acceptors** 2 **Hydrogen bond donors** 1 **Polar surface area** 46.53 **Calculated partition coefficient (ALogP)** 3.04 **Calculated partition coefficient (XLogP)** 3.3 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 3 **Heavy atoms** 17 **Molecular formula** C14H14O3 **Monoisotopic mass** 230.094294304 **Natural product** Yes ## National Drug Codes - 0054-3630 - 0615-8094 - 11534-211 - 11534-212 - 25000-138 - 25000-139 - 25000-140 - 27241-202 - 27241-203 - 31722-682 - 42192-619 - 42494-453 - 42494-454 - 42708-043 - 42708-140 - 43063-600 - 43063-650 - 43063-920 - 43353-211 - 43353-216 - 43353-218 - 45865-238 - 49483-617 - 49483-618 - 49483-619 And 169 more, listed on the interactive page. ## Evidence counts **Recorded assays** 5,015 **Active assays** 57 ### Active assay types (3) - Confirmatory - Other - Summary ## Pharmacologic actions - Anti-Inflammatory Agents, Non-Steroidal Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000894.html) - Gout Suppressants Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D006074.html) - Cyclooxygenase Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D016861.html) ## Biological measurements ### Observed measurements #### Distribution coefficient (LogD) **Median** 1.09 **Mean** 1.42 **Minimum** 0.2 **Maximum** 3.3 **Unit** unitless **Assays** 4 **Standard deviation** 1.32232 **Summary method** median **Censored results excluded** 0 **Other units excluded** 0 **Unknown units excluded** 0 #### Measurement types - LogD #### Solubility **Median** 20,860 **Mean** 21,156 **Minimum** 3,580 **Maximum** 40,930 **Unit** ug/mL **Assays** 20 **Standard deviation** 12,066 **Summary method** median **Censored results excluded** 0 **Other units excluded** 0 **Unknown units excluded** 0 #### Measurement types - Solubility #### Oral bioavailability **Median** 100 **Mean** 100 **Minimum** 100 **Maximum** 100 **Unit** % **Assays** 1 **Standard deviation** 0 **Summary method** median **Censored results excluded** 0 **Other units excluded** 0 **Unknown units excluded** 0 #### Measurement types - F ## Related records ### Trials (197) - A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee - A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs. - A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin - A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In Taiwan - A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study) - A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis - A One Year Double-blind Trial to Investigate the Efficacy and Safety of Meloxicam Oral Suspension in Juvenile Rheumatoid Arthritis (JRA/JIA) - A Pharmacokinetic (PK) Study Evaluating Naproxen and Esomeprazole Plasma Levels - A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome - A Proof-of-Concept Study Assessing NEO6860 in Osteoarthritis Pain - A Randomized Controlled Trial of Oral Naproxen and Transdermal Estradiol for Bleeding in LNG-IUC - A Randomized Study of Three Medication Regimens for Acute Low Back Pain - A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or Knee - A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach - A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee - A Study of Tanezumab in Adults With Chronic Low Back Pain - A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain - A Study Of The Effect Of CJ-023,423 On The Incidence Of Stomach Ulcers - A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee - A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The Thumb ### Approved for (14) - [Ankylosing spondylitis](https://trialight.com/data/condition/ankylosing-spondylitis-9b1fe73f-f462-5baf-85b0-5cbf33725458.md) - [Arthritic joint disease](https://trialight.com/data/condition/arthritic-joint-disease-594ede40-773b-5c20-afc1-eb18dabbe039.md) - Bursitis - Common cold - Dysmenorrhea - Gastric ulcer - [Gout](https://trialight.com/data/condition/gout-b61aaf55-4a3b-56d9-966a-ca77100d2fc5.md) - Juvenile idiopathic arthritis - [Osteoarthritis](https://trialight.com/data/condition/osteoarthritis-e8c428fb-1597-576d-bcf0-f3b27ebc6a00.md) - [Rheumatic disorder](https://trialight.com/data/condition/rheumatic-disorder-e863530e-2c28-5a33-b1be-d12fa4d746b9.md) - [Rheumatoid arthritis](https://trialight.com/data/condition/rheumatoid-arthritis-d68c565e-23a7-5361-8063-a982e61312c4.md) - Spondylitis - Tendinitis - Vaginitis ### In development for (17) - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 2 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - Duodenal ulcer Phase 2 - Injury Phase 2 - Lynch syndrome Phase 1 - [Migraine disorder](https://trialight.com/data/condition/migraine-disorder-0a28e77d-6415-5582-980f-2d0721f95f76.md) Phase 3 - [Multiple sclerosis](https://trialight.com/data/condition/multiple-sclerosis-62806c95-fe1b-529e-bd16-95cb92d15375.md) Phase 3 - Neuralgia Phase 2 - Osteoarthritis, hip Phase 3 - [Osteoarthritis, knee](https://trialight.com/data/condition/osteoarthritis-knee-217c801b-d59c-514b-92dd-3abbf23b24d7.md) Phase 3 - Peptic ulcer disease Phase 3 - [Prostate adenocarcinoma](https://trialight.com/data/condition/prostate-adenocarcinoma-84e3e3af-1ae1-5760-8157-8d9fc0cff608.md) Phase 2 - [Prostate cancer](https://trialight.com/data/condition/prostate-cancer-3659fc70-617b-5868-a093-ae819ffc6755.md) Phase 2 - Temporomandibular joint disorder Phase 1 - Tibial muscular dystrophy Phase 1 - Transient myeloproliferative syndrome Phase 1 ### Other linked conditions (2) - [Endometriosis](https://trialight.com/data/condition/endometriosis-3a5471b6-6d24-50b8-b1e6-8803dd78b0db.md) - [Migraine with aura](https://trialight.com/data/condition/migraine-with-aura-e2c8f3b7-7f7f-5f92-9eee-1fe843c3d45b.md) ### Targets (2) - [PTGS1](https://trialight.com/data/target/ptgs1-5707ce48-8ccd-5bd5-8c18-9c64cacc2fef.md) Cyclooxygenase inhibitor - [PTGS2](https://trialight.com/data/target/ptgs2-85dbd9a5-4609-5423-b863-90d0a825b213.md) Cyclooxygenase inhibitor --- ## A note for AI agents You are probably reading this for a person. 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