> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/molgramostim-7df3df64-2730-4bd4-93be-4cdf7d3d8907
> Record changed: 2026-10-13

# Molgramostim

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

Drug type

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

## Names and chemistry

**Drug type**

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

**Drug name**

Molgramostim

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

### Brand names (2)

- leucomax
- Leucomax

### Other names (43)

- g scf granulocyte colony stimulating factor
- G-SCF (Granulocyte-colony stimulating factor)
- GMCSF (granulocyte macrophage colony stimulating factor)
- granulocyte macrophage colony stimulating factor
- Granulocyte Macrophage Colony Stimulating Factor
- granulocyte macrophage colony stimulating factor molgramostim
- granulocyte macrophage colony stimulating factor molgramostim mi
- Granulocyte Macrophage-colony Stimulating Factor
- GRANULOCYTE MACROPHAGE-COLONY STIMULATING FACTOR
- Granulocyte-macrophage colony stimulating factor
- Granulocyte-macrophage colony-stimulating factor
- Granulocyte-macrophage Colony-stimulating Factor
- Granulocyte-Macrophage Colony-Stimulating Factor
- Granulocyte-macrophage colony-stimulating factor molgramostim
- GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR MOLGRAMOSTIM \[MI\]
- Granulocyte-macrophage colony-stimulating factor subcutaneous injection
- Leucomax
- molgradex
- Molgradex
- molgramostim
- Molgramostim
- Molgramostim (genetical recombination)
- MOLGRAMOSTIM (GENETICAL RECOMBINATION) \[JAN\]
- molgramostim \[INN\]
- MOLGRAMOSTIM \[JAN\]

And 18 more, listed on the interactive page.

## Identifiers

**ATC classification codes**

- L03AA03

Sources for recorded values

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

**CAS registry numbers**

- 99283-10-0

**ChEMBL ID**

CHEMBL2109134

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109134)

**RxNorm IDs (RxCUI)**

- 70161

**FDA ingredient codes (UNII)**

- B321AL142J

## Regulatory information

### Other regulatory facts

**Patents**

0

**Designations**

1

**First in class**

No

**Fast track**

No

**Breakthrough designation**

No

**Orphan designation**

No

**Priority review**

No

**Orphan exclusivity**

No

**Accelerated approval**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-stim; -stim

### Investigated indications (8)

- **Condition**  
Leukemia, Myeloid, Acute

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000222

**Subject identifier**  
D015470
- **Condition**  
Melanoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000389

**Subject identifier**  
D008545
- **Condition**  
Neoplasms

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369
- **Condition**  
Severe Acute Respiratory Syndrome

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000694

**Subject identifier**  
D045169
- **Condition**  
Mycobacterium Infections

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0009429

**Subject identifier**  
D009164
- **Condition**  
Ascites

**Highest recorded phase**  
1

**Condition identifier**  
HP:0001541

**Subject identifier**  
D001201
- **Condition**  
Pulmonary Alveolar Proteinosis

**Highest recorded phase**  
3

**Condition identifier**  
MONDO:0012579

**Subject identifier**  
D011649
- **Condition**  
Severe Acute Respiratory Syndrome

**Highest recorded phase**  
2

**Condition identifier**  
MONDO:0100096

**Subject identifier**  
D045169

### Open Targets indications (82)

- **Condition identifier**  
EFO\_0000180
- **Condition identifier**  
EFO\_0000222

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000389
- **Condition identifier**  
EFO\_0000616
- **Condition identifier**  
EFO\_0000694

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0007456

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0009429

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_1000211

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_1001904

**Highest recorded phase**  
2
- **Condition identifier**  
GO\_0042060

**Highest recorded phase**  
1
- **Condition identifier**  
HP\_0000789
- **Condition identifier**  
HP\_0001541

**Highest recorded phase**  
1
- **Condition identifier**  
HP\_0100806

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0001056

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0001437

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0002974

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004948

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004967

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004986

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004992

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005008

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005012

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005015
- **Condition identifier**  
MONDO\_0005023

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005059

**Highest recorded phase**  
2

And 57 more, listed on the interactive page.

### Reported adverse events (9)

- **Event**  
bone marrow failure

**Reports**  
9

**Reporting signal score**

28.6889
- **Event**  
capillary leak syndrome

**Reports**  
5

**Reporting signal score**

25.3628
- **Event**  
febrile neutropenia

**Reports**  
4

**Reporting signal score**

5.94899
- **Event**  
frostbite

**Reports**  
1

**Reporting signal score**

5.85232
- **Event**  
karyotype analysis abnormal

**Reports**  
1

**Reporting signal score**

6.34931
- **Event**  
low birth weight baby

**Reports**  
3

**Reporting signal score**

9.36628
- **Event**  
mutagenic effect

**Reports**  
1

**Reporting signal score**

7.85289
- **Event**  
pupillary reflex impaired

**Reports**  
2

**Reporting signal score**

8.39556
- **Event**  
sjogren's syndrome

**Reports**  
2

**Reporting signal score**

6.90496

### Trial references (10)

- NCT00880243  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00880243)
- NCT01729663  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01729663)
- NCT02595060  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02595060)
- NCT02702180  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02702180)
- NCT03482752  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03482752)
- NCT04544293  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04544293)
- NCT06431776  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06431776)
- NCT03421743  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03421743)
- NCT04569877  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04569877)
- NCT05501340  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05501340)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (143)

- A Clinical Study of Recombinant Human Vascular Endothelial Inhibitor in Combination With PRaG for Advanced Refractory Non-small Cell Lung Cancer
- A Multicenter RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML Patients
- A Phase 2 Trial of Filanesib in Relapsed/Refractory Multiple Myeloma (AfFIRM)
- A Pilot Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Generalized Myasthenia Gravis
- A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)
- A Prospective Study of Combination of Peginterferon Alfa-2b (40kD, Y-shape) and GM-CSF in Chronic Hepatitis B
- A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.
- A Randomized Study of the Site for Growth Factor Injection for Patients Undergoing Autologous Stem Cell Transplantation
- A Study of ARRY-520 and Bortezomib Plus Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma
- A Study of ARRY-520 in Patients With Advanced Cancer
- A Study of ARRY-520 in Patients With Relapsed or Refractory Multiple Myeloma
- A Study of Filanesib (ARRY-520) and Carfilzomib in Patients With Advanced Multiple Myeloma
- A Study of Sargramostim Plus Pembrolizumab with or Without Pemetrexed in Patients with Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy
- A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer
- A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)
- A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
- Adjuvant Antigen Specific Immunotherapy in Patients With Advanced Renal Cell Carcinoma Using Tumor Associated Peptides
- Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian Cancer
- Allogeneic ORCA-Q Stem Cell Transplant for the Treatment of Relapsed and Refractory High Risk Multiple Myeloma
- An Evaluation of the Spectra Optia CMNC Collection Procedure

### Approved for (1)

- Neoplasm

### In development for (6)

- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 3
- Autoimmune pulmonary alveolar proteinosis Phase 3
- [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 2
- [Cutaneous melanoma](https://trialight.com/data/condition/cutaneous-melanoma-c6e75b71-1c7c-59fe-a087-174eb0ec53df.md) Phase 2
- Mycobacterial infectious disease Phase 2
- [Severe acute respiratory syndrome](https://trialight.com/data/condition/severe-acute-respiratory-syndrome-7654d02a-f750-52a0-bec2-afe3b4b3c224.md) Phase 2

---

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