> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/mivalsecovatein-59cf46ee-8677-42d2-adc3-9582974a3d8d
> Record changed: 2026-10-13

# Mivalsecovatein

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

Drug type

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

## Names and chemistry

**Drug type**

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

**Drug name**

Mivalsecovatein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

### Other names (18)

- mivalsecovatein
- Mivalsecovatein
- mivalsecovatein \[INN\]
- mivalsecovatein inn
- mivalsecovateina
- Mivalsecovateina
- mivalsecovateine
- Mivalsecovateine
- nvx cov2601
- nvx cov2601 35μg
- NVX-COV2601
- NVX-CoV2601 (35μg)
- NVX-CoV2601 (5μg)
- NVX-CoV2601(35μg)
- NVX-CoV2601(50μg)
- NVX-CoV2601(5μg)
- viral spike glycoprotein nvx cov2601 665 glutamine 666 glutamine 668 glutamine 968 proline 969 proline severe acute respiratory syndrome coronavirus 2 variant xbb 1 5
- Viral spike glycoprotein NVX-CoV2601 \[665-glutamine,666-glutamine,668-glutamine,968-proline,969-proline\] (severe acute respiratory syndrome coronavirus 2 variant XBB.1.5)

## Identifiers

**CAS registry numbers**

- 2928522-52-3

**ChEMBL ID**

CHEMBL6068266

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068266)

**FDA ingredient codes (UNII)**

- 9NLL7B5W2N

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications

- **Condition**  
COVID-19

**Highest recorded phase**  
2

**Condition identifier**  
MONDO:0100096

**Subject identifier**  
D000086382

### Open Targets indications (2)

- **Condition identifier**  
MONDO\_0100096
- **Condition identifier**  
MONDO\_0100096

**Highest recorded phase**  
2

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

### Sequences (3)

- **Component**  
Sequence

**Type**  
Protein

**Sequence**  
QCVNLITRTQSYTNSETRGVYYPDKVERSSVLHSTQDLELPEESNVTWEHATHVSGINGTKREDNPALPENGVYFASTEKSNIIRGWIEGITLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLDVYQKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKEGNEKNREFVEKNIDGYFKIYSKHTPINLERDLPQGESALEPLVDLPIGINITRFQTLLALHRSYLTPVDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSETVEKGIYQTSNERVQPTESIVREPNITNLCPFHEVENATTEASVYAWNRKRISNCVADYSVINFAPFFAFKCYGVSPTKLNDLCETNVYADSFVIRGNEVSQIAPGQTGNIADYNYKLPDDETGCVIAWNSNKLDSKPSGNYNYLYRLERKSKLKPFERDISTEIYAGNKPNGVAGPNCYSPLQSYGFRPTYGVGHQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNENENGLTGTGVITESNKKELPFQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTGSNVEQTRAGCLIGAEYVNNSYECDIPIGAGTCASYQTQTSHQRAQSVASQSTTAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLKRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKYEGGENESQILPDPSKPSKRSFIEDLLENKVTLADAGFIKQYGDCLGIAARDLICAQKENGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRENGIGTQNVLYENQKLIANQENSAIGKIQDSLSSTASALGKLQDVNHNAQALNTLVKQLSSKEGAISSVLNDILSRUDEEEAEVQIDRLITGRLQSLQTYVTQQLTRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNETTAPAICHDGKAHEPREGVEVSNGTHWEVTQRNEYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVNIQKEIDRINEVAKNESLIDLQELGKYEQYIKWPWYIWLGEIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT
- **Component**  
Disulfide bridges

**Sequence**  
2-120 $ 115-149 $ 274-284 $ 319-344 $ 362-415 $ 374-508 $ 463-471 $ 521-573 $ 600-632 $ 645-654 $ 721-743 $ 726-732 $ 823-834 $ 1015-1026 $ 1065-1109
- **Component**  
Glycosylation sites (N)

**Sequence**  
45 $ 58 $ 106 $ 132 $ 148 $ 217 $ 265 $ 314 $ 326 $ 586 $ 599 $ 640 $ 692 $ 700 $ 784 $ 1057 $ 1081 $ 1117 $ 1141 $ 1156

## Related records

### Trials (4)

- Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
- [Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines](https://trialight.com/data/trial/phase-2-3-heterologous-boosting-study-with-different-dose-11366f7d-0e56-4e5c-ad7c-d51c224636f4.md)
- Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines
- Rollover Trial for Placebo Subjects Previously Enrolled Into GEN-003-002 Study

### In development for (1)

- [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 2

---

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