> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/ly-3185643-ebf45e24-5008-40d5-b3e8-40722aedfe4a
> Record changed: 2026-10-13

# LY-3185643

Highest phase reached

Phase 1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298019)

Drug type

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/32SI0A8R0O)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298019)

## Names and chemistry

**Drug type**

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/32SI0A8R0O)

**Drug name**

LY-3185643

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298019)

### Other names (7)

- ly 3185643
- Ly-3185643
- LY-3185643
- ly3185643
- Ly3185643
- LY3185643
- LY3185643 (Part B)

## Identifiers

**ChEMBL ID**

CHEMBL4298019

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298019)

**FDA ingredient codes (UNII)**

- 32SI0A8R0O

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Chemical properties

**Prodrug**

No

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (61)

- \[11C\]Carfentanil PET Study of GSK1521498
- A Clinical Trial of PRAX-944 in Participants With Essential Tremor
- A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS)
- A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis
- A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects
- A Study Assessing HMB-002 in Participants With Von Willebrand Disease
- A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED)
- A Study Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Persons
- A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma
- A Study of AZD8233 in Participants With Dyslipidemia.
- A Study of LY3143753 and LY3185643 in Healthy Participants
- A Study of LY3185643 and rGlucagon in Healthy Participants
- A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease
- A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914
- A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants
- A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants
- A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GLWL-01
- A Study to Determine the Immunogenicity and Oral Tolerance to Keyhole Limpet Hemocyanin (KLH)
- A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MKND-201 in Healthy Volunteers

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