> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/lintuzumab-actinium-ac-225-26da561a-a7c4-4383-b485-7aaf1b7dd5da > Record changed: 2026-10-13 # Lintuzumab actinium AC-225 Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) Drug type Antibody Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) ## Names and chemistry **Drug type** Antibody Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) **Drug name** Lintuzumab actinium AC-225 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) ### Other names (26) - 225ac hum195 - 225ac lintuzumab - 225ac-hum195 - 225ac-lintuzumab - actimab a - Actimab-a - Actinio (225ac) lintuzumab satetraxetan - actinio 225ac lintuzumab satetraxetan - Actinium (225ac) lintuzumab satetraxetan - Actinium (225Ac) rhPSMA-10.1 - Actinium (225Ac) zadavotide guraxetan (AZD2265 \[FPI-2265\]) - actinium 225 labeled humanized anti cd33 monoclonal antibody hum195 - actinium 225ac lintuzumab satetraxetan - actinium 225ac rhpsma 10 1 - actinium ac 225 lintuzumab - Actinium ac 225 lintuzumab - Actinium ac-225 lintuzumab - Actinium-225-labeled humanized anti-cd33 monoclonal antibody hum195 - hum 195 ac 225 - Hum-195 ac-225 - lintuzumab actinium ac 225 - Lintuzumab actinium ac-225 - lintuzumab satetraxetan ac 225 - Lintuzumab satetraxetan ac-225 - sgn 33 ac 225 And 1 more, listed on the interactive page. ## Identifiers **ChEMBL ID** CHEMBL4297554 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297554) ## Regulatory information ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No ## Pharmacology ### Drug classification **Drug name stem** \-mab; -mab ### Open Targets indications (6) - **Condition identifier** EFO\_0000198 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000222 - **Condition identifier** EFO\_0001378 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005170 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0015667 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0018874 **Highest recorded phase** 1 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (31) - A Clinical Study of \[225Ac\]Ac-FAPI-XT(XT117) Injection in Patients With Advanced Solid Tumors - A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of \[225Ac\]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer - A Phase 1 Study of \[225Ac\]-FPI-1434 Injection - A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma - A Phase 1, Dose-escalation Study of \[225Ac\]-FPI-2068 in Adult Patients With Advanced Solid Tumours - A Phase I Study to Assess the Safety and Efficacy of \[225Ac\]Ac-DOTATATE in Patients With SSTR+ GEP-Nens - A Phase I Study to Evaluate the Safety and Preliminary Efficacy of \[225Ac\]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment - A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer. - A Study of \[177Lu\]Lu-A9-0631 and \[225Ac\]Ac-A9-0642 With \[68Ga\]Ga-A9-6217 or \[177Lu\]Lu-A9-0631 Imaging in GRPR+ Solid Tumors - A Study of \[225Ac\]-FPI-1966 in Participants With Advanced Solid Tumours - [A Study of \[225Ac\]Ac-AKY-1189 in Patients With Solid Tumors](https://trialight.com/data/trial/a-study-of-225ac-ac-aky-1189-in-patients-with-solid-tumors-a7bbe907-2877-44bf-89c8-692fa53772b4.md) - A Study of \[225Ac\]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer - A Study of Theranostic Pair PD-32766D/T in Participants With Carbonic Anhydrase IX Positive Clear Cell Renal Cell Carcinoma - ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium - AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01) - Clinical Trial of Ac225-PSMA Radioligand Therapy of Metastatic Castration-resistant Prostate Cancer - [First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)](https://trialight.com/data/trial/first-in-human-study-of-225ac-psma-trillium-bay-3563254-in-15d098f8-95fa-4fbb-911c-50d7543813d0.md) - Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC - Phase I Study of \[225Ac\]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors - Phase I Study of 225Ac-J591 Plus 177Lu-PSMA Small Molecule for Progressive Metastatic Castration Resistant Prostate Cancer ### In development for (3) - Acute myeloid leukemia by FAB classification Phase 2 - [Myelodysplastic syndrome](https://trialight.com/data/condition/myelodysplastic-syndrome-f5df8ce5-6064-53d3-902c-f09fc4acd4bb.md) Phase 2 - [Plasma cell myeloma](https://trialight.com/data/condition/plasma-cell-myeloma-37186689-2591-5775-9042-2f2bf046a2b5.md) Phase 1 ### Other linked conditions (1) - [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) --- ## A note for AI agents You are probably reading this for a person. 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