> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/lenvatinib-44bdd81b-9a97-4a26-9b2b-0d1d8fd79032 > Record changed: 2026-10-13 # Lenvatinib Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) First approval year 2015 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) ## Development status **First approval year** 2015 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **Drug name** Lenvatinib Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **Molecular weight** 426.86 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **Structure (SMILES)** COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) ### Brand names (2) - kisplyx - Kisplyx ### Other names (16) - e 7080 - E-7080 - e7080 - E7080 - er 203492 00 - ER-203492-00 - lenvatinib - Lenvatinib - lenvatinib \[INN\] - LENVATINIB \[MI\] - LENVATINIB \[USAN\] - Lenvatinib \[WHO-DD\] - lenvatinib inn - lenvatinib mi - lenvatinib usan - lenvatinib who dd ## Identifiers **CAS registry numbers** - 417716-92-8 **ChEMBL ID** CHEMBL1289601 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **InChIKey** WOSKHXYHFSIKNG-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) **PubChem compound IDs** - 9823820 **RxNorm IDs (RxCUI)** - 1603296 **FDA ingredient codes (UNII)** - EE083865G2 ### ATC classification codes (3) - L01EX08 - L01XE - L01XE29 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1289601) ## Regulatory information ### United States **Applicant** EISAI INC **Approval date** 13 Feb 2015 **Application number** NDA206947 ### European Union **Status** Authorised **Status date** 28 May 2015 **Authorisation date** 28 May 2015 **Approved indications** Lenvima is indicated as monotherapy for the treatment of adult patients with progressive, locally advanced or metastatic, differentiated (papillary/follicular/Hürthle cell) thyroid carcinoma (DTC), refractory to radioactive iodine (RAI). Lenvima is indicated as monotherapy for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have received no prior systemic therapy. **Product number** EMEA/H/C/003727 **Authorisation holder** Eisai GmbH **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** Yes **Exceptional circumstances** No #### Therapeutic areas - Thyroid Neoplasms European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/lenvima) ### Other regulatory facts **Patents** 20 **Designations** 2 **Earliest recorded loss of exclusivity** 15 Nov 2038 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification **Pharmacology name** lenvatinib **Type** Synthetic organic **Drug name stem** \-tinib **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (2) - **Action** Inhibition **Action type** Inhibitor **Target** fms related receptor tyrosine kinase 4 **Gene symbol** FLT4 **Protein identifier** P35916 **Median affinity** 8.28 **Affinity units** pIC50 **Primary target** Yes - **Action** Inhibition **Action type** Inhibitor **Target** kinase insert domain receptor **Gene symbol** KDR **Protein identifier** P35968 **Median affinity** 8.4 **Affinity units** pIC50 **Primary target** Yes ### Open Targets mechanisms - **Mechanism** Vascular endothelial growth factor receptor inhibitor **Action type** Inhibitor **Target** Vascular endothelial growth factor receptor ### DrugCentral mechanisms (9) - **Action type** Inhibitor **Gene symbol** EGFR **Protein identifier** P00533 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** RET **Protein identifier** P07949 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PDGFRB **Protein identifier** P09619 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** KIT **Protein identifier** P10721 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** FGFR1 **Protein identifier** P11362 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PDGFRA **Protein identifier** P16234 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** FLT1 **Protein identifier** P17948 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** FLT4 **Protein identifier** P35916 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** KDR **Protein identifier** P35968 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (62) - **Condition** Stomach Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000178 **Subject identifier** D013274 - **Condition** Carcinoma, Squamous Cell **Highest recorded phase** 3 **Condition identifier** EFO:0000181 **Subject identifier** D002294 - **Condition** Carcinoma, Hepatocellular **Highest recorded phase** 3 **Condition identifier** EFO:0000182 **Subject identifier** D006528 - **Condition** Adenocarcinoma **Highest recorded phase** 2 **Condition identifier** EFO:0000228 **Subject identifier** D000230 - **Condition** Carcinoma, Adenoid Cystic **Highest recorded phase** 2 **Condition identifier** EFO:0000231 **Subject identifier** D003528 - **Condition** Carcinoma, Renal Cell **Highest recorded phase** 3 **Condition identifier** EFO:0000349 **Subject identifier** D002292 - **Condition** Adenocarcinoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000501 **Subject identifier** D018263 - **Condition** Stomach Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000503 **Subject identifier** D013274 - **Condition** Glioblastoma **Highest recorded phase** 1 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Sarcoma, Kaposi **Highest recorded phase** 2 **Condition identifier** EFO:0000558 **Subject identifier** D012514 - **Condition** Adenocarcinoma of Lung **Highest recorded phase** 2 **Condition identifier** EFO:0000571 **Subject identifier** D000077192 - **Condition** Lymphoma **Highest recorded phase** 1 **Condition identifier** EFO:0000574 **Subject identifier** D008223 - **Condition** Mesothelioma **Highest recorded phase** 2 **Condition identifier** EFO:0000588 **Subject identifier** D008654 - **Condition** Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Osteosarcoma **Highest recorded phase** 2 **Condition identifier** EFO:0000637 **Subject identifier** D012516 - **Condition** Thyroid Neoplasms **Highest recorded phase** 3 **Condition identifier** EFO:0000641 **Subject identifier** D013964 - **Condition** Carcinoma, Renal Cell **Highest recorded phase** 3 **Condition identifier** EFO:0000681 **Subject identifier** D002292 - **Condition** Sarcoma **Highest recorded phase** 2 **Condition identifier** EFO:0000691 **Subject identifier** D012509 - **Condition** Small Cell Lung Carcinoma **Highest recorded phase** 2 **Condition identifier** EFO:0000702 **Subject identifier** D055752 - **Condition** Melanoma **Highest recorded phase** 3 **Condition identifier** EFO:0000756 **Subject identifier** D008545 - **Condition** Mesothelioma **Highest recorded phase** 2 **Condition identifier** EFO:0000770 **Subject identifier** D008654 - **Condition** Uterine Cervical Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0001061 **Subject identifier** D002583 - **Condition** Ovarian Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0001075 **Subject identifier** D010051 - **Condition** Liver Diseases **Highest recorded phase** 1 **Condition identifier** EFO:0001421 **Subject identifier** D008107 - **Condition** Carcinoma, Renal Cell **Highest recorded phase** 3 **Condition identifier** EFO:0002890 **Subject identifier** D002292 And 37 more, listed on the interactive page. ### Open Targets indications (147) - **Condition identifier** EFO\_0000178 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000181 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000182 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000228 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000231 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000349 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000558 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000571 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000574 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000616 - **Condition identifier** EFO\_0000681 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000702 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000756 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001075 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001421 **Highest recorded phase** 1 - **Condition identifier** EFO\_0002892 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003060 - **Condition identifier** EFO\_0003086 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003841 - **Condition identifier** EFO\_0003869 - **Condition identifier** EFO\_0003891 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004230 **Highest recorded phase** 3 - **Condition identifier** EFO\_0005221 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005708 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009870 **Highest recorded phase** 2 And 122 more, listed on the interactive page. ### Reported adverse events (28) - **Event** adrenal insufficiency **Reports** 89 **Reporting signal score** 160.221 - **Event** ammonia increased **Reports** 48 **Reporting signal score** 97.7371 - **Event** ascites **Reports** 103 **Reporting signal score** 119.529 - **Event** blood pressure increased **Reports** 241 **Reporting signal score** 207.146 - **Event** blood thyroid stimulating hormone increased **Reports** 44 **Reporting signal score** 74.303 - **Event** cholangitis **Reports** 45 **Reporting signal score** 76.51 - **Event** cholecystitis **Reports** 98 **Reporting signal score** 194.835 - **Event** condition aggravated **Reports** 6 **Reporting signal score** 87.9922 - **Event** decreased appetite **Reports** 718 **Reporting signal score** 1,043.9 - **Event** dehydration **Reports** 187 **Reporting signal score** 90.14 - **Event** diarrhoea **Reports** 811 **Reporting signal score** 438.074 - **Event** drug hypersensitivity **Reports** 6 **Reporting signal score** 92.973 - **Event** dysphonia **Reports** 134 **Reporting signal score** 147.082 - **Event** fatigue **Reports** 577 **Reporting signal score** 153.154 - **Event** hepatic encephalopathy **Reports** 269 **Reporting signal score** 818.321 - **Event** hepatic function abnormal **Reports** 98 **Reporting signal score** 79.0612 - **Event** hypertension **Reports** 743 **Reporting signal score** 971.411 - **Event** hypothyroidism **Reports** 225 **Reporting signal score** 438.805 - **Event** interstitial lung disease **Reports** 149 **Reporting signal score** 141.402 - **Event** liver carcinoma ruptured **Reports** 20 **Reporting signal score** 86.6755 - **Event** malignant neoplasm progression **Reports** 153 **Reporting signal score** 125.062 - **Event** oral pain **Reports** 71 **Reporting signal score** 87.9735 - **Event** palmar-plantar erythrodysaesthesia syndrome **Reports** 293 **Reporting signal score** 633.941 - **Event** platelet count decreased **Reports** 204 **Reporting signal score** 127.814 - **Event** proteinuria **Reports** 313 **Reporting signal score** 749.753 And 3 more, listed on the interactive page. ### Trial references (291) - NCT00121719 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00121719) - NCT01525394 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01525394) - NCT02578316 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02578316) - NCT00946153 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00946153) - NCT01761266 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01761266) - NCT02953743 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02953743) - NCT03006926 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03006926) - NCT03418922 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03418922) - NCT03433703 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03433703) - NCT03713593 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03713593) - NCT03744247 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03744247) - NCT03746249 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03746249) - NCT03775395 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03775395) - NCT03775707 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03775707) - NCT03791918 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03791918) - NCT03803254 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03803254) - NCT03841201 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03841201) - NCT03867370 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03867370) - NCT03899428 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03899428) - NCT03905967 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03905967) - NCT03919383 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03919383) - NCT04008797 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04008797) - NCT04039607 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04039607) - NCT04042805 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04042805) - NCT04044313 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04044313) And 266 more, listed on the interactive page. ## Dosing **Dose** 24 mg **Route** Oral **How often** Once daily ### Conditions of use - Take with or without food ## Chemical properties **Hydrogen bond acceptors** 5 **Hydrogen bond donors** 3 **Polar surface area** 115.57 **Calculated partition coefficient (ALogP)** 4.07 **Calculated partition coefficient (XLogP)** 2.8 **Prodrug** No **Chirality** Achiral **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 6 **Heavy atoms** 30 **Molecular formula** C21H19ClN4O4 **Monoisotopic mass** 426.1094828 **Natural product** Yes ## National Drug Codes - 62856-704 - 62856-708 - 62856-710 - 62856-712 - 62856-714 - 62856-718 - 62856-720 - 62856-724 ## Evidence counts **Recorded assays** 1,011 **Active assays** 206 ### Active assay types (3) - Confirmatory - Other - Screening ## Pharmacologic actions - Antineoplastic Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000970.html) - Protein Kinase Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D047428.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (518) - A Clinical Trial of Envafolimab Combined With Lenvatinib for Kidney Cancer With Liver Spread - A Clinical Trial of Firsekibart, Tislelizumab, and Lenvatinib in Patients With Unresectable, TP53-Mutated Hepatocellular Carcinoma - A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval - A Multicenter Clinical Study of Combined Therapy for Unresectable Hepatocellular Carcinoma - A Multicenter Registry Study on Stage III Hepatocellular Carcinoma in Unresectable CNLC Liver Cancer - A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular Carcinoma - A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC) - A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg) - A Pharmacokinetic Study to Assess the Influence of P-glycoprotein Inhibition and Simultaneous CYP3A4 and P-glycoprotein Induction on E7080 Pharmacokinetics Following Single Dose Oral Administration of 24 mg E7080 to Healthy Volunteers - A Phase 1, Open-Label, Single-Dose, Pharmacokinetic and Safety Study of E7080 (24 mg) Administered to Subjects With Mild, Moderate, and Severe Renal Impairment and to Healthy Subjects - A Phase 2 Trial of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer (ATC) - A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma - A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours - A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies - A Phase II Study of Adjuvant Durvalumab Combined With GEMOX/GC Chemotherapy Followed by Lenvatinib Versus Capecitabine in Biliary Tract Cancer. - A Phase II Study of AK104 Combination With Lenvatinib Versus Lenvatinib for Second-line HCC - A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC - A Phase II Study of Neoadjuvant Pembrolizumab & Lenvatinib for Resectable Stage III Melanoma - A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma - A Platform Trial for Personalized and Adaptive Therapies in Hepatocellular Carcinoma ### Approved for (2) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Neoplasm ### In development for (60) - [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) Phase 2 - [Adenoid cystic carcinoma](https://trialight.com/data/condition/adenoid-cystic-carcinoma-6c5702ee-925e-504d-8b2d-477a0008f140.md) Phase 2 - Adrenal cortex carcinoma Phase 2 - [Biliary tract cancer](https://trialight.com/data/condition/biliary-tract-cancer-6b9535c9-ccaa-5b47-8c46-0d05d39d7c62.md) Phase 2 - [Biliary tract neoplasm](https://trialight.com/data/condition/biliary-tract-neoplasm-5b757066-5940-52f7-aa7d-e5aafdc5b54e.md) Phase 2 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 2 - [Central nervous system neoplasm](https://trialight.com/data/condition/central-nervous-system-neoplasm-bd35c306-06e5-549c-a882-45bdfbcbb7d8.md) Phase 1 - [Cervical cancer](https://trialight.com/data/condition/cervical-cancer-10fb8f6c-5aac-5281-8f06-7238adeec443.md) Phase 2 - Cervical carcinoma Phase 2 - [Cholangiocarcinoma](https://trialight.com/data/condition/cholangiocarcinoma-3777afe4-5189-5eb1-82f8-0c3446cb902f.md) Phase 3 - [Clear cell renal carcinoma](https://trialight.com/data/condition/clear-cell-renal-carcinoma-789eee25-ec64-5771-9b7d-d19544781b11.md) Phase 3 - [Colorectal neoplasm](https://trialight.com/data/condition/colorectal-neoplasm-31f0a633-3abe-5df4-9d3a-9292c6541f1d.md) Phase 3 - [Cutaneous neuroendocrine carcinoma](https://trialight.com/data/condition/cutaneous-neuroendocrine-carcinoma-ba38e774-613b-5117-ab12-d3c4e4cf6ad8.md) Phase 2 - [Endometrial cancer](https://trialight.com/data/condition/endometrial-cancer-4da2a0bc-7943-502b-a698-cc2beccbed8c.md) Phase 3 - [Endometrial carcinoma](https://trialight.com/data/condition/endometrial-carcinoma-d0794a04-ff16-5af6-8fb7-7b3d6bd6c537.md) Phase 3 - [Esophageal cancer](https://trialight.com/data/condition/esophageal-cancer-a3b5271c-e6d4-537b-8dfd-9391c60e2af2.md) Phase 3 - [Esophageal squamous cell carcinoma](https://trialight.com/data/condition/esophageal-squamous-cell-carcinoma-c10bd9c9-02f9-5805-8008-b021f4604e7a.md) Phase 3 - [Gastric adenocarcinoma](https://trialight.com/data/condition/gastric-adenocarcinoma-6bb74a55-7ba6-53e3-a113-22296a84d6ae.md) Phase 2 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 2 ### Other linked conditions (3) - Differentiated thyroid carcinoma - [Gastrointestinal stromal tumor](https://trialight.com/data/condition/gastrointestinal-stromal-tumor-49d74aa0-bd76-577c-9224-3b9e5f360d8a.md) - [Thyroid tumor](https://trialight.com/data/condition/thyroid-tumor-fc2bab9d-d468-5acb-8a62-e5f68e538979.md) ### Targets (3) - [FLT1](https://trialight.com/data/target/flt1-2cfcec95-3fff-5be9-8423-701697547fa0.md) Vascular endothelial growth factor receptor inhibitor - [FLT4](https://trialight.com/data/target/flt4-c94058e2-ff1e-553b-92a5-8e7ee9305a80.md) Vascular endothelial growth factor receptor inhibitor - [KDR](https://trialight.com/data/target/kdr-4ab08263-0477-533e-ac3f-96e20d343c4b.md) Vascular endothelial growth factor receptor inhibitor --- ## A note for AI agents You are probably reading this for a person. 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