> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/ledismase-176da9be-9dac-40ac-b550-0c9ffa897386
> Record changed: 2026-10-13

# Ledismase

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

Drug type

Enzyme

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

## Names and chemistry

**Drug type**

Enzyme

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

**Drug name**

Ledismase

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

### Other names (30)

- dismutase superoxide human copper zinc subunit cyclic 57 146 disulfide dim
- DISMUTASE, SUPEROXIDE (HUMAN COPPER-ZINC SUBUNIT), CYCLIC (57->146)-DISULFIDE, DIM
- edismase
- Edismase
- EDISMASE (GENETICAL RECOMBINATION)
- EDISMASE \[JAN\]
- edismase genetical recombination
- edismase jan
- human sod 1
- Human sod-1
- ledismasa
- Ledismasa
- ledismase
- Ledismase
- ledismase \[INN\]
- ledismase inn
- oxsodrol
- Oxsodrol
- recombinant superoxide dismutase human
- RECOMBINANT SUPEROXIDE DISMUTASE, HUMAN
- SUPEROXIDE DISMUTASE (CU-ZN) HUMAN
- Superoxide dismutase (human)
- superoxide dismutase cu zn human
- superoxide dismutase human
- SUPEROXIDE DISMUTASE HUMAN (E. COLI)

And 5 more, listed on the interactive page.

## Identifiers

**CAS registry numbers**

- 149394-67-2

**ChEMBL ID**

CHEMBL2109126

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109126)

**PubChem compound IDs**

- 72941695

**RxNorm IDs (RxCUI)**

- 1742510

**FDA ingredient codes (UNII)**

- 0786H5RV0T

## Regulatory information

### Other regulatory facts

**Patents**

0

**Designations**

1

**First in class**

No

**Fast track**

No

**Breakthrough designation**

No

**Orphan designation**

No

**Priority review**

No

**Orphan exclusivity**

No

**Accelerated approval**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-ase

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (39)

- A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
- A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
- [A Study to Learn About a Vaccine Against E Coli in Healthy Adults](https://trialight.com/data/trial/a-study-to-learn-about-a-vaccine-against-e-coli-in-healthy-89601220-8dfb-4fd1-9def-253f7cee3da4.md)
- Additive Effect of Probiotics (Mutaflor®) in Patients With Ulcerative Colitis on 5-ASA Treatment.
- Anti-inflammatory Effects of GTS-21 After LPS
- Assessing NOS Uptake With PET Imaging in Lung Inflammation
- Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli
- Clinical Experiment of Helicobacter Pylori Transmission
- E. Coli 83972 Induced Asymptomatic Bacteriuria (ABU) in Patients With Recurrent Urinary Tract Infections (UTI)
- E. Coli Nissle in Oncology
- Effects of BCG on Immune Response
- Enteroaggregative E.Coli (EAEC)
- Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients
- Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas
- Inactivated Poliovirus Vaccine (IPV) With or Without E.Coli Double Mutant Heat-Labile Toxin (dmLT) Challenge Study in Healthy Adults
- Individual Differences in Acute Response to Experimental Inflammation: Microcirculatory Changes and Psychological Predictors
- Inflammatory Challenge in Human Aggression.
- Investigation of the Effect of E.-Coli-Nissle as Supporting Therapy to Standard Care of Diabetes Mellitus Type II
- Low-dose Challenge Model With Enterotoxigenic E Coli
- Low-Dose Endotoxemia and the Acute Phase Response

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