> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/kn-026-d075c579-0639-493d-a4a1-0f2c248a69e9 > Record changed: 2026-10-13 # KN-026 Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594568) Drug type Unknown ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594568) ## Names and chemistry **Drug type** Unknown **Drug name** KN-026 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594568) ### Other names (11) - anbenitamab - Anbenitamab - anti her2 bsab kn026 - Anti-her2 bsab kn026 - kn 026 - Kn 026 - Kn-026 - KN-026 - kn026 - Kn026 - KN026 ## Identifiers **ChEMBL ID** CHEMBL4594568 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594568) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Mechanisms of action - **Mechanism** Receptor protein-tyrosine kinase erbB-2 inhibitor **Action type** Inhibitor **Target** Receptor tyrosine-protein kinase erbB-2 **Protein identifier** P04626 ### Open Targets mechanisms - **Mechanism** Receptor protein-tyrosine kinase erbB-2 inhibitor **Action type** Inhibitor **Target** Receptor tyrosine-protein kinase erbB-2 ### Investigated indications (4) - **Condition** Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Stomach Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0001056 **Subject identifier** D013274 - **Condition** Adenocarcinoma **Highest recorded phase** 2 **Condition identifier** MONDO:0003219 **Subject identifier** D000230 - **Condition** Breast Neoplasms **Highest recorded phase** 3 **Condition identifier** MONDO:0007254 **Subject identifier** D001943 ### Open Targets indications (7) - **Condition identifier** EFO\_0000616 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0001056 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0003060 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0003219 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005575 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0007254 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0007254 **Highest recorded phase** 3 ### Trial references (6) - NCT03925974 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03925974) - NCT04165993 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04165993) - NCT04881929 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04881929) - NCT05838066 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05838066) - NCT04521179 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04521179) - NCT05427383 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05427383) ## Chemical properties **Prodrug** No **Inorganic** No **Natural product** No ## Related records ### Trials (16) - A Clinical Study of SYS6023 Combination Therapy for Advanced Breast Cancer - A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer - [A Phase III Study of KN026 in Combination With HB1801 as Adjuvant Therapy for Resectable HER2-Positive Breast Cancer](https://trialight.com/data/trial/a-phase-iii-study-of-kn026-in-combination-with-hb1801-as-325b2e5c-9de2-49a1-a980-2dbe6872428b.md) - A Study of KN026-based Combination Therapy in HER2-positive Gastric Cancer - JSKN003 Combined Treatment of HER2-positive Gastric Cancer - KN026 Combined With KN046 in Subjects With HER2 Positive Solid Tumor - KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy - KN026 in Patients With HER2 Expressing Breast Cancer and Gastric Cancer - KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer - KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma - Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC - Study of KN026 Combined With KN046 in Patients With Locally Advanced HER2-positive Solid Tumors - Study of KN026 in Combination With Docetaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer - Study of KN026 in Combination With Palbociclib and Fulvestrant in Patients With Advanced Breast Cancer - Study of KN026 Monotherapy or Combination Therapy in Patients With Metastatic Breast Cancer - Trial of KN026 in Patients With HER2-positive Advanced Malignant Breast Cancer and Gastric Cancer ### In development for (4) - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 3 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 2 - [Gastroesophageal junction adenocarcinoma](https://trialight.com/data/condition/gastroesophageal-junction-adenocarcinoma-de7e280e-cbd1-5266-a5dd-dda00261a706.md) Phase 2 - Neoplasm Phase 2 ### Targets (1) - [ERBB2](https://trialight.com/data/target/erbb2-900ec94b-8cc2-5864-a53d-4b5ed23c71f5.md) Receptor protein-tyrosine kinase erbB-2 inhibitor --- ## A note for AI agents You are probably reading this for a person. 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