> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/ketoconazole-4cbf7ed7-27d9-4804-8c85-c9089ae940d6 > Record changed: 2026-11-04 # Ketoconazole Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) First approval year 1981 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) ## Development status **First approval year** 1981 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **Drug name** Ketoconazole Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **Molecular weight** 531.44 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **Structure (SMILES)** CC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) ### Brand names (28) - daktarin gold - Daktarin gold - daktarin intensiv - Daktarin intensiv - dandrazol - Dandrazol - dandrid - Dandrid - extina - Extina - ketoconazole - Ketoconazole - ketoconazole hra - Ketoconazole hra - ketopine - Ketopine - ketozole - Ketozole - nizoral - Nizoral - nizoral a d - Nizoral a-d - nizoral anti dandruff - Nizoral anti-dandruff - nizorelle And 3 more, listed on the interactive page. ### Other names (52) - (±)-CIS-1-ACETYL-4-(P-((2-(2,4-DICHLOROPHENYL)-2-(IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE - cis 1 acetyl 4 p 2 2 4 dichlorophenyl 2 imidazol 1 ylmethyl 1 3 dioxolan 4 yl methoxy phenyl piperazine - j02ab02 - J02AB02 - ketoconazol - Ketoconazol - ketoconazole - Ketoconazole - KETOCONAZOLE \[EP IMPURITY\] - KETOCONAZOLE \[EP MONOGRAPH\] - KETOCONAZOLE \[HSDB\] - ketoconazole \[INN\] - KETOCONAZOLE \[JAN\] - KETOCONAZOLE \[MART.\] - KETOCONAZOLE \[MI\] - KETOCONAZOLE \[ORANGE BOOK\] - KETOCONAZOLE \[USAN\] - KETOCONAZOLE \[USP IMPURITY\] - KETOCONAZOLE \[USP MONOGRAPH\] - KETOCONAZOLE \[USP-RS\] - KETOCONAZOLE \[VANDF\] - Ketoconazole \[WHO-DD\] - ketoconazole ep impurity - ketoconazole ep monograph - ketoconazole hsdb And 27 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 65277-42-1 **ChEMBL ID** CHEMBL157101 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **InChIKey** XMAYWYJOQHXEEK-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) **PubChem compound IDs** - 3823 **RxNorm IDs (RxCUI)** - 6135 **FDA ingredient codes (UNII)** - R9400W927I ### ATC classification codes (5) - D01AC08 - G01AF11 - H02CA03 - J02AB02 - V03 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL157101) ## Regulatory information ### United States **Applicant** KRAMER **Approval date** 10 Oct 1997 **Application number** NDA020310 ### European Union **Status** Authorised **Status date** 18 Nov 2014 **Authorisation date** 18 Nov 2014 **Approved indications** Ketoconazole Esteve is indicated for the treatment of endogenous Cushing’s syndrome in adults and adolescents above the age of 12 years. **Product number** EMEA/H/C/003906 **Authorisation holder** Esteve Pharmaceuticals, S.A. **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** Yes **Accelerated assessment** Yes **Exceptional circumstances** No #### Therapeutic areas - Cushing Syndrome European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/ketoconazole-esteve) ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Over the counter **Boxed warning** Yes ## Approval status **United States (FDA)** Approved **European Union (EMA)** Authorised ## Pharmacology ### Drug classification **Pharmacology name** ketoconazole **Type** Synthetic organic **Drug name stem** \-conazole **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral - topical ### Mechanisms of action (3) - **Action** Channel blocker **Action type** Channel blocker **Target** Kv1.8 **Gene symbol** KCNA10 **Protein identifier** Q16322 **Median affinity** 6.3 **Affinity units** pIC50 - **Action** Inhibition **Action type** Inhibitor **Target** CYP3A4 **Gene symbol** CYP3A4 **Protein identifier** P08684 **Median affinity** 7 **Affinity units** pKi - **Mechanism** Cytochrome P450 51 inhibitor **Action type** Inhibitor **Target** Lanosterol 14-alpha demethylase **Protein identifier** P10613 ### Open Targets mechanisms - **Mechanism** Cytochrome P450 51 inhibitor **Action type** Inhibitor **Target** Lanosterol 14-alpha demethylase ### DrugCentral mechanisms (5) - **Action type** Blocker **Gene symbol** KCNA10 **Protein identifier** Q16322 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** CYP17A1 **Protein identifier** P05093 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** ERG11 **Protein identifier** P10613 **Organism** Candida albicans (strain SC5314 / ATCC MYA-2876) - **Action type** Inhibitor **Gene symbol** CYP11B1 **Protein identifier** P15538 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** CYP11B2 **Protein identifier** P19099 **Organism** Homo sapiens **Target development level** Chemical evidence ### Investigated indications (44) - **Condition** Leukemia, Lymphocytic, Chronic, B-Cell **Highest recorded phase** 1 **Condition identifier** EFO:0000095 **Subject identifier** D015451 - **Condition** Leukemia, Myelogenous, Chronic, BCR-ABL Positive **Highest recorded phase** 2 **Condition identifier** EFO:0000339 **Subject identifier** D015464 - **Condition** Pulmonary Disease, Chronic Obstructive **Highest recorded phase** 1 **Condition identifier** EFO:0000341 **Subject identifier** D029424 - **Condition** Glioblastoma **Highest recorded phase** 0.5 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Immune System Diseases **Highest recorded phase** 1 **Condition identifier** EFO:0000540 **Subject identifier** D007154 - **Condition** Lymphoma **Highest recorded phase** 1 **Condition identifier** EFO:0000574 **Subject identifier** D008223 - **Condition** Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Neuroblastoma **Highest recorded phase** 1 **Condition identifier** EFO:0000621 **Subject identifier** D009447 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Melanoma **Highest recorded phase** 1 **Condition identifier** EFO:0000756 **Subject identifier** D008545 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0001663 **Subject identifier** D011471 - **Condition** Insulin Resistance **Highest recorded phase** 0.5 **Condition identifier** EFO:0002614 **Subject identifier** D007333 - **Condition** Hepatitis C **Highest recorded phase** 1 **Condition identifier** EFO:0003047 **Subject identifier** D006526 - **Condition** Cushing Syndrome **Highest recorded phase** 4 **Condition identifier** EFO:0003099 **Subject identifier** D003480 - **Condition** Osteoporosis **Highest recorded phase** 1 **Condition identifier** EFO:0003882 **Subject identifier** D010024 - **Condition** Acne Vulgaris **Highest recorded phase** 3 **Condition identifier** EFO:0003894 **Subject identifier** D000152 - **Condition** Premature Birth **Highest recorded phase** 1 **Condition identifier** EFO:0003917 **Subject identifier** D047928 - **Condition** Vaginosis, Bacterial **Highest recorded phase** 3 **Condition identifier** EFO:0003932 **Subject identifier** D016585 - **Condition** Erectile Dysfunction **Highest recorded phase** 1 **Condition identifier** EFO:0004234 **Subject identifier** D007172 - **Condition** Adrenal Gland Diseases **Highest recorded phase** 4 **Condition identifier** EFO:0005539 **Subject identifier** D000307 - **Condition** Lymphoma, Non-Hodgkin **Highest recorded phase** 1 **Condition identifier** EFO:0005952 **Subject identifier** D008228 - **Condition** Nausea **Highest recorded phase** 1 **Condition identifier** EFO:0006911 **Subject identifier** D009325 - **Condition** Blastomycosis **Highest recorded phase** 4 **Condition identifier** EFO:0007174 **Subject identifier** D001759 - **Condition** Tinea Versicolor **Highest recorded phase** 1 **Condition identifier** EFO:0007439 **Subject identifier** D014010 - **Condition** Tinea **Highest recorded phase** 4 **Condition identifier** EFO:0007510 **Subject identifier** D014005 And 19 more, listed on the interactive page. ### Open Targets indications (70) - **Condition identifier** EFO\_0000339 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000341 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000519 - **Condition identifier** EFO\_0000540 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000756 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003099 - **Condition identifier** EFO\_0003894 **Highest recorded phase** 3 - **Condition identifier** EFO\_0004234 **Highest recorded phase** 1 - **Condition identifier** EFO\_0005539 - **Condition identifier** EFO\_0006461 **Highest recorded phase** 2 - **Condition identifier** EFO\_0007174 - **Condition identifier** EFO\_0007439 **Highest recorded phase** 1 - **Condition identifier** EFO\_0007510 - **Condition identifier** EFO\_0007512 - **Condition identifier** EFO\_0007543 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009363 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009784 **Highest recorded phase** 2 - **Condition identifier** EFO\_1000764 - **Condition identifier** EFO\_1001494 **Highest recorded phase** 2 - **Condition identifier** GO\_0042060 **Highest recorded phase** 2 - **Condition identifier** HP\_0000027 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0001134 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0001628 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0002026 **Highest recorded phase** 3 And 45 more, listed on the interactive page. ### Warnings (3) - **Warning** Black Box Warning **Effect** cardiotoxicity - **Warning** Black Box Warning **Effect** hepatotoxicity - **Warning** Withdrawn **Effect** hepatotoxicity **Description** Liver toxicity is more frequent and severe than with other antifungal treatments; Elevated risk of early onset liver damage **Year** 2011 ### Open Targets warnings (4) - **Warning** Black Box Warning **Effect** cardiotoxicity **Country** United States - **Warning** Black Box Warning **Effect** hepatotoxicity **Country** United States - **Warning** Withdrawn **Effect** hepatotoxicity **Description** Liver toxicity is more frequent and severe than with other antifungal treatments; Elevated risk of early onset liver damage **Year** 2011 **Country** Guatemala; Madagascar **Condition** drug-induced liver injury - **Warning** Withdrawn **Effect** hepatotoxicity **Description** Liver toxicity is more frequent and severe than with other antifungal treatments; Elevated risk of early onset liver damage **Year** 2011 **Country** Guatemala; Madagascar **Condition** hepatotoxicity ### Reported adverse events (35) - **Event** abortion spontaneous **Reports** 33 **Reporting signal score** 43.1054 - **Event** adrenal insufficiency **Reports** 25 **Reporting signal score** 58.573 - **Event** alanine aminotransferase increased **Reports** 35 **Reporting signal score** 31.4507 - **Event** alcohol intolerance **Reports** 7 **Reporting signal score** 28.2187 - **Event** aspartate aminotransferase increased **Reports** 34 **Reporting signal score** 33.053 - **Event** bladder dilatation **Reports** 5 **Reporting signal score** 15.409 - **Event** blood alkaline phosphatase increased **Reports** 16 **Reporting signal score** 16.2414 - **Event** blood chloride decreased **Reports** 8 **Reporting signal score** 19.1983 - **Event** cholestasis **Reports** 14 **Reporting signal score** 15.1155 - **Event** colour vision tests normal **Reports** 3 **Reporting signal score** 21.4526 - **Event** contraindication to medical treatment **Reports** 11 **Reporting signal score** 40.9882 - **Event** cortisol increased **Reports** 9 **Reporting signal score** 46.0676 - **Event** deafness bilateral **Reports** 8 **Reporting signal score** 23.8348 - **Event** drug interaction **Reports** 137 **Reporting signal score** 189.729 - **Event** hepatic necrosis **Reports** 8 **Reporting signal score** 18.8563 - **Event** hepatitis **Reports** 20 **Reporting signal score** 24.8742 - **Event** hepatitis cholestatic **Reports** 9 **Reporting signal score** 15.7669 - **Event** hepatotoxicity **Reports** 28 **Reporting signal score** 50.5472 - **Event** hypokalaemia **Reports** 27 **Reporting signal score** 28.0871 - **Event** jaundice **Reports** 22 **Reporting signal score** 27.2227 - **Event** mixed liver injury **Reports** 11 **Reporting signal score** 31.7883 - **Event** multiple chemical sensitivity **Reports** 4 **Reporting signal score** 21.444 - **Event** pneumonia mycoplasmal **Reports** 8 **Reporting signal score** 29.8381 - **Event** premature rupture of membranes **Reports** 9 **Reporting signal score** 23.257 - **Event** prostate cancer metastatic **Reports** 6 **Reporting signal score** 16.5065 And 10 more, listed on the interactive page. ### Trial references (85) - NCT00000579 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000579) - NCT00002760 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002760) - NCT00002855 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002855) - NCT00003084 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00003084) - NCT00006371 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00006371) - NCT00024167 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00024167) - NCT00027859 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00027859) - NCT00030654 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00030654) - NCT00309894 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00309894) - NCT00460031 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00460031) - NCT00673127 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00673127) - NCT00859781 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00859781) - NCT00895310 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00895310) - NCT00953576 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00953576) - NCT01036594 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01036594) - NCT02494713 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02494713) - NCT03261336 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03261336) - NCT00003249 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00003249) - NCT00096317 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00096317) - NCT00162214 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00162214) - NCT00238225 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00238225) - NCT00697437 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00697437) - NCT01114191 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01114191) - NCT01218620 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01218620) - NCT01267084 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01267084) And 60 more, listed on the interactive page. ## Dosing **How often** 1 to 3 times daily ### Conditions of use (4) - Avoid use on open wounds, cuts, or raw skin - Do not reuse - Thoroughly wipe the affected area - Use a pad for each wipe ## Chemical properties **Hydrogen bond acceptors** 7 **Hydrogen bond donors** 0 **Polar surface area** 69.06 **Calculated partition coefficient (ALogP)** 4.21 **Calculated partition coefficient (XLogP)** 4.3 **Prodrug** No **Chirality** Racemic **Inorganic** No **Rule-of-five violations** 1 **Rotatable bonds** 7 **Heavy atoms** 36 **Molecular formula** C26H28Cl2N4O4 **Monoisotopic mass** 530.1487608 **Natural product** Yes ## National Drug Codes - 0093-3219 - 0168-0099 - 0713-0592 - 16714-955 - 21922-025 - 35573-433 - 43538-530 - 45802-465 - 45802-532 - 51407-279 - 60429-020 - 63187-774 - 63646-010 - 64380-827 - 69292-224 - 70700-160 - 70954-662 - 71205-105 - 71713-097 - 72189-180 - 72189-422 - 72189-428 - 72578-156 - 72603-878 - 72789-052 And 33 more, listed on the interactive page. ## Evidence counts **Recorded assays** 6,484 **Active assays** 620 ### Active assay types (2) - Confirmatory - Other ## Biological measurements These details could not be displayed. ## Related records ### Trials (170) - 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer - A 4 Week Study of Elidel (Pimecrolimus) for the Treatment of Seborrheic Dermatitis - A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - A Drug Interaction Study of JNJ-31001074 and Ketoconazole in Healthy Volunteers - A Drug Interaction Study With Fluticasone Furoate/GW642444 Inhalation Powder and Ketoconazole - A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers - A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors - A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma - A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects - A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers - A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer - A Pilot Study of the Treatment of Central Serous Chorioretinopathy With Ketoconazole - A Randomized, Multiple Dose, Double Blind, 5-way Crossover Study of the Electrocardiographic (ECG) Effects of Bilastine - [A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor.](https://trialight.com/data/trial/a-study-comparing-ketoconazole-shampoo-2-and-ketoconazole-2-708721ea-a471-4fd6-b550-3faa4d4dbe1f.md) - A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ABT-333 - A Study of Baricitinib When Administered With Ketoconazole or Fluconazole in Healthy Participants - A Study of LY2484595 on Pharmacokinetics in Healthy Participants - A Study of RO5190591 (Danoprevir) in Healthy Volunteers - A Study of the Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy Volunteers - A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers ### Approved for (7) - Adrenal gland disorder - Blastomycosis - [Cushing syndrome](https://trialight.com/data/condition/cushing-syndrome-bf694ab1-28dd-5b0a-bb0e-fbe035b96fed.md) - Fungal infectious disease - Seborrheic dermatitis - Tinea infection - Tinea pedis ### In development for (49) - [Acne](https://trialight.com/data/condition/acne-02478aa3-966b-5ffb-a257-6dbe85c14e58.md) Phase 3 - Acute respiratory distress syndrome Phase 3 - [Adult acute respiratory distress syndrome](https://trialight.com/data/condition/adult-acute-respiratory-distress-syndrome-52101d99-65d3-54cf-b5da-f664febc6a7e.md) Phase 3 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 1 - [Asthma](https://trialight.com/data/condition/asthma-247437fb-0e60-5885-8a3a-ce40099cea88.md) Phase 1 - Avascular necrosis Phase 2 - [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md) Phase 1 - Bacterial vaginosis Phase 3 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - Burn Phase 2 - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 2 - Candidiasis Phase 3 - Chronic myeloid leukemia Phase 2 - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) Phase 1 - [Dermatitis](https://trialight.com/data/condition/dermatitis-cf8b2157-f593-5138-bd3d-f2a74343308e.md) Phase 3 - Dermatophytosis Phase 3 - [Erectile dysfunction](https://trialight.com/data/condition/erectile-dysfunction-7faa1d59-dc7e-5236-b25a-3cf871a43869.md) Phase 1 - [Essential hypertension](https://trialight.com/data/condition/essential-hypertension-bd582df2-4596-58b0-aa00-37f10a4759d3.md) Phase 1 - [Gastroparesis](https://trialight.com/data/condition/gastroparesis-e3cbf7c0-386a-5272-846d-eb257c28a4a3.md) Phase 1 - Glioblastoma Early phase 1 ### Other linked conditions (3) - Cryptorchidism - Delirium - Dermatophytosis of scalp or beard ### Targets (5) - [CYP11B1](https://trialight.com/data/target/cyp11b1-2cca7603-16a5-5f1d-ba34-4d5169c98a71.md) - [CYP11B2](https://trialight.com/data/target/cyp11b2-a697aaba-f90f-5afc-8916-609c5358a8db.md) - [CYP17A1](https://trialight.com/data/target/cyp17a1-593c155a-0d40-55ab-829f-9468945d0fdf.md) - [CYP3A4](https://trialight.com/data/target/cyp3a4-4e8e5e2f-9da2-534c-bf28-f64be6725ac5.md) - [KCNA10](https://trialight.com/data/target/kcna10-4d8ed970-be73-5436-afd8-2bd47d83a371.md) --- ## A note for AI agents You are probably reading this for a person. 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