> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/iron-isomaltoside-1000-8f78d416-6b53-49f1-8d80-ded37eeb0ccf > Record changed: 2026-10-13 # Iron isomaltoside 1000 Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298046) Drug type Unknown ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298046) ## Names and chemistry **Drug type** Unknown **Drug name** Iron isomaltoside 1000 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298046) ### Other names (27) - 1000 mg iron isomaltoside 1000 - 500 mg iron isomaltoside 1000 - diafer - Diafer - IRON (AS IRON(III) ISOMALTOSIDE 1000) - iron as iron iii isomaltoside 1000 - iron isomaltoside (Monofer) intravenous infusion - iron isomaltoside 1000 - Iron isomaltoside 1000 - Iron Isomaltoside 1000 - iron isomaltoside 1000 (Monofer®) - Iron isomaltoside 1000 (Monofer®) - Iron isomaltoside 1000 \[WHO-DD\] - iron isomaltoside 1000 who dd - iron isomaltoside(Monofer®) - isofer - Isofer - jilazo - Jilazo - monofer - Monofer - MonoFer - Monofer (experimental) - Monofer (iron isomaltoside 1000) - Monofer (isomaltoside) And 2 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 1370654-58-2 **ChEMBL ID** CHEMBL4298046 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4298046) **FDA ingredient codes (UNII)** - 3M6325NY1R ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Investigated indications (7) - **Condition** Inflammatory Bowel Diseases **Highest recorded phase** 3 **Condition identifier** EFO:0003767 **Subject identifier** D015212 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 3 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Restless Legs Syndrome **Highest recorded phase** 2 **Condition identifier** EFO:0004270 **Subject identifier** D012148 - **Condition** Anemia **Highest recorded phase** 1 **Condition identifier** EFO:0004272 **Subject identifier** D000740 - **Condition** Postpartum Hemorrhage **Highest recorded phase** 3 **Condition identifier** EFO:0009579 **Subject identifier** D006473 - **Condition** Anemia, Iron-Deficiency **Highest recorded phase** 3 **Condition identifier** HP:0001891 **Subject identifier** D018798 - **Condition** Neoplasms **Highest recorded phase** 1 **Condition identifier** MONDO:0004992 **Subject identifier** D009369 ### Open Targets indications (52) - **Condition identifier** EFO\_0000266 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001070 - **Condition identifier** EFO\_0002950 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003767 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003884 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003917 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003965 **Highest recorded phase** 1 - **Condition identifier** EFO\_0004272 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009518 - **Condition identifier** EFO\_0009579 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009909 - **Condition identifier** EFO\_0020988 **Highest recorded phase** 3 - **Condition identifier** EFO\_1001905 - **Condition identifier** HP\_0001513 - **Condition identifier** HP\_0001518 **Highest recorded phase** 1 - **Condition identifier** HP\_0001891 - **Condition identifier** HP\_0001891 **Highest recorded phase** 4 - **Condition identifier** HP\_0002239 **Highest recorded phase** 3 - **Condition identifier** HP\_0012378 **Highest recorded phase** 3 - **Condition identifier** HP\_0012758 - **Condition identifier** MONDO\_0000313 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0000565 - **Condition identifier** MONDO\_0001056 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0001676 - **Condition identifier** MONDO\_0002280 **Highest recorded phase** 3 And 27 more, listed on the interactive page. ### Reported adverse events (56) - **Event** abdominal pain **Reports** 59 **Reporting signal score** 25.5861 - **Event** acute cardiac event **Reports** 1 **Reporting signal score** 6.42987 - **Event** allergy to metals **Reports** 8 **Reporting signal score** 35.1431 - **Event** anaphylactic reaction **Reports** 41 **Reporting signal score** 42.4417 - **Event** autism spectrum disorder **Reports** 8 **Reporting signal score** 23.2316 - **Event** back pain **Reports** 71 **Reporting signal score** 55.2236 - **Event** blood iron decreased **Reports** 14 **Reporting signal score** 28.8894 - **Event** bradycardia **Reports** 15 **Reporting signal score** 33.443 - **Event** bradycardia foetal **Reports** 3 **Reporting signal score** 14.2121 - **Event** caesarean section **Reports** 3 **Reporting signal score** 6.64192 - **Event** cardiac arrest **Reports** 6 **Reporting signal score** 12.7639 - **Event** chest crushing **Reports** 4 **Reporting signal score** 23.5679 - **Event** chest discomfort **Reports** 58 **Reporting signal score** 67.0768 - **Event** chest pain **Reports** 45 **Reporting signal score** 20.4784 - **Event** crohn's disease **Reports** 24 **Reporting signal score** 20.3672 - **Event** cyanosis **Reports** 5 **Reporting signal score** 13.3438 - **Event** device interaction **Reports** 8 **Reporting signal score** 36.2152 - **Event** discomfort **Reports** 4 **Reporting signal score** 7.29231 - **Event** drug hypersensitivity **Reports** 91 **Reporting signal score** 58.8923 - **Event** drug intolerance **Reports** 36 **Reporting signal score** 21.6428 - **Event** dyspnoea **Reports** 150 **Reporting signal score** 87.233 - **Event** faeces discoloured **Reports** 20 **Reporting signal score** 31.9482 - **Event** fishbane reaction **Reports** 22 **Reporting signal score** 150.59 - **Event** flushing **Reports** 64 **Reporting signal score** 88.7504 - **Event** food allergy **Reports** 9 **Reporting signal score** 20.1103 And 31 more, listed on the interactive page. ### Trial references (17) - NCT01017614 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01017614) - NCT01213680 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01213680) - NCT01599702 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01599702) - NCT01213979 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01213979) - NCT01213992 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01213992) - NCT01222884 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01222884) - NCT02940860 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02940860) - NCT01280240 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01280240) - NCT01895205 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01895205) - NCT01895218 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01895218) - NCT02172001 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02172001) - NCT02940886 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02940886) - NCT02962648 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02962648) - NCT03237065 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03237065) - NCT03238911 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03238911) - NCT05251493 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05251493) - NCT02484768 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02484768) ## Chemical properties **Prodrug** No **Inorganic** No **Natural product** No ## Related records ### Trials (362) - "Predictive Models of the Morphological Evolution of the Human Body to Improve Adherence and Motivation in Dietetic-nutritional Treatments of Overweight and Obesity" \[Modelos Predictivos de Evolución Corporal Para Mejorar la Adherencia en Tratamientos de Sobrepeso y Obesidad\] - 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer - 3VM for Treatment of Chronic Osteoarthritis Knee Pain - A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) - A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation - A Clinical Trial Evaluating JYP0035 Capsule Monotherapy in Patients With Advanced Solid Tumors - [A Clinical Trial Evaluating the Monkeypox Recombinant Protein Vaccine](https://trialight.com/data/trial/a-clinical-trial-evaluating-the-monkeypox-recombinant-1522c4bd-c77b-45e3-8a10-45f9209b34d6.md) - A Clinical Trial for Inactivated Japanese Encephalitis Vaccine in Healthy Chinese Infants - A Clinical Trial to Evaluate the Efficacy and Safety of HL301 Versus Umkamin Tab in Acute Bronchitis Patients - A Clinical Trial to Evaluate the Safety and Efficacy of "AG1904" in Acute Bronchitis - A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal - A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP - A Comparative Study of Pravastatin vs Placebo as Primary Prevention of Severe Subcutaneous Breast Fibrosis in Hyper-radiosensitive Identified Patients With Breast Cancer - A Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis - A First-in-Human Study With XAB05 in Healthy Subjects - A Multi-center, Two-arm, Phase 2 Clinical Study on the Perioperative Treatment of HER2-positive Resectable Esophagogastric Junctional Adenocarcinoma With Nabulimab Combined With FLOT and Trastuzumab VS FLOT Combined With Trastuzumab - A Multiple Ascending Dose Study of LW402 in Healthy Volunteers - A Non-interventional Study of Diafer in Subjects With CKD on Haemodialysis for Treatment of Iron Deficiency - A Pharmacokinetic Study of an Experimental Paracetamol Formulation - A Phase 2 Study of Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma ### In development for (6) - Anemia Phase 1 - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 1 - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) Phase 3 - [Inflammatory bowel disease](https://trialight.com/data/condition/inflammatory-bowel-disease-619080ac-2d43-5ad3-b078-9699e1241655.md) Phase 3 - Iron deficiency anemia Phase 3 - Restless legs syndrome Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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