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Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/inpegsomatropin-c32ce698-951f-4d34-8540-b95205257692 > Record changed: 2026-10-13 # Inpegsomatropin Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) Drug type Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) ## Names and chemistry **Drug type** Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) **Drug name** Inpegsomatropin Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) ### Other names (17) - inpegsomatropin - Inpegsomatropin - inpegsomatropin \[INN\] - Inpegsomatropin \[WHO-DD\] - inpegsomatropin injection - Inpegsomatropin Injection - inpegsomatropin inn - inpegsomatropin who dd - Inpegsomatropin-Injection - inpegsomatropina - Inpegsomatropina - inpegsomatropine - Inpegsomatropine - Recombinant human somatotropin (growth hormone, GH), conjugated to a multi-arm polyethylene glycol carrier molecule (somatotropin (human), produced by Pichia pastoris, non-glycosylated, N-terminal or N6.Lys mono-substituted with one (2-\[ω-methoxypoly(oxyethylene)-α-yl\]-N-{2-\[ω-methoxypoly(oxyethylene)-α-yl\]ethyl}acetamido)acetyl group (\~40 kDa) - recombinant human somatotropin growth hormone gh conjugated to a multi arm polyethylene glycol carrier molecule somatotropin human produced by pichia pastoris non glycosylated n terminal or n6 lys mono substituted with one 2 ω methoxypoly oxyethylene α yl n 2 ω methoxypoly oxyethylene α yl ethyl acetamido acetyl group 40 kda - Somatotropin (recombinant human), 1(38,70,140,145 or 158)-amide with α-hydro-ω-methoxypoly(oxy-1,2-ethanediyl) ether with N-(2-hydroxyacetyl)-N-(2-hydroxyethyl)glycine (2:1) - somatotropin recombinant human 1 38 70 140 145 or 158 amide with α hydro ω methoxypoly oxy 1 2 ethanediyl ether with n 2 hydroxyacetyl n 2 hydroxyethyl glycine 2 1 ## Identifiers **CAS registry numbers** - 2656386-75-1 **ChEMBL ID** CHEMBL5314747 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314747) **FDA ingredient codes (UNII)** - NUB86ZJ8XT ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-peg-; -pin; -trop- ### Open Targets indications - **Condition identifier** HP\_0004322 **Highest recorded phase** 3 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ### Sequences (3) - **Component** Sequence **Type** Protein **Sequence** FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF - **Component** Sequence **Type** Protein **Sequence** FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF - **Component** Disulfide bridges **Sequence** 53-165 $ 182-189 ## Related records ### Trials (1,754) - \[18F\]FLOR (FC303) PET/CT Imaging in Patients With Prostate Cancer - 124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis - 18F-ASIS PET/CT Imaging of Tissue Factor Expression In Patients With Primary and Metastastic Cancer - 18F-PBR06/Total Body PET Imaging in Patients With STEMI - 3D1015 Injection for Patients With mCRPC - 4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP) - 68Ga-DOTATATE PET-CTA Imaging for the Early Detection of Progressing Coronary Atherosclerosis - 68Ga-GP-01 Injection in Solid Tumors Participants - 99Tc-MDP for Thyroid-Associated Ophthalmopathy - A 1/2 Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ASKB589 in Patients With Locally Advanced or Metastatic Solid Tumors - [A Bioequivalence Study of Two Different Dosage Form of Genakumab](https://trialight.com/data/trial/a-bioequivalence-study-of-two-different-dosage-form-of-03d29337-07b6-4f97-a6fb-9b6ba6d15e0f.md) - A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients - A Clinical Study Comparing the Relative Bioavailability and Safety of SHR-3167 Injection - A Clinical Study Evaluating HAIC Combined With Iparomlimab and Tuvonralimab Injection Plus Bevacizumab in Patients With Initially Potentially Resectable Hepatocellular Carcinoma (ITBHaic Study) - A Clinical Study Evaluating the Diagnostic Performance and Safety of PET for the Deposition of Aβ Plaques in the Brain of Participants With Normal Cognitive Function, MCI and AD Using \[18F\]Fluorbetazine Injection - A Clinical Study Evaluating the Efficacy and Safety of HRS-7249 in Treating Patients With Hyperlipidemia - A Clinical Study Evaluating the Efficacy and Safety of SHR-1139 Injection in Adult Patients With Ulcerative Pyoderma Gangrenosum - A Clinical Study Evaluating the Efficacy and Safety of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis - A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. - A Clinical Study Evaluating the Safety and Efficacy of BioTTT001 in Patients With Malignant Solid Tumors --- ## A note for AI agents You are probably reading this for a person. 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