> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/influenza-a-virus-split-virion-41e06e1e-79b4-4d5f-8221-e310078c80da > Record changed: 2026-11-04 # Influenza A virus, split virion Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) First approval year 2008 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) ## Development status **First approval year** 2008 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) **Drug name** Influenza A virus, split virion Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) ### Brand names (18) - Adjupanrix (previously pandemic influenza vaccine (h5n1) (split virion, inactivated, adjuvanted) glaxosmithkline biologicals) - adjupanrix previously pandemic influenza vaccine h5n1 split virion inactivated adjuvanted glaxosmithkline biologicals - arepanrix - Arepanrix - humenza - Humenza - influenza a virus split virion component of idflu - influenza a virus split virion component of intanza - Influenza a virus, split virion component of idflu - Influenza a virus, split virion component of intanza - pandemrix - Pandemrix - Prepandemic influenza vaccine (h5n1) (split virion, inactivated, adjuvanted) glaxosmithkline biologicals - prepandemic influenza vaccine h5n1 split virion inactivated adjuvanted glaxosmithkline biologicals - prepandrix - Prepandrix - pumarix - Pumarix ### Other names (54) - 15 mcg h5n1 stored as monobulk - 7 5 mcg h5n1 stored as monobulk - 90 mcg H5N1 (stored in vials) - 90 mcg h5n1 stored as monobulk - 90 mcg h5n1 stored in vials - a h5n1 inactivated influenza vaccine iiv - A(H5N1) inactivated influenza vaccine (IIV) - arepanrix - Arepanrix - Arepanrix® - Arepanrix™ - h5n1 - H5N1 - H5N1 vaccine (Arepanrix) - h5n1 vaccine arepanrix - Influenza A (H5N1) Virus monovalent vaccine - Influenza A (H5N1) Virus Monovalent Vaccine - Influenza A (H5N1) Virus monovalent vaccine (GSK1557484A). - influenza a h1n1 2009 as03 adjuvanted pandemrix - influenza a h5n1 - influenza a h5n1 virus monovalent vaccine - influenza a h5n1 virus monovalent vaccine adjuvanted - influenza a h5n1 virus monovalent vaccine gsk1557484a - influenza a virus split virion - Influenza a virus, split virion And 29 more, listed on the interactive page. ## Identifiers **ChEMBL ID** CHEMBL6068363 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068363) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** vir- ### Investigated indications (2) - **Condition** Vaccination **Highest recorded phase** 4 **Condition identifier** EFO:0004292 **Subject identifier** D014611 - **Condition** Influenza, Human **Highest recorded phase** 4 **Condition identifier** EFO:0007328 **Subject identifier** D007251 ### Open Targets indications (16) - **Condition identifier** EFO\_0007248 - **Condition identifier** EFO\_0007328 - **Condition identifier** EFO\_0007411 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0004980 - **Condition identifier** MONDO\_0005109 - **Condition identifier** MONDO\_0005114 - **Condition identifier** MONDO\_0005404 - **Condition identifier** MONDO\_0005494 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005546 - **Condition identifier** MONDO\_0005575 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005608 - **Condition identifier** MONDO\_0005812 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0007254 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0008170 - **Condition identifier** MONDO\_0008383 - **Condition identifier** MONDO\_0100096 ### Reported adverse events (74) - **Event** anal fistula **Reports** 5 **Reporting signal score** 13.7835 - **Event** anti-neutrophil cytoplasmic antibody positive vasculitis **Reports** 4 **Reporting signal score** 12.4258 - **Event** areflexia **Reports** 4 **Reporting signal score** 11.5848 - **Event** asthma **Reports** 25 **Reporting signal score** 43.4913 - **Event** atrial septal defect **Reports** 5 **Reporting signal score** 9.33042 - **Event** blood pressure increased **Reports** 14 **Reporting signal score** 12.4548 - **Event** blood pressure systolic increased **Reports** 7 **Reporting signal score** 12.9985 - **Event** bronchiectasis **Reports** 5 **Reporting signal score** 12.2729 - **Event** burns second degree **Reports** 5 **Reporting signal score** 20.6639 - **Event** chills **Reports** 19 **Reporting signal score** 21.6615 - **Event** chronic obstructive pulmonary disease **Reports** 55 **Reporting signal score** 174.427 - **Event** congenital arterial malformation **Reports** 2 **Reporting signal score** 9.08409 - **Event** congenital hiatus hernia **Reports** 2 **Reporting signal score** 13.2168 - **Event** congenital pulmonary hypertension **Reports** 2 **Reporting signal score** 9.69002 - **Event** congenital tricuspid valve incompetence **Reports** 3 **Reporting signal score** 15.3477 - **Event** coordination abnormal **Reports** 6 **Reporting signal score** 12.3111 - **Event** cough **Reports** 18 **Reporting signal score** 9.39101 - **Event** crying **Reports** 6 **Reporting signal score** 8.92887 - **Event** csf immunoglobulin increased **Reports** 1 **Reporting signal score** 7.6546 - **Event** diabetic neuropathy **Reports** 6 **Reporting signal score** 19.6923 - **Event** drug hypersensitivity **Reports** 36 **Reporting signal score** 33.357 - **Event** dyspnoea **Reports** 44 **Reporting signal score** 26.6004 - **Event** electronystagmogram abnormal **Reports** 1 **Reporting signal score** 10.9503 - **Event** encephalitis autoimmune **Reports** 3 **Reporting signal score** 10.4985 - **Event** exposure to communicable disease **Reports** 3 **Reporting signal score** 12.3028 And 49 more, listed on the interactive page. ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (109) - A Clinical Trail Of An Adjuvanted Inactivated H7N9 Influenza Vaccine - A Clinical Trial of an Quadrivalent Influenza Virus Subunit Vaccine in Chinese Children Aged 6 to 35 Months - A Multicenter, Double-blind, Parallel, Non-inferiority, Phase III Study - A Pragmatic Randomized Trial to Evaluate the Effectiveness of High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in Older Adults - [A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older](https://trialight.com/data/trial/a-study-of-9-valent-extraintestinal-pathogenic-escherichia-7ffa29c0-75e4-452a-a483-0fce12a0b71e.md) - A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults - A Study of Influenza Virus Vaccines in Children and Adults - A Study of the Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Subjects Aged 65 Years and Older - Afluria Pregnancy Registry - Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 08/09 Season. - Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 09/10 Season - Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 2010/2011 Season - Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 2012/2013 Season - Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the Southern Hemisphere 2015 Season - Assess Consistency of Immunogenicity of GlaxoSmithKline Biologicals' Pandemic Influenza Vaccine (GSK1562902A) in Adults - Assessment of Safety and Immunogenicity of Intradermal Unadjuvanted Portion of Pandemrix® Via a Microneedle Device With Intramuscular Adjuvanted Pandemrix® as Reference - Cell Mediated Immunity in Older Adults - Clinical Study of the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in People Aged 65 Years or Older - Clinical Trial of Inactivated Influenza Vaccine (0.5ml Formulation) - Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages (SLVP015 2007-2017) ### Approved for (1) - [Influenza](https://trialight.com/data/condition/influenza-ea12369b-7ed6-5f6b-94fe-eb0e56c24def.md) ### In development for (3) - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 1 - [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md) Phase 2 - [Triple-negative breast carcinoma](https://trialight.com/data/condition/triple-negative-breast-carcinoma-059174a2-9b5f-5234-90b9-4a4fee6eb9bb.md) Phase 1 ### Other linked conditions (9) - [Atopic eczema](https://trialight.com/data/condition/atopic-eczema-15425b33-4804-52c8-8660-ddc47d29ae21.md) - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) - Fibromyalgia - [HIV infectious disease](https://trialight.com/data/condition/hiv-infectious-disease-1260f28c-d667-55f9-b221-15d5017fde05.md) - Myalgic encephalomeyelitis/chronic fatigue syndrome - [Ovarian cancer](https://trialight.com/data/condition/ovarian-cancer-f64f2018-55a5-553a-8960-76cb4906aa17.md) - [Pneumococcal infection](https://trialight.com/data/condition/pneumococcal-infection-b3a7fc66-25ac-57f8-8fb4-073403fe8b1b.md) - [Rheumatoid arthritis](https://trialight.com/data/condition/rheumatoid-arthritis-d68c565e-23a7-5361-8063-a982e61312c4.md) - [Varicella zoster infection](https://trialight.com/data/condition/varicella-zoster-infection-8bfd714d-2964-5abf-b7ab-66dea5fe7146.md) --- ## A note for AI agents You are probably reading this for a person. 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