> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/fusidate-sodium-c030b430-8388-4991-a143-1b23e74beb6a > Record changed: 2026-10-13 # Fusidate sodium Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) ## Development status **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) **Drug name** Fusidate sodium Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) **Molecular weight** 538.7 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) **Structure (SMILES)** CC(=O)O\[C@H\]1C\[C@@\]2(C)\[C@@H\](C\[C@@H\](O)\[C@H\]3\[C@@\]4(C)CC\[C@@H\](O)\[C@@H\](C)\[C@@H\]4CC\[C@@\]32C)/C1=C(\\CCC=C(C)C)C(=O)\[O-\].\[Na+\] Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) ### Brand names (2) - fucidine - Fucidine ### Other names (36) - fucidin - Fucidin - fucidin leo - Fucidin leo - fucidin ointment - Fucidin Ointment - Fucidin® cream - fusidate sodium - Fusidate sodium - Fusidate sodium \[USAN\] - Fusidate sodium \[WHO-DD\] - fusidate sodium usan - fusidate sodium who dd - fusidic acid sodium salt - Fusidic acid sodium salt - Fusidic acid sodium salt \[MI\] - fusidic acid sodium salt mi - Fusidic acid, sodium salt - sodium 3α 11α 16β trihydroxy 29 nor 8α 9β 13α 14β dammara 17 20 24 dien 21 oate 16 acetate - Sodium 3α,11α,16β-trihydroxy-29-nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oate 16-acetate - sodium fusidate - Sodium fusidate - Sodium Fusidate - Sodium fusidate \[EP MONOGRAPH\] - Sodium fusidate \[JAN\] And 11 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 751-94-0 **ChEMBL ID** CHEMBL1256987 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) **InChIKey** HJHVQCXHVMGZNC-JCJNLNMISA-M Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1256987) **PubChem compound IDs** - 23672955 **RxNorm IDs (RxCUI)** - 9874 **FDA ingredient codes (UNII)** - J7P3696BCQ ## Regulatory information ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No ## Pharmacology ### Drug classification **Pharmacology name** fusidic acid **Type** Synthetic organic ### Mechanisms of action - **Mechanism** Elongation factor G inhibitor **Action type** Inhibitor **Target** Elongation factor G **Protein identifier** P68790 ### Open Targets mechanisms - **Mechanism** Elongation factor G inhibitor **Action type** Inhibitor **Target** Elongation factor G ### Investigated indications (3) - **Condition** Infections **Highest recorded phase** 3 **Condition identifier** EFO:0000544 **Subject identifier** D007239 - **Condition** Diabetic Foot **Highest recorded phase** 0.5 **Condition identifier** EFO:1001459 **Subject identifier** D017719 - **Condition** Cystic Fibrosis **Highest recorded phase** 2 **Condition identifier** MONDO:0009061 **Subject identifier** D003550 ### Open Targets indications (6) - **Condition identifier** EFO\_0000544 **Highest recorded phase** 3 - **Condition identifier** EFO\_1001459 - **Condition identifier** HP\_0000964 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0004980 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0009061 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0021178 ### Reported adverse events (47) - **Event** acute generalised exanthematous pustulosis **Reports** 3 **Reporting signal score** 6.59175 - **Event** acute kidney injury **Reports** 8 **Reporting signal score** 6.70328 - **Event** agranulocytosis **Reports** 4 **Reporting signal score** 7.04195 - **Event** bilirubin conjugated increased **Reports** 3 **Reporting signal score** 10.2867 - **Event** blood creatine phosphokinase increased **Reports** 7 **Reporting signal score** 12.3359 - **Event** burns third degree **Reports** 3 **Reporting signal score** 15.8631 - **Event** cataract **Reports** 12 **Reporting signal score** 30.5468 - **Event** cholestasis **Reports** 15 **Reporting signal score** 45.4906 - **Event** circulatory failure neonatal **Reports** 1 **Reporting signal score** 6.84719 - **Event** dermatitis atopic **Reports** 12 **Reporting signal score** 54.7154 - **Event** drug interaction **Reports** 13 **Reporting signal score** 13.4645 - **Event** dyspepsia **Reports** 13 **Reporting signal score** 28.2904 - **Event** dysphagia **Reports** 12 **Reporting signal score** 20.1081 - **Event** eczema **Reports** 5 **Reporting signal score** 10.6195 - **Event** eczema impetiginous **Reports** 1 **Reporting signal score** 6.19363 - **Event** eosinophilia **Reports** 8 **Reporting signal score** 20.4137 - **Event** fat necrosis **Reports** 4 **Reporting signal score** 20.3335 - **Event** flat feet **Reports** 1 **Reporting signal score** 7.01419 - **Event** gastroenteritis **Reports** 12 **Reporting signal score** 38.7715 - **Event** gastrointestinal motility disorder **Reports** 3 **Reporting signal score** 10.0608 - **Event** haematoma **Reports** 5 **Reporting signal score** 9.18021 - **Event** immune reconstitution inflammatory syndrome **Reports** 5 **Reporting signal score** 15.645 - **Event** jaundice **Reports** 13 **Reporting signal score** 34.0678 - **Event** metabolic acidosis **Reports** 4 **Reporting signal score** 6.17358 - **Event** muscular weakness **Reports** 14 **Reporting signal score** 25.4268 And 22 more, listed on the interactive page. ### Trial references (4) - NCT02569541 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02569541) - NCT02570490 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02570490) - NCT03816618 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03816618) - NCT05641298 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05641298) ## Chemical properties **Hydrogen bond acceptors** 5 **Hydrogen bond donors** 3 **Polar surface area** 104.06 **Calculated partition coefficient (ALogP)** 5.67 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 2 **Rotatable bonds** 5 **Heavy atoms** 38 **Molecular formula** C31H47NaO6 **Monoisotopic mass** 538.32703350 **Natural product** Yes ## Evidence counts **Recorded assays** 547 **Active assays** 9 ### Active assay types (2) - Confirmatory - Screening ## Pharmacologic actions - Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. - Protein Synthesis Inhibitors Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. ## Related records ### Trials (28) - A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis - A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA) - A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID) - Chronic Pain Risk Associated With Menstrual Period Pain - Dose-Ranging Study of Quadrivalent Human Papillomavirus (HPV) (Types 6,11,16,18) L1 Virus-Like Particle (VLP) Vaccine (V501-007)(COMPLETED) - Effectiveness of Sodium Fusidate Ointment Compared to Petrolatum for Wound Healing Following Cauterization - Efficacy and Safety of Fucicort® Lipid Cream Compared to Combination Treatment With Fucidin® Cream Followed by Betamethasone (Lianbang Beisong®) Cream and Fucicort® Lipid Cream Vehicle in Clinically Infected Atopic Dermatitis/Eczema - Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema - Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity - Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity - Efficacy and Safety Study of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Combination Therapy in Patients With Hypertension Not Controlled With Olmesartan Medoxomil and Hydrochlorothiazide Combination Therapy - Fucidin® Cream in the Treatment of Impetigo - Fuzeon (Enfuvirtide) Early Access Program for Patients With HIV-1 Infection - Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and Hypercholesterolemia - Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency - Oral Contraceptive (OC) Estrogen Dose and Breast Proliferation - Oral Sodium Fusidate (CEM-102) for the Treatment of Staphylococcal Bone or Joint Infections - Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections - Safety and Efficacy of Inhaled OligoG CF-5/20 for the Treatment Cystic Fibrosis - Safety and Immunogenicity of a Group B Streptococcus Vaccine in Non Pregnant and Pregnant Women 18-40 Years of Age ### In development for (1) - [Cystic fibrosis](https://trialight.com/data/condition/cystic-fibrosis-6f9870eb-6ebc-5bec-a50b-34b0b323a7c3.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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