> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/fludeoxyglucose-f-18-93dd95bf-cfbc-4452-b0ff-9cc0f4edc6ee > Record changed: 2026-10-13 # Fludeoxyglucose F 18 Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) First approval year 1994 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) ## Development status **First approval year** 1994 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **Drug name** Fludeoxyglucose F 18 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **Molecular weight** 181.15 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **Structure (SMILES)** OC\[C@H\]1OC(O)\[C@H\](\[18F\])\[C@@H\](O)\[C@@H\]1O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) ### Brand names (2) - fludeoxyglucose f18 - Fludeoxyglucose f18 ### Other names (78) - (18f)-fdg - (18f)-fluorodeoxyglucose - (18f)fdg - (18f)fluoro-2-deoxyglucose - (18f)fluorodeoxyglucose - \[18-F\] Fluorodeoxyglucose (FDG) - \[18F\]-FDG - \[18F\]-Fluorodeoxyglucose - \[18F\]FDG - \[18F\]fluoro-2-deoxy-D-glucose (FDG) - \[18F\]fluorodeoxyglucose - \[18F\]Fluorodeoxyglucose - 18 f fdg - 18 f fluorodeoxyglucose fdg - 18 fdg - 18-f fdg - 18-F FDG - 18-FDG - 18f - 18f fdg - 18f fluoro 2 deoxyglucose - 18f fluorodeoxyglucose - 18F- fluorodeoxyglucose - 18F-deoxyglucose (FDG) - 18f-fdg And 53 more, listed on the interactive page. ## Identifiers **ATC classification codes** - V09IX04 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **ChEMBL ID** CHEMBL2030434 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **InChIKey** ZCXUVYAZINUVJD-GLCXRVCCSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2030434) **PubChem compound IDs** - 11469444 **RxNorm IDs (RxCUI)** - 1362737 ## Regulatory information ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification #### Administration routes - Parenteral ### Investigated indications (52) - **Condition** Carcinoma, Hepatocellular **Highest recorded phase** 2 **Condition identifier** EFO:0000182 **Subject identifier** D006528 - **Condition** Hodgkin Disease **Highest recorded phase** 2 **Condition identifier** EFO:0000183 **Subject identifier** D006689 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000196 **Subject identifier** D011471 - **Condition** Leukemia, Myeloid, Acute **Highest recorded phase** 3 **Condition identifier** EFO:0000222 **Subject identifier** D015470 - **Condition** Leukemia, Promyelocytic, Acute **Highest recorded phase** 1 **Condition identifier** EFO:0000224 **Subject identifier** D015473 - **Condition** Breast Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000305 **Subject identifier** D001943 - **Condition** Cardiovascular Diseases **Highest recorded phase** 0.5 **Condition identifier** EFO:0000319 **Subject identifier** D002318 - **Condition** Carcinoma, Renal Cell **Highest recorded phase** 1 **Condition identifier** EFO:0000349 **Subject identifier** D002292 - **Condition** Adenocarcinoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000501 **Subject identifier** D018263 - **Condition** Stomach Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000503 **Subject identifier** D013274 - **Condition** Glioblastoma **Highest recorded phase** 2 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Lymphoma **Highest recorded phase** 3 **Condition identifier** EFO:0000574 **Subject identifier** D008223 - **Condition** Mesothelioma **Highest recorded phase** 1 **Condition identifier** EFO:0000588 **Subject identifier** D008654 - **Condition** Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Thyroid Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000641 **Subject identifier** D013964 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Arthritis, Rheumatoid **Highest recorded phase** 1 **Condition identifier** EFO:0000685 **Subject identifier** D001172 - **Condition** Sarcoma **Highest recorded phase** 2 **Condition identifier** EFO:0000691 **Subject identifier** D012509 - **Condition** Melanoma **Highest recorded phase** 1 **Condition identifier** EFO:0000756 **Subject identifier** D008545 - **Condition** Idiopathic Pulmonary Fibrosis **Highest recorded phase** 1 **Condition identifier** EFO:0000768 **Subject identifier** D054990 - **Condition** Multiple Myeloma **Highest recorded phase** 1 **Condition identifier** EFO:0001378 **Subject identifier** D009101 - **Condition** Uterine Cervical Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0001416 **Subject identifier** D002583 - **Condition** Hematologic Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0001642 **Subject identifier** D019337 - **Condition** Prostatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0001663 **Subject identifier** D011471 - **Condition** Pancreatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0002618 **Subject identifier** D010190 And 27 more, listed on the interactive page. ### Open Targets indications (17) - **Condition identifier** EFO\_0000319 - **Condition identifier** EFO\_0000756 - **Condition identifier** EFO\_0001416 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003060 - **Condition identifier** HP\_0001082 - **Condition identifier** MONDO\_0002367 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0002974 - **Condition identifier** MONDO\_0004975 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005005 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005192 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005233 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0006047 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0007254 - **Condition identifier** MONDO\_0008667 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0008903 - **Condition identifier** MONDO\_0016698 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0018907 **Highest recorded phase** 2 ### Reported adverse events (6) - **Event** bone lesion **Reports** 2 **Reporting signal score** 9.3195 - **Event** glioblastoma multiforme **Reports** 2 **Reporting signal score** 12.8687 - **Event** hyperproteinaemia **Reports** 2 **Reporting signal score** 14.788 - **Event** neuroendocrine tumour **Reports** 2 **Reporting signal score** 11.8532 - **Event** occupational exposure to radiation **Reports** 2 **Reporting signal score** 19.7811 - **Event** second primary malignancy **Reports** 2 **Reporting signal score** 7.64211 ### Trial references (68) - NCT00043979 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00043979) - NCT04457258 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04457258) - NCT00062374 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00062374) - NCT00070239 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00070239) - NCT00085293 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00085293) - NCT00095693 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00095693) - NCT00729157 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00729157) - NCT00088374 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00088374) - NCT00227539 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00227539) - NCT00852644 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00852644) - NCT00953459 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00953459) - NCT03493789 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03493789) - NCT05501665 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05501665) - NCT00375830 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00375830) - NCT00708045 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00708045) - NCT01697527 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01697527) - NCT00433459 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00433459) - NCT01132807 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01132807) - NCT01359592 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01359592) - NCT00453362 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00453362) - NCT00923273 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00923273) - NCT01507428 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01507428) - NCT01731626 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01731626) - NCT02773238 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02773238) - NCT04214262 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04214262) And 43 more, listed on the interactive page. ## Dosing **Dose** 5-10 mCi **Route** Intravenous **How often** As needed ### Conditions of use (3) - Acquire images 30 to 100 minutes from injection - Initiate imaging within 40 minutes - Use within 12 hours from the EOS ## Chemical properties **Hydrogen bond acceptors** 5 **Hydrogen bond donors** 4 **Polar surface area** 90.15 **Calculated partition coefficient (ALogP)** \-2.24 **Calculated partition coefficient (XLogP)** \-1.6 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 1 **Heavy atoms** 12 **Molecular formula** C6H11FO5 **Monoisotopic mass** 181.061586 **Natural product** No ## Evidence counts **Recorded assays** 61 **Active assays** 0 ## Related records ### Trials (576) - \[18F\]-Fluoro-2-Deoxy-D-Glucose and -\[18F\] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer - \[68Ga\]Ga-PentixaFor-PET Imaging for Staging of Marginal Zone Lymphoma - 177Lutetium-octreotate Treatment Prediction Using Multimodality Imaging in Refractory NETs - 17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease - 18F-AlF-FAPi-04 PET/CT Imaging in Patients With Solid Tumor - 18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer - 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer - 18F-deoxyglucose (FDG) PET-CMD - 18F-FAPI PET Imaging in Pancreatic Adenocarcinoma - 18F-FDG PET/CT for IgG4-Related Disease - 18F-Fibroblast Activation Protein Inhibitor (\[18F\]FAPI-74) PET Imaging for Cancer Detection - 18F-FLT PET Imaging in Patients With Advanced Melanoma - 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy - 18F-FSPG PET/CT for Cancer Patients on Therapy - 18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules - 5T4 Targeting Nanobody Probe for PET Imaging in Solid Tumors - 68Ga-DOTA-NI-FAPI04 PET/CT in Patients With Various Types of Cancer - 68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy - 68Ga-FAPI-Biotin PET/CT in Patients With Various Types of Cancer - 68Ga-FAPI-RGD PET/CT Imaging in the Lung Cancer Patients ### In development for (52) - [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 3 - Acute promyelocytic leukemia Phase 1 - Adult glioblastoma Phase 2 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 1 - Angiosarcoma Phase 2 - Brain cancer Phase 1 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - Breast carcinoma Phase 2 - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 2 - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) Early phase 1 - [Cervical adenocarcinoma](https://trialight.com/data/condition/cervical-adenocarcinoma-013a4346-286c-5c50-bd25-66fde59ac6a0.md) Phase 2 - [Cervical cancer](https://trialight.com/data/condition/cervical-cancer-10fb8f6c-5aac-5281-8f06-7238adeec443.md) Phase 2 - Classic Hodgkin lymphoma Phase 2 - [Clear cell renal carcinoma](https://trialight.com/data/condition/clear-cell-renal-carcinoma-789eee25-ec64-5771-9b7d-d19544781b11.md) Phase 1 - Digestive system neuroendocrine neoplasm Phase 2 - Exocrine pancreatic carcinoma Phase 2 - [Follicular lymphoma](https://trialight.com/data/condition/follicular-lymphoma-88de1ce9-ab0e-5d65-85c4-45a681fa2931.md) Phase 2 - [Gastric adenocarcinoma](https://trialight.com/data/condition/gastric-adenocarcinoma-6bb74a55-7ba6-53e3-a113-22296a84d6ae.md) Phase 2 - Glioblastoma Phase 2 - Gliosarcoma Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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