> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/ferric-pyrophosphate-5f63223f-588b-41e9-a1db-6a4aaad9ec3b
> Record changed: 2026-10-13

# Ferric pyrophosphate

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297752)

Drug type

Small molecule

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/QK8899250F)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297752)

## Names and chemistry

**Drug type**

Small molecule

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/QK8899250F)

**Drug name**

Ferric pyrophosphate

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297752)

**Structure (SMILES)**

O(P(=O)(\[O-\])\[O-\])P(\[O-\])(=O)\[O-\].\[Fe+3\].O(P(=O)(\[O-\])\[O-\])P(\[O-\])(=O)\[O-\].O(P(=O)(\[O-\])\[O-\])P(\[O-\])(=O)\[O-\].\[Fe+3\].\[Fe+3\].\[Fe+3\]

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/QK8899250F)

### Other names (20)

- diphosphoric acid iron 3 salt 3 4
- DIPHOSPHORIC ACID IRON(3+) SALT (3:4)
- ferric pyrophosphate
- Ferric pyrophosphate
- FERRIC PYROPHOSPHATE \[FCC\]
- FERRIC PYROPHOSPHATE \[HSDB\]
- FERRIC PYROPHOSPHATE \[MART.\]
- FERRIC PYROPHOSPHATE \[MI\]
- FERRIC PYROPHOSPHATE \[VANDF\]
- Ferric pyrophosphate \[WHO-DD\]
- ferric pyrophosphate fcc
- ferric pyrophosphate hsdb
- ferric pyrophosphate mart
- ferric pyrophosphate mi
- ferric pyrophosphate vandf
- ferric pyrophosphate who dd
- Iron (as pyrophosphate)
- iron as pyrophosphate
- iron iii pyrophosphate
- Iron(iii) pyrophosphate

## Identifiers

**CAS registry numbers**

- 10058-44-3

**ChEMBL ID**

CHEMBL4297752

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297752)

**InChIKey**

CADNYOZXMIKYPR-UHFFFAOYSA-B

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/QK8899250F)

**PubChem compound IDs**

- 24877

**RxNorm IDs (RxCUI)**

- 1607976

**FDA ingredient codes (UNII)**

- QK8899250F

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (2)

- **Condition**  
Anemia

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0004272

**Subject identifier**  
D000740
- **Condition**  
Helicobacter Infections

**Highest recorded phase**  
1

**Condition identifier**  
EFO:1000961

**Subject identifier**  
D016481

### Open Targets indications (4)

- **Condition identifier**  
EFO\_0004272

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_1000961

**Highest recorded phase**  
1
- **Condition identifier**  
HP\_0001891

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0002280

**Highest recorded phase**  
3

### Reported adverse events

- **Event**  
medical device site joint inflammation

**Reports**  
1

**Reporting signal score**

12.0835

### Trial references (2)

- NCT00867867  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00867867)
- NCT05957328  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05957328)

## Chemical properties

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

No

**Heavy atoms**

31

**Monoisotopic mass**

745.47552

**Natural product**

No

## Evidence counts

**Recorded assays**

4

**Active assays**

0

## Related records

### Trials (121)

- .Patient Blood Management Program in Liver Transplantation
- 2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.
- A 30 Day Acute Efficacy and Safety Study of Chromium Picolinate + Biotin on Glycemic Control in Overweight or Obese Subjects With T2DM
- A Before and After Study Studying the Impact of an Analgesia Protocol After Discharge From Outpatient Surgery
- A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(3)
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386(3) 80/20/10mg
- A Multicenter RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML Patients
- [A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)](https://trialight.com/data/trial/a-phase-1-2-study-of-enzomenib-dsp-5336-in-patients-with-0e6145c8-1f49-44ed-a3c6-01e969666e64.md)
- A Phase 3 Study in Participants With Moderate to Severe Psoriasis
- A Phase 3b Study of Erythropoietin Drugs Using a Specified Dosing Algorithm in Patients With Chronic Kidney Disease on Hemodialysis
- A Randomized Study to Compare the Dosing Schedule of INFeD in Anemic Patients.
- A Randomized Trial of Oral Iron Therapy in Fibromyalgia
- A Study of Dengue Vaccine in Healthy Toddlers Aged 12 to 15 Months in the Philippines
- [A Study of Idazoxan in Healthy Participants](https://trialight.com/data/trial/a-study-of-idazoxan-in-healthy-participants-21158b5e-cf67-4c1a-b0e7-217c8e3a9e1a.md)
- A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in Children
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants
- A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease
- A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Nondialysis-Dependent Chronic Kidney Disease
- A Trial to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients with COPD

### In development for (2)

- Anemia Phase 3
- [Helicobacter pylori infectious disease](https://trialight.com/data/condition/helicobacter-pylori-infectious-disease-ff5903ca-758b-5979-a633-075499e2938b.md) Phase 1

---

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