> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/emrusolmin-2bdd273e-d76b-47e7-9a2e-836afc733bd8
> Record changed: 2026-10-13

# Emrusolmin

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

**Drug name**

Emrusolmin

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

**Molecular weight**

343.18

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

**Structure (SMILES)**

Brc1cccc(-c2cc(-c3ccc4c(c3)OCO4)n\[nH\]2)c1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

### Other names (13)

- anle 138b
- ANLE-138B
- anle138b
- Anle138b
- anle138b (TEV-56286)
- emrusolmin
- Emrusolmin
- emrusolmin \[INN\]
- emrusolmin inn
- emrusolmina
- Emrusolmina
- emrusolmine
- Emrusolmine

## Identifiers

**CAS registry numbers**

- 882697-00-9

**ChEMBL ID**

CHEMBL4748063

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

**InChIKey**

RCQIIBJSUWYYFU-UHFFFAOYSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4748063)

**PubChem compound IDs**

- 44608289

**FDA ingredient codes (UNII)**

- E7WRA77JET

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-solmin

### Investigated indications

- **Condition**  
Parkinson Disease

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0005180

**Subject identifier**  
D010300

### Open Targets indications (2)

- **Condition identifier**  
MONDO\_0005180

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0007803

**Highest recorded phase**  
2

### Trial references

- NCT04685265  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04685265)

## Chemical properties

**Hydrogen bond acceptors**

3

**Hydrogen bond donors**

1

**Polar surface area**

47.14

**Calculated partition coefficient (ALogP)**

4.23

**Calculated partition coefficient (XLogP)**

4

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

No

**Rule-of-five violations**

0

**Rotatable bonds**

2

**Heavy atoms**

21

**Molecular formula**

C16H11BrN2O2

**Monoisotopic mass**

342.00039

**Natural product**

Yes

## Evidence counts

**Recorded assays**

65

**Active assays**

1

### Active assay types

- Confirmatory

## Related records

### Trials (8)

- A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)
- A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects
- A Study to Assess New Formulations of TEV-56286
- A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson's Disease
- A Trial to Assess TEV-56286 at Different Doses in Healthy Participants
- [A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy](https://trialight.com/data/trial/a-trial-to-test-if-tev-56286-is-effective-for-treatment-of-ec4394e6-61e8-48a0-a337-468112f685be.md)
- An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
- Mass Balance Clinical Trial With TEV-56286

### In development for (1)

- [Parkinson disease](https://trialight.com/data/condition/parkinson-disease-a117728d-ad75-551b-9b20-fffa9a2305ac.md) Phase 1

---

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