> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/ecadotril-ffa9c9f5-de08-4e83-9f94-58f26c7104cf > Record changed: 2026-11-04 # Ecadotril Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) **Drug name** Ecadotril Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) **Molecular weight** 385.49 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) **Structure (SMILES)** CC(=O)SC\[C@@H\](Cc1ccccc1)C(=O)NCC(=O)OCc1ccccc1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) ### Other names (43) - bay y 7432 - BAY Y 7432 - BAY-Y-7432 - bp 1 02 - BP 1.02 - bp 102 - BP-1.02 - bp102 - BP102 - BP102 (B7-H3 CAR-T) - bp102 b7 h3 car t - bp102 injection - BP102 Injection - bp102 paclitaxel carboplatin - ecadotril - Ecadotril - ecadotril \[INN\] - ECADOTRIL \[USAN\] - ecadotril inn - ecadotril usan - ecadotrilo - Ecadotrilo - fh 006 shr 1316 bp102 - fh 006 shr 1316 bp102 cisplatin carboplatin - glycine n 2 acetylthio methyl 1 oxo 3 phenylpropyl phenylmethyl ester s And 18 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 112573-73-6 **ChEMBL ID** CHEMBL1516410 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) **InChIKey** ODUOJXZPIYUATO-LJQANCHMSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1516410) **PubChem compound IDs** - 60561 **FDA ingredient codes (UNII)** - 6XSR933SRK ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-tril ### Open Targets indications (4) - **Condition identifier** MONDO\_0005233 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005575 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0007254 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0008903 **Highest recorded phase** 2 ## Chemical properties **Hydrogen bond acceptors** 5 **Hydrogen bond donors** 1 **Polar surface area** 72.47 **Calculated partition coefficient (ALogP)** 2.98 **Calculated partition coefficient (XLogP)** 3.3 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 9 **Heavy atoms** 27 **Molecular formula** C21H23NO4S **Monoisotopic mass** 385.13477939 **Natural product** Yes ## Evidence counts **Recorded assays** 902 **Active assays** 34 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Antidiarrheals Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition. - Protease Inhibitors Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES). ## Related records ### Trials (14) - A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer - [A Phase II Clinical Study of HRS-7058 in Combination With Antitumor Drugs in Patients With Advanced Malignant Tumour](https://trialight.com/data/trial/a-phase-ii-clinical-study-of-hrs-7058-in-combination-with-66a0a475-49b9-4ee9-a803-aeb14e30897a.md) - A Study of SHR-1210 in Combination With BP102 in Subjects With Non-squamous NSCLC - A Study of SHR-1701 Plus Platinum-containing Chemotherapy With or Without BP102 (Bevacizumab) as First-line Treatment in Cervical Cancer - [A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC](https://trialight.com/data/trial/a-study-of-shr-1826-for-injection-in-combination-with-other-86919d29-2cc1-484a-9a76-bbb048399924.md) - [A Trial of SHR-7787 Injection Combined With Other Anti-tumor Drugs in Patients With Malignant Solid Tumors](https://trialight.com/data/trial/a-trial-of-shr-7787-injection-combined-with-other-anti-tumor-da2f3d8b-b801-4a58-affa-201a9708aba1.md) - An Explorative Study of HRS-2189 Combined With Adebrelimab and BP102 for Metastatic Colorectal Cancer - FUSCC Refractory TNBC Platform Study (FUTURE2.0) - SHR-1210 in Combination With BP102 and XELOX in Patient With Metastatic Colorectal Cancer - SHR-1701 Combined with SHR2554 and BP102 for MCRC - SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer - Study of SHR-1701 Plus BP102 in Subjects With Selected Solid Tumors - To Compare the Efficacy and Safety of BP102 vs. Avastin® in Combination With Paclitaxel/Carboplatin in First-line Treatment of Advanced or Relapsed NSCLC - Trial of SHR-1701 Plus BP102 in Subjects With Selected Solid Tumors ### In development for (4) - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md) Phase 2 - [Lung cancer](https://trialight.com/data/condition/lung-cancer-c4ca1fe0-9b3d-5957-a668-2d6cf26bd16a.md) Phase 2 - [Non-small cell lung carcinoma](https://trialight.com/data/condition/non-small-cell-lung-carcinoma-a86c1d60-523f-5ea7-a5e1-39ed4a2296f8.md) Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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