> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/dutogliptin-tartrate-4b9692a2-6d59-4a97-a58b-99f8a3886d31 > Record changed: 2026-10-13 # Dutogliptin tartrate Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) **Drug name** Dutogliptin tartrate Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) **Molecular weight** 391.19 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) **Structure (SMILES)** O=C(CN\[C@@H\]1CCNC1)N1CCC\[C@H\]1B(O)O.O=C(O)C(O)C(O)C(=O)O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) ### Other names (11) - boronic acid 2r 1 3r 3 pyrrolidinylamino acetyl 2 pyrrolidinyl 2r 3r 2 3 dihydroxybutanedioate 1 1 - BORONIC ACID, ((2R)-1-(((3R)-3-PYRROLIDINYLAMINO)ACETYL)-2-PYRROLIDINYL)-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1) - dutogliptin tartrate - Dutogliptin tartrate - DUTOGLIPTIN TARTRATE \[USAN\] - dutogliptin tartrate usan - phx 1149 - PHX-1149 - phx1149t - Phx1149t - PHX1149T ## Identifiers **CAS registry numbers** - 890402-81-0 **ChEMBL ID** CHEMBL4297203 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) **InChIKey** SVWHNLVZPGXBNS-RJUBDTSPSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297203) **FDA ingredient codes (UNII)** - 79QH89EV9M ### PubChem compound IDs (2) - 15949100 - 44198096 ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-gliptin ### Open Targets mechanisms - **Mechanism** Dipeptidyl peptidase IV inhibitor **Action type** Inhibitor **Target** Dipeptidyl peptidase 4 ### Investigated indications - **Condition** Diabetes Mellitus, Type 2 **Highest recorded phase** 3 **Condition identifier** MONDO:0005148 **Subject identifier** D003924 ### Open Targets indications - **Condition identifier** MONDO\_0005148 **Highest recorded phase** 3 ### Trial references (2) - NCT00482950 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00482950) - NCT00690638 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00690638) ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Heavy atoms** 27 **Molecular formula** C14H26BN3O9 **Monoisotopic mass** 391.1762096 **Natural product** No ## Related records ### Trials (12) - A Study to Evaluate Safety and Efficacy of PHX1149T in Subjects With Type 2 Diabetes Mellitus - [Dutogliptin in Co-administration With Filgrastim in Early Recovery Post-myocardial Infarction](https://trialight.com/data/trial/dutogliptin-in-co-administration-with-filgrastim-in-early-358ffdb2-79f8-4527-96ed-15ebf43cd4ab.md) - Long-term Extension Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus - Long-term Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus - Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Glimepiride With or Without Metformin - Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Pioglitazone - Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone - Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin - Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin - Safety and Efficacy Study of Dutogliptin/PHX1149T to Treat Type 2 Diabetes Mellitus - Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction - Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment ### In development for (1) - [Type 2 diabetes mellitus](https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9.md) Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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