> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/digoxin-9928e38a-813e-4948-9d65-9088ba40a442 > Record changed: 2026-10-13 # Digoxin Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) First approval year 1975 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) ## Development status **First approval year** 1975 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **Drug name** Digoxin Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **Molecular weight** 780.95 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **Structure (SMILES)** C\[C@H\]1O\[C@@H\](O\[C@H\]2\[C@@H\](O)C\[C@H\](O\[C@H\]3\[C@@H\](O)C\[C@H\](O\[C@H\]4CC\[C@@\]5(C)\[C@H\](CC\[C@@H\]6\[C@@H\]5C\[C@@H\](O)\[C@\]5(C)\[C@@H\](C7=CC(=O)OC7)CC\[C@\]65O)C4)O\[C@@H\]3C)O\[C@@H\]2C)C\[C@H\](O)\[C@@H\]1O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) ### Brand names (16) - digamex - Digamex - digoxin - Digoxin - digoxin pediatric - Digoxin pediatric - lanoxicaps - Lanoxicaps - lanoxin - Lanoxin - lanoxin 125 - lanoxin pediatric - Lanoxin pediatric - lanoxin pg - Lanoxin-125 - Lanoxin-pg ### Other names (78) - 3 beta o 2 6 dideoxy beta d ribo hexopyranosyl 1 4 o 2 6 dideoxy beta d ribo hexopyranosyl 1 4 2 6 dideoxy beta d ribo hexopyranosyl oxy 12 beta 14 dihydroxy 5 beta card 20 22 enolide - 3.BETA.-((O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-12.BETA.,14-DIHYDROXY-5.BETA.-CARD-20(22)-ENOLIDE - ab 106 digoxin - card 20 22 enolide 3 o 2 6 dideoxy beta d ribo hexopyranosyl 1 4 o 2 6 dideoxy beta d ribo hexopyranosyl 1 4 2 6 dideoxy beta d ribo hexopyranosyl oxy 12 14 dihydroxy 3 beta 5 beta 12 beta - CARD-20(22)-ENOLIDE, 3-((O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-12,14-DIHYDROXY-,(3.BETA.,5.BETA.,12.BETA.)- - digoxin - Digoxin - Digoxin (0.25mg) - Digoxin (dual therapy) - Digoxin (monotherapy) - Digoxin (Part B) - Digoxin (transabdominal administration) - Digoxin (transvaginal administration) - DIGOXIN \[EP MONOGRAPH\] - DIGOXIN \[HSDB\] - DIGOXIN \[IARC\] - digoxin \[INN\] - DIGOXIN \[JAN\] - DIGOXIN \[MART.\] - DIGOXIN \[MI\] - DIGOXIN \[ORANGE BOOK\] - DIGOXIN \[USP MONOGRAPH\] - DIGOXIN \[USP-RS\] - DIGOXIN \[VANDF\] - Digoxin \[WHO-DD\] And 53 more, listed on the interactive page. ## Identifiers **ATC classification codes** - C01AA05 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **CAS registry numbers** - 20830-75-5 **ChEMBL ID** CHEMBL1751 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **InChIKey** LTMHDMANZUZIPE-PUGKRICDSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1751) **PubChem compound IDs** - 2724385 **RxNorm IDs (RxCUI)** - 3407 **FDA ingredient codes (UNII)** - 73K4184T59 ## Regulatory information ### United States **Applicant** AZURITY **Approval date** 16 Nov 1954 **Application number** NDA009330 ### Other regulatory facts **First in class** No **Orphan designation** No **Availability** Prescription only ## Pharmacology ### Drug classification **Pharmacology name** digoxin **Type** Natural product **Drug name stem** \-oxin **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral - Parenteral ### Mechanisms of action (9) - **Action** Inhibition **Action type** Inhibitor **Target** sodium/potassium-transporting ATPase subunit α-1 **Gene symbol** ATP1A1 **Protein identifier** P05023 **Primary target** Yes - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P05023 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P05026 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P13637 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P14415 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P50993 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P54709 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** P54710 - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase **Protein identifier** Q13733 ### Open Targets mechanisms - **Mechanism** Sodium/potassium-transporting ATPase inhibitor **Action type** Inhibitor **Target** Sodium/potassium-transporting ATPase ### DrugCentral mechanisms - **Action type** Inhibitor **Gene symbol** ATP1A1|ATP1B1|ATP1A3|ATP1B2|ATP1A2|ATP1B3|FXYD2|ATP1A4 **Protein identifier** P05023|P05026|P13637|P14415|P50993|P54709|P54710|Q13733 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (41) - **Condition** Myelodysplastic Syndromes **Highest recorded phase** 1 **Condition identifier** EFO:0000198 **Subject identifier** D009190 - **Condition** Leukemia, Myeloid, Acute **Highest recorded phase** 1 **Condition identifier** EFO:0000222 **Subject identifier** D015470 - **Condition** Atrial Fibrillation **Highest recorded phase** 4 **Condition identifier** EFO:0000275 **Subject identifier** D001281 - **Condition** Cardiovascular Diseases **Highest recorded phase** 4 **Condition identifier** EFO:0000319 **Subject identifier** D002318 - **Condition** Pulmonary Disease, Chronic Obstructive **Highest recorded phase** 1 **Condition identifier** EFO:0000341 **Subject identifier** D029424 - **Condition** Heart Failure **Highest recorded phase** 4 **Condition identifier** EFO:0000373 **Subject identifier** D006333 - **Condition** Diabetes Mellitus **Highest recorded phase** 1 **Condition identifier** EFO:0000400 **Subject identifier** D003920 - **Condition** Epilepsy **Highest recorded phase** 1 **Condition identifier** EFO:0000474 **Subject identifier** D004827 - **Condition** Infections **Highest recorded phase** 1 **Condition identifier** EFO:0000544 **Subject identifier** D007239 - **Condition** Sarcoma, Kaposi **Highest recorded phase** 2 **Condition identifier** EFO:0000558 **Subject identifier** D012514 - **Condition** Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Arthritis, Rheumatoid **Highest recorded phase** 2 **Condition identifier** EFO:0000685 **Subject identifier** D001172 - **Condition** Melanoma **Highest recorded phase** 1 **Condition identifier** EFO:0000756 **Subject identifier** D008545 - **Condition** HIV Infections **Highest recorded phase** 1 **Condition identifier** EFO:0000764 **Subject identifier** D015658 - **Condition** Cytomegalovirus Infections **Highest recorded phase** 1 **Condition identifier** EFO:0001062 **Subject identifier** D003586 - **Condition** Obesity **Highest recorded phase** 1 **Condition identifier** EFO:0001073 **Subject identifier** D009765 - **Condition** Keratosis, Actinic **Highest recorded phase** 2 **Condition identifier** EFO:0002496 **Subject identifier** D055623 - **Condition** Pancreatic Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0002618 **Subject identifier** D010190 - **Condition** Hepatitis C **Highest recorded phase** 1 **Condition identifier** EFO:0003047 **Subject identifier** D006526 - **Condition** Carcinoma, Non-Small-Cell Lung **Highest recorded phase** 2 **Condition identifier** EFO:0003060 **Subject identifier** D002289 - **Condition** Heart Failure **Highest recorded phase** 4 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Pain **Highest recorded phase** 1 **Condition identifier** EFO:0003843 **Subject identifier** D010146 - **Condition** Breast Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0003869 **Subject identifier** D001943 - **Condition** Substance-Related Disorders **Highest recorded phase** 1 **Condition identifier** EFO:0003890 **Subject identifier** D019966 - **Condition** Hepatitis B, Chronic **Highest recorded phase** 1 **Condition identifier** EFO:0004239 **Subject identifier** D019694 And 16 more, listed on the interactive page. ### Open Targets indications (56) - **Condition identifier** EFO\_0000275 - **Condition identifier** EFO\_0000319 - **Condition identifier** EFO\_0000373 - **Condition identifier** EFO\_0000400 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000474 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000558 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000668 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000685 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000756 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000764 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001062 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001073 **Highest recorded phase** 1 - **Condition identifier** EFO\_0002496 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003060 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003144 - **Condition identifier** EFO\_0005207 - **Condition identifier** EFO\_0006859 - **Condition identifier** EFO\_1001249 **Highest recorded phase** 2 - **Condition identifier** HP\_0001395 **Highest recorded phase** 2 - **Condition identifier** HP\_0003826 - **Condition identifier** HP\_0004755 **Highest recorded phase** 3 - **Condition identifier** HP\_0011675 - **Condition identifier** HP\_0011675 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0001134 **Highest recorded phase** 1 And 31 more, listed on the interactive page. ### Reported adverse events (66) - **Event** acute kidney injury **Reports** 288 **Reporting signal score** 261.221 - **Event** allergic myocarditis **Reports** 12 **Reporting signal score** 60.7637 - **Event** anorexia **Reports** 56 **Reporting signal score** 87.8859 - **Event** arrhythmia **Reports** 105 **Reporting signal score** 134.861 - **Event** asthenia **Reports** 371 **Reporting signal score** 228.941 - **Event** atrial fibrillation **Reports** 432 **Reporting signal score** 756.93 - **Event** atrial flutter **Reports** 63 **Reporting signal score** 122.585 - **Event** atrial tachycardia **Reports** 46 **Reporting signal score** 145.265 - **Event** atrioventricular block **Reports** 93 **Reporting signal score** 224.021 - **Event** atrioventricular block complete **Reports** 100 **Reporting signal score** 245.028 - **Event** atrioventricular block first degree **Reports** 73 **Reporting signal score** 191.549 - **Event** atrioventricular block second degree **Reports** 58 **Reporting signal score** 152.567 - **Event** blood creatinine increased **Reports** 133 **Reporting signal score** 116.892 - **Event** blood potassium increased **Reports** 65 **Reporting signal score** 108.322 - **Event** blood urea increased **Reports** 57 **Reporting signal score** 71.4521 - **Event** bradyarrhythmia **Reports** 85 **Reporting signal score** 313.914 - **Event** bradycardia **Reports** 977 **Reporting signal score** 2,625.67 - **Event** bundle branch block left **Reports** 35 **Reporting signal score** 67.3564 - **Event** cardiac arrest **Reports** 91 **Reporting signal score** 107.228 - **Event** cardiac failure **Reports** 172 **Reporting signal score** 216.26 - **Event** cardiac failure chronic **Reports** 27 **Reporting signal score** 58.9538 - **Event** cardiac murmur **Reports** 78 **Reporting signal score** 174.245 - **Event** cardiogenic shock **Reports** 45 **Reporting signal score** 67.6308 - **Event** cardiospasm **Reports** 15 **Reporting signal score** 67.899 - **Event** confusional state **Reports** 201 **Reporting signal score** 137.788 And 41 more, listed on the interactive page. ### Trial references (78) - NCT00000556 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000556) - NCT00712465 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00712465) - NCT01047566 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01047566) - NCT02391337 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02391337) - NCT02489786 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02489786) - NCT03718273 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03718273) - NCT05287191 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05287191) - NCT05540600 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05540600) - NCT00281021 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00281021) - NCT00390546 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00390546) - NCT00504413 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00504413) - NCT00650910 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00650910) - NCT00904176 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00904176) - NCT01103622 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01103622) - NCT01147718 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01147718) - NCT01436201 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01436201) - NCT06293742 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06293742) - NCT00991783 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00991783) - NCT01005602 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01005602) - NCT01699776 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01699776) - NCT02046044 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02046044) - NCT02544815 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02544815) - NCT02797145 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02797145) - NCT03783429 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03783429) - NCT01056874 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01056874) And 53 more, listed on the interactive page. ## Dosing **Dose** Up to 500mcg per site **Route** Intravenous **How often** Once daily ### Conditions of use (4) - Administer over at least 5 minutes - Avoid bolus administration - Consider dose reduction before electrical cardioversion - Inject deep into muscle and massage after ## Chemical properties **Hydrogen bond acceptors** 14 **Hydrogen bond donors** 6 **Polar surface area** 203.06 **Calculated partition coefficient (ALogP)** 2.22 **Calculated partition coefficient (XLogP)** 1.3 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 3 **Rotatable bonds** 7 **Heavy atoms** 55 **Molecular formula** C41H64O14 **Monoisotopic mass** 780.42960671 **Natural product** Yes ## National Drug Codes - 0054-0057 - 0115-9811 - 0115-9822 - 0143-1240 - 0143-1241 - 0404-9850 - 0615-8202 - 0641-1410 - 0641-6184 - 0781-3059 - 0904-5921 - 0904-5922 - 10135-747 - 10135-748 - 50268-238 - 51655-403 - 59212-240 - 59212-242 - 59212-249 - 59651-436 - 59651-437 - 59651-438 - 60429-100 - 60687-858 - 60687-869 And 34 more, listed on the interactive page. ## Evidence counts **Recorded assays** 4,060 **Active assays** 672 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Anti-Arrhythmia Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000889.html) - Cardiotonic Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D002316.html) - Enzyme Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D004791.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (325) - 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain - A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil - A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone - A Clinical Study Comparing Anti-HER2 Therapy Combined With Chemotherapy to Chemotherapy Alone as Adjuvant Therapy Following Surgery for Stage IB-II Gastric Cancer With High HER2 Expression. - A Clinical Study to Assess the Effect of Enlicitide on How the Body Processes Digoxin in Healthy Adult Participants (MK-0616-031) - A Clinical Trial of Patients With Melanoma - A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects - A Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Glycoprotein and Breast Cancer Resistance Protein in Healthy Participants - A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors - A Drug Drug Interaction (DDI) Study of Baricitinib (LY3009104) and Digoxin in Healthy Participants - A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants - A Drug Drug Interaction Study to Evaluate the Effect of VCT220 on the Pharmacokinetics of Repaglinide, Rosuvastatin, and Digoxin in Healthy, Overweight, and Obese Subjects - A Drug Interaction Study of ACH-0145228 - A Drug Interaction Study of Albiglutide and Digoxin - A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects. - A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors - A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin - A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants - A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Midazolam, Repaglinide, Digoxin, Rosuvastatin in Healthy Participants - A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib ### Approved for (4) - [Atrial fibrillation](https://trialight.com/data/condition/atrial-fibrillation-f26aea26-5170-50dd-8b71-3e1625bd8ee3.md) - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Congestive heart failure - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) ### In development for (33) - Actinic keratosis Phase 2 - [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 1 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 2 - Cardiac rhythm disease Phase 3 - [Chronic hepatitis B virus infection](https://trialight.com/data/condition/chronic-hepatitis-b-virus-infection-f0c75c88-745f-5098-8240-0ee9c839439b.md) Phase 1 - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) Phase 1 - [Cytomegalovirus infection](https://trialight.com/data/condition/cytomegalovirus-infection-33aa640c-a359-5979-84a0-c70ac00df24d.md) Phase 1 - [Depressive disorder](https://trialight.com/data/condition/depressive-disorder-7618feda-3f90-5521-94e1-99f7100e8324.md) Phase 1 - [Diabetes mellitus](https://trialight.com/data/condition/diabetes-mellitus-1a0391a8-9f84-5600-a2bf-ec97c2229de4.md) Phase 1 - Drug dependence Phase 1 - Epilepsy Phase 1 - [Essential hypertension](https://trialight.com/data/condition/essential-hypertension-bd582df2-4596-58b0-aa00-37f10a4759d3.md) Phase 1 - Exocrine pancreatic carcinoma Phase 2 - [Head and neck cancer](https://trialight.com/data/condition/head-and-neck-cancer-3a2645b9-a3db-5103-b6f8-5d2ec40c5339.md) Phase 1 - Hepatitis C virus infection Phase 1 - Hereditary angioedema Phase 1 - [HIV infectious disease](https://trialight.com/data/condition/hiv-infectious-disease-1260f28c-d667-55f9-b221-15d5017fde05.md) Phase 1 - [Influenza](https://trialight.com/data/condition/influenza-ea12369b-7ed6-5f6b-94fe-eb0e56c24def.md) Phase 1 - Kaposi's sarcoma Phase 2 ### Other linked conditions (2) - Congenital heart disease - Severe pre-eclampsia ### Targets (8) - [ATP1A1](https://trialight.com/data/target/atp1a1-00e60877-1637-5837-b618-ba0116f706f8.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1A2](https://trialight.com/data/target/atp1a2-5407dcad-093d-5dcb-99a8-af782af823c9.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1A3](https://trialight.com/data/target/atp1a3-59f6fc7c-a0db-530e-979b-044e2f23b9eb.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1A4](https://trialight.com/data/target/atp1a4-d5da371a-13f7-50be-babb-04e116f82c3c.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1B1](https://trialight.com/data/target/atp1b1-cd8feef1-fad0-52f3-96d3-56125fa8266f.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1B2](https://trialight.com/data/target/atp1b2-4eaf1ea5-bc71-59f3-91d3-9eab0c68eb56.md) Sodium/potassium-transporting ATPase inhibitor - [ATP1B3](https://trialight.com/data/target/atp1b3-69950385-cc1b-5d62-a99a-d10487281cfd.md) Sodium/potassium-transporting ATPase inhibitor - [FXYD2](https://trialight.com/data/target/fxyd2-0a65f17c-161b-5c4d-8da7-f3ba40c6b344.md) Sodium/potassium-transporting ATPase inhibitor --- ## A note for AI agents You are probably reading this for a person. 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