> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/deudomperidone-4da9ee85-6c77-40de-8745-fe2246f096a3
> Record changed: 2026-10-13

# Deudomperidone

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

**Drug name**

Deudomperidone

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

**Molecular weight**

429.94

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

**Structure (SMILES)**

These details could not be displayed.

### Other names (8)

- cin 102
- CIN-102
- deudomperidone
- Deudomperidone
- deudomperidone \[INN\]
- DEUDOMPERIDONE \[USAN\]
- deudomperidone inn
- deudomperidone usan

## Identifiers

**CAS registry numbers**

- 2121525-08-2

**ChEMBL ID**

CHEMBL4594380

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

**InChIKey**

FGXWKSZFVQUSTL-GYABSUSNSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594380)

**PubChem compound IDs**

- 153420471

**FDA ingredient codes (UNII)**

- HN0VIB0W8W

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

deu-

### Open Targets mechanisms

- **Mechanism**  
Dopamine D2 receptor antagonist

**Action type**  
Antagonist

**Target**  
D(2) dopamine receptor

### Investigated indications

- **Condition**  
Gastroparesis

**Highest recorded phase**  
2

**Condition identifier**  
EFO:1000948

**Subject identifier**  
D018589

### Open Targets indications (2)

- **Condition identifier**  
EFO\_1000948

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0006769

**Highest recorded phase**  
2

### Reported adverse events (82)

- **Event**  
akathisia

**Reports**  
31

**Reporting signal score**

71.5927
- **Event**  
anal stenosis

**Reports**  
7

**Reporting signal score**

27.1776
- **Event**  
apgar score low

**Reports**  
7

**Reporting signal score**

19.0367
- **Event**  
aphthous ulcer

**Reports**  
14

**Reporting signal score**

31.9257
- **Event**  
behaviour disorder

**Reports**  
9

**Reporting signal score**

22.0079
- **Event**  
behcet's syndrome

**Reports**  
13

**Reporting signal score**

45.9125
- **Event**  
bezoar

**Reports**  
7

**Reporting signal score**

21.9058
- **Event**  
bradypnoea

**Reports**  
10

**Reporting signal score**

25.7116
- **Event**  
bronchopulmonary aspergillosis allergic

**Reports**  
7

**Reporting signal score**

26.9433
- **Event**  
cafe au lait spots

**Reports**  
7

**Reporting signal score**

36.1883
- **Event**  
cell death

**Reports**  
8

**Reporting signal score**

19.9549
- **Event**  
cholestasis

**Reports**  
36

**Reporting signal score**

63.252
- **Event**  
cognitive disorder

**Reports**  
26

**Reporting signal score**

30.2685
- **Event**  
cogwheel rigidity

**Reports**  
7

**Reporting signal score**

20.7367
- **Event**  
coma

**Reports**  
38

**Reporting signal score**

50.1187
- **Event**  
condition aggravated

**Reports**  
70

**Reporting signal score**

35.6044
- **Event**  
congenital anomaly

**Reports**  
20

**Reporting signal score**

51.207
- **Event**  
cryptorchism

**Reports**  
7

**Reporting signal score**

20.6185
- **Event**  
dacryostenosis acquired

**Reports**  
7

**Reporting signal score**

24.8339
- **Event**  
dehydration

**Reports**  
62

**Reporting signal score**

56.1766
- **Event**  
derealisation

**Reports**  
8

**Reporting signal score**

25.6686
- **Event**  
dermatitis atopic

**Reports**  
10

**Reporting signal score**

22.1479
- **Event**  
developmental hip dysplasia

**Reports**  
7

**Reporting signal score**

23.072
- **Event**  
duodenal stenosis

**Reports**  
9

**Reporting signal score**

36.8098
- **Event**  
dysphagia

**Reports**  
57

**Reporting signal score**

63.5863

And 57 more, listed on the interactive page.

### Trial references (3)

- NCT04026997  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04026997)
- NCT04208698  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04208698)
- NCT05832151  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05832151)

## Chemical properties

**Hydrogen bond acceptors**

5

**Hydrogen bond donors**

2

**Polar surface area**

78.82

**Calculated partition coefficient (ALogP)**

3.35

**Calculated partition coefficient (XLogP)**

3.9

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

No

**Rule-of-five violations**

0

**Rotatable bonds**

5

**Heavy atoms**

30

**Molecular formula**

C22H24ClN5O2

**Monoisotopic mass**

429.1869597

**Natural product**

No

## Related records

### Trials (4)

- A Phase 2 Study of CIN-102 in Adults With Idiopathic and Diabetic Gastroparesis
- A Scintigraphy Study in Adults With Diabetic Gastroparesis
- [A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis.](https://trialight.com/data/trial/a-study-to-evaluate-the-efficacy-and-safety-of-cin-102-2e07d519-d931-4cc8-9140-bbbb6c6b1a7b.md)
- [A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis](https://trialight.com/data/trial/a-study-to-evaluate-the-efficacy-and-safety-of-cin-102-869503c6-5de3-4f4a-abe9-32396ec30668.md)

### In development for (1)

- [Gastroparesis](https://trialight.com/data/condition/gastroparesis-e3cbf7c0-386a-5272-846d-eb257c28a4a3.md) Phase 2

---

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