> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/deloxolone-eed99820-cda6-4732-b5a3-3b2dd34bf79e
> Record changed: 2026-10-13

# Deloxolone

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

**Drug name**

Deloxolone

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

**Molecular weight**

556.78

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

**Structure (SMILES)**

CC1(C)\[C@@H\](OC(=O)CCC(=O)O)CC\[C@\]2(C)C3=CC\[C@@H\]4\[C@@H\]5C\[C@@\](C)(C(=O)O)CC\[C@\]5(C)CC\[C@@\]4(C)\[C@\]3(C)CC\[C@@H\]12

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

### Other names (8)

- 3 beta hydroxyolean 9 11 en 30 oic acid hydrogen succinate
- 3.BETA.-HYDROXYOLEAN-9(11)-EN-30-OIC ACID, HYDROGEN SUCCINATE
- deloxolona
- Deloxolona
- deloxolone
- Deloxolone
- deloxolone \[INN\]
- deloxolone inn

## Identifiers

**CAS registry numbers**

- 68635-50-7

**ChEMBL ID**

CHEMBL2106405

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

**InChIKey**

VRFVGZRKFFTPCG-KYHPDETOSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106405)

**PubChem compound IDs**

- 205973

**FDA ingredient codes (UNII)**

- I0E16819I3

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-olone

## Chemical properties

**Hydrogen bond acceptors**

4

**Hydrogen bond donors**

2

**Polar surface area**

100.9

**Calculated partition coefficient (ALogP)**

7.65

**Calculated partition coefficient (XLogP)**

7.6

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Rule-of-five violations**

2

**Rotatable bonds**

5

**Heavy atoms**

40

**Molecular formula**

C34H52O6

**Monoisotopic mass**

556.37638937

**Natural product**

No

## Related records

### Trials (49)

- A Phase I Trial Evaluate the Safety and Tolerability Profile of HPV Vaccine
- A Phase II Trial Evaluate the Immunogenicity and Safety Profile of HPV Vaccine
- [A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males](https://trialight.com/data/trial/a-phase-iii-study-to-evaluate-the-efficacy-immunogenicity-219c05bd-7219-460e-afb4-31c216079542.md)
- [A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females](https://trialight.com/data/trial/a-phase-iii-study-to-evaluate-the-efficacy-immunogenicity-5428ea99-be6b-4e66-9faa-9ad750a3bf50.md)
- A Phase III Trial Evaluates the Efficacy, Immunogenicity and Safety Profile of HPV Vaccine
- A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
- [A Study to Evaluate the Immunogenicity and Safety of HPV Vaccine in Healthy Female Participants Aged 9-26 Years in China](https://trialight.com/data/trial/a-study-to-evaluate-the-immunogenicity-and-safety-of-hpv-c83859dc-0c17-4639-bb21-b1aa42234b97.md)
- A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)
- A Study to Evaluate Tolerability and Immunogenicity of V504 Administered Concomitantly With GARDASIL (V504-001)(COMPLETED)
- An Immunogenicity and Safety Study of Gardasil® in Chinese Subjects (V501-030)(COMPLETED)
- An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)
- An Open-Label, Single Dose Safety Study of Quadrivalent HPV Vaccine in Chinese Female Subjects (V501-035)
- Antibody Response to Prophylactic QHPV Vaccine at 48 Months Among HIV-infected Girls and Boys
- Broad Spectrum HPV (Human Papillomavirus) Vaccine in 16 to 26 Year Old Women (V505-001)
- Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil) (V501-015)
- Concomitant Use of Gardasil (V501, Human Papillomavirus \[Types 6, 11, 16, 18\] Recombinant Vaccine) With Combined Diptheria, Tetanus, Pertussis and Poliomyelitis Vaccine in Adolescents (V501-024)(COMPLETED)
- Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?
- Effectiveness and B-memory Cell Response to QHPV Vaccine 9-years Post-vaccination Among HIV-infected Boys and Girls
- Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
- Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

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