> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356 > Record changed: 2026-10-13 # Dapagliflozin Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) First approval year 2012 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) ## Development status **First approval year** 2012 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **Drug name** Dapagliflozin Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **Molecular weight** 408.88 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **Structure (SMILES)** CCOc1ccc(Cc2cc(\[C@@H\]3O\[C@H\](CO)\[C@@H\](O)\[C@H\](O)\[C@H\]3O)ccc2Cl)cc1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) ### Brand names (12) - dapagliflozin component of br1019 - Dapagliflozin component of br1019 - dapagliflozin component of qtern - Dapagliflozin component of qtern - dapagliflozin component of qternmet - Dapagliflozin component of qternmet - Dapagliflozin component of qternmet dapaglifozin - dapagliflozin component of qternmet dapaglifozin - dapagliflozin component of qternmet xr - Dapagliflozin component of qternmet xr - dapagliflozin viatris - Dapagliflozin viatris ### Other names (52) - balcinrenone dapagliflozin - bms 512148 - BMS-512148 - br1019 component dapagliflozin - BR1019 component Dapagliflozin - dapagliflozin - Dapagliflozin - Dapagliflozin (DAPA) - Dapagliflozin (Treatment A) - dapagliflozin \[INN\] - DAPAGLIFLOZIN \[MI\] - DAPAGLIFLOZIN \[ORANGE BOOK\] - DAPAGLIFLOZIN \[USAN\] - DAPAGLIFLOZIN \[VANDF\] - Dapagliflozin \[WHO-DD\] - Dapagliflozin 10 mg - Dapagliflozin 10 MG - Dapagliflozin 10 mg daily - Dapagliflozin 10 mg film-coated tablet - Dapagliflozin 10 MG Oral Tablet - Dapagliflozin 10 mg tablets - Dapagliflozin 10mg - Dapagliflozin 10Mg Oral Tablet - Dapagliflozin 10mg QD - Dapagliflozin 5 mg And 27 more, listed on the interactive page. ## Identifiers **ATC classification codes** - A10BK01 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **CAS registry numbers** - 461432-26-8 **ChEMBL ID** CHEMBL429910 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **InChIKey** JVHXJTBJCFBINQ-ADAARDCZSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL429910) **PubChem compound IDs** - 9887712 **RxNorm IDs (RxCUI)** - 1488564 **FDA ingredient codes (UNII)** - 1ULL0QJ8UC ## Regulatory information ### United States **Applicant** ASTRAZENECA AB **Approval date** 8 Jan 2014 **Application number** NDA202293 ### European Union **Status** Authorised **Status date** 11 Nov 2012 **Authorisation date** 11 Nov 2012 **Approved indications** Type 2 diabetes mellitus Forxiga is indicated in adults and children aged 10 years and above for the treatment of insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance. in addition to other medicinal products for the treatment of type 2 diabetes. For study results with respect to combination of therapies, effects on glycaemic control, cardiovascular and renal events, and the populations studied, see sections 4.4, 4.5 and 5.1\. Heart failure Forxiga is indicated in adults for the treatment of symptomatic chronic heart failure. Chronic kidney disease Forxiga is indicated in adults for the treatment of chronic kidney disease. **Product number** EMEA/H/C/002322 **Authorisation holder** AstraZeneca AB **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 1 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Diabetes Mellitus, Type 2 - Heart Failure - Heart Failure, Systolic - Renal Insufficiency, Chronic European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/forxiga) ### Other regulatory facts **Patents** 34 **Designations** 2 **Earliest recorded loss of exclusivity** 1 Oct 2041 **First in class** No **Fast track** No **Breakthrough designation** Yes **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification **Pharmacology name** dapagliflozin **Type** Synthetic organic **Drug name stem** \-gliflozin **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (4) - **Action** Activation **Action type** ACTIVATION **Target** K2P7.1 **Gene symbol** KCNK7 **Protein identifier** Q9Y2U2 **Median affinity** 4 **Affinity units** pEC50 - **Action** Inhibition **Action type** Inhibitor **Target** Sodium/glucose cotransporter 1 **Gene symbol** SLC5A1 **Protein identifier** P13866 **Median affinity** 6.4 **Affinity units** pIC50 - **Action** Inhibition **Action type** Inhibitor **Target** Sodium/glucose cotransporter 2 **Gene symbol** SLC5A2 **Protein identifier** P31639 **Median affinity** 9.3 **Affinity units** pIC50 **Primary target** Yes - **Mechanism** Sodium/glucose cotransporter 2 inhibitor **Action type** Inhibitor **Target** Sodium/glucose cotransporter 2 **Protein identifier** P31639 ### Open Targets mechanisms - **Mechanism** Sodium/glucose cotransporter 2 inhibitor **Action type** Inhibitor **Target** Sodium/glucose cotransporter 2 ### DrugCentral mechanisms - **Action type** Inhibitor **Gene symbol** SLC5A2 **Protein identifier** P31639 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (45) - **Condition** Metabolic Syndrome **Highest recorded phase** 2 **Condition identifier** EFO:0000195 **Subject identifier** D024821 - **Condition** Atrial Fibrillation **Highest recorded phase** 3 **Condition identifier** EFO:0000275 **Subject identifier** D001281 - **Condition** Diabetes Mellitus **Highest recorded phase** 4 **Condition identifier** EFO:0000400 **Subject identifier** D003920 - **Condition** Diabetic Nephropathies **Highest recorded phase** 2 **Condition identifier** EFO:0000401 **Subject identifier** D003928 - **Condition** Myocardial Infarction **Highest recorded phase** 2 **Condition identifier** EFO:0000612 **Subject identifier** D009203 - **Condition** Polycystic Ovary Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000660 **Subject identifier** D011085 - **Condition** Obesity **Highest recorded phase** 2 **Condition identifier** EFO:0001073 **Subject identifier** D009765 - **Condition** Hypertension, Pulmonary **Highest recorded phase** 2 **Condition identifier** EFO:0001361 **Subject identifier** D006976 - **Condition** Liver Cirrhosis **Highest recorded phase** 2 **Condition identifier** EFO:0001422 **Subject identifier** D008103 - **Condition** Coronary Disease **Highest recorded phase** 3 **Condition identifier** EFO:0001645 **Subject identifier** D003327 - **Condition** Prostatic Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0001663 **Subject identifier** D011471 - **Condition** Insulin Resistance **Highest recorded phase** 3 **Condition identifier** EFO:0002614 **Subject identifier** D007333 - **Condition** Pancreatic Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0002618 **Subject identifier** D010190 - **Condition** Reperfusion Injury **Highest recorded phase** 1 **Condition identifier** EFO:0002687 **Subject identifier** D015427 - **Condition** Heart Failure **Highest recorded phase** 4 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Inflammatory Bowel Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0003767 **Subject identifier** D015212 - **Condition** Diabetic Retinopathy **Highest recorded phase** 3 **Condition identifier** EFO:0003770 **Subject identifier** D003930 - **Condition** Brain Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0003833 **Subject identifier** D001932 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 4 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Motor Activity **Highest recorded phase** 2 **Condition identifier** EFO:0003940 **Subject identifier** D009043 - **Condition** Glomerulonephritis, IGA **Highest recorded phase** 3 **Condition identifier** EFO:0004194 **Subject identifier** D005922 - **Condition** Albuminuria **Highest recorded phase** 2 **Condition identifier** EFO:0004285 **Subject identifier** D000419 - **Condition** Lupus Nephritis **Highest recorded phase** 1 **Condition identifier** EFO:0005761 **Subject identifier** D008181 - **Condition** ST Elevation Myocardial Infarction **Highest recorded phase** 3 **Condition identifier** EFO:0008585 **Subject identifier** D000072657 - **Condition** Hyperuricemia **Highest recorded phase** 2 **Condition identifier** EFO:0009104 **Subject identifier** D033461 And 20 more, listed on the interactive page. ### Open Targets indications (146) - **Condition identifier** EFO\_0000195 - **Condition identifier** EFO\_0000195 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000266 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000275 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000400 - **Condition identifier** EFO\_0000401 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000537 - **Condition identifier** EFO\_0000589 - **Condition identifier** EFO\_0000612 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000660 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001361 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001422 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001645 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001663 **Highest recorded phase** 1 - **Condition identifier** EFO\_0002618 **Highest recorded phase** 1 - **Condition identifier** EFO\_0002687 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003086 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003144 - **Condition identifier** EFO\_0003770 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003884 - **Condition identifier** EFO\_0003913 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003940 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004285 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004952 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005761 **Highest recorded phase** 2 And 121 more, listed on the interactive page. ### Reported adverse events (30) - **Event** acute kidney injury **Reports** 186 **Reporting signal score** 133.717 - **Event** bladder cancer **Reports** 44 **Reporting signal score** 77.8048 - **Event** blood glucose increased **Reports** 135 **Reporting signal score** 147.609 - **Event** cardiospasm **Reports** 15 **Reporting signal score** 71.0148 - **Event** dehydration **Reports** 119 **Reporting signal score** 63.2105 - **Event** diabetes mellitus inadequate control **Reports** 71 **Reporting signal score** 138.952 - **Event** diabetic ketoacidosis **Reports** 769 **Reporting signal score** 2,759.89 - **Event** euglycaemic diabetic ketoacidosis **Reports** 183 **Reporting signal score** 718.638 - **Event** fournier's gangrene **Reports** 53 **Reporting signal score** 176.025 - **Event** fungal infection **Reports** 211 **Reporting signal score** 521.725 - **Event** glomerular filtration rate decreased **Reports** 45 **Reporting signal score** 77.16 - **Event** glucose urine present **Reports** 20 **Reporting signal score** 61.3462 - **Event** glycosylated haemoglobin increased **Reports** 98 **Reporting signal score** 216.953 - **Event** hyperglycaemia **Reports** 70 **Reporting signal score** 75.5786 - **Event** immunisation **Reports** 11 **Reporting signal score** 50.2411 - **Event** ketoacidosis **Reports** 190 **Reporting signal score** 674.912 - **Event** ketonuria **Reports** 31 **Reporting signal score** 111.833 - **Event** ketosis **Reports** 31 **Reporting signal score** 114.403 - **Event** lactic acidosis **Reports** 63 **Reporting signal score** 58.7435 - **Event** metabolic acidosis **Reports** 116 **Reporting signal score** 187.059 - **Event** necrotising fasciitis **Reports** 30 **Reporting signal score** 74.0961 - **Event** palmoplantar keratoderma **Reports** 15 **Reporting signal score** 56.0161 - **Event** pollakiuria **Reports** 50 **Reporting signal score** 56.5228 - **Event** polyuria **Reports** 32 **Reporting signal score** 51.2678 - **Event** pruritus genital **Reports** 24 **Reporting signal score** 76.2873 And 5 more, listed on the interactive page. ### Trial references (253) - NCT00162305 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00162305) - NCT00263276 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00263276) - NCT00357370 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00357370) - NCT00528372 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00528372) - NCT00528879 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00528879) - NCT00538174 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00538174) - NCT00554450 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00554450) - NCT00562250 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00562250) - NCT00643851 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00643851) - NCT00660907 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00660907) - NCT00663260 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00663260) - NCT00673231 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00673231) - NCT00680745 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00680745) - NCT00683878 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00683878) - NCT00736879 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00736879) - NCT00831779 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00831779) - NCT00839683 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00839683) - NCT00842556 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00842556) - NCT00855166 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00855166) - NCT00859898 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00859898) - NCT00904176 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00904176) - NCT00908271 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00908271) - NCT00930865 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00930865) - NCT00972244 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00972244) - NCT00976495 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00976495) And 228 more, listed on the interactive page. ## Dosing **Dose** 5 mg **Route** Oral **How often** Once daily ### Conditions of use - Take with food ## Chemical properties **Hydrogen bond acceptors** 6 **Hydrogen bond donors** 4 **Polar surface area** 99.38 **Calculated partition coefficient (ALogP)** 1.84 **Calculated partition coefficient (XLogP)** 2.3 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 6 **Heavy atoms** 28 **Molecular formula** C21H25ClO6 **Monoisotopic mass** 408.1339662 **Natural product** Yes ## National Drug Codes - 0480-3527 - 0480-3528 - 0781-5985 - 0781-5990 - 27241-151 - 27241-152 - 33342-406 - 33342-407 - 33342-408 - 33342-409 - 33342-585 - 33342-586 - 46708-392 - 46708-393 - 59651-154 - 59651-155 - 59651-156 - 59651-157 - 59651-159 - 59651-160 - 62332-392 - 62332-393 - 63304-026 - 63304-027 - 63304-028 And 36 more, listed on the interactive page. ## Evidence counts **Recorded assays** 415 **Active assays** 81 ### Active assay types (2) - Confirmatory - Other ## Pharmacologic actions - Sodium-Glucose Transporter 2 Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000077203.html) ## Biological measurements ### Observed measurements #### Oral bioavailability **Median** 88.2 **Mean** 88.6367 **Minimum** 83 **Maximum** 100 **Unit** % **Assays** 6 **Standard deviation** 6.04821 **Summary method** median **Censored results excluded** 0 **Other units excluded** 0 **Unknown units excluded** 0 #### Measurement types - F ## Related records ### Trials (577) - "Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes" - "Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial" - A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin - A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone - A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic Kidney Disease - A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting. - A Clinical Study to Investigate the Effects of Dapagliflozin on Heart Work, Heart Nutrient Uptake, and Heart Muscle Efficiency in Type 2 Diabetes Patients - A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal - A Clinical Trial to Evaluate the Blood Pressure Lowering Effect of a Candemore Plus Tab Versus Cantabell Tab in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy - A Clinical Trial to Evaluate the Bone Metabolism and the Blood Sugar of Evogliptin and Dapagliflozin - A Clinical Trial to Evaluate the Safety and the Pharmacokinetic Interaction of Telmisartan and Dapagliflozin. - A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI) - A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes - A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes - A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers - A Phase 2b Diabetic Kidney Disease Study - A Phase 3 Study to Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus - A Phase I PK Study of Balcinrenone/Dapagliflozin in Healthy Chinese Participants - A Phase Ib Study of AZD5462 on Top of Dapagliflozin in Participants With Heart Failure and Moderate Renal Impairment - A Phase IIA Study of BMS-512148 to Assess Safety, Exposure, and Biological Effects in Stable Type 2 Diabetic Subjects ### Approved for (4) - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) - [Diabetes mellitus](https://trialight.com/data/condition/diabetes-mellitus-1a0391a8-9f84-5600-a2bf-ec97c2229de4.md) - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) - [Type 2 diabetes mellitus](https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9.md) ### In development for (37) - Acute kidney injury Phase 3 - AL amyloidosis Phase 2 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 1 - [Atrial fibrillation](https://trialight.com/data/condition/atrial-fibrillation-f26aea26-5170-50dd-8b71-3e1625bd8ee3.md) Phase 3 - [Brain neoplasm](https://trialight.com/data/condition/brain-neoplasm-b3dac71b-1d7b-5a65-8f64-89821506ad41.md) Phase 1 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [Chronic renal failure syndrome](https://trialight.com/data/condition/chronic-renal-failure-syndrome-5b98a1aa-2089-59e6-af27-bff008ad07ac.md) Phase 3 - [Cirrhosis of liver](https://trialight.com/data/condition/cirrhosis-of-liver-d90e4a84-9e82-54fc-a553-1e42086e8382.md) Phase 2 - [Coronary artery disorder](https://trialight.com/data/condition/coronary-artery-disorder-6f736849-d477-587a-b3fa-b0621d573407.md) Phase 3 - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - Cystinuria Phase 2 - [Depressive disorder](https://trialight.com/data/condition/depressive-disorder-7618feda-3f90-5521-94e1-99f7100e8324.md) Phase 2 - [Diabetic kidney disease](https://trialight.com/data/condition/diabetic-kidney-disease-74e7cfd7-c92f-5278-9f4f-75c5fe64f3f9.md) Phase 2 - Diabetic neuropathy Phase 2 - [Diabetic retinopathy](https://trialight.com/data/condition/diabetic-retinopathy-3213cb12-9e5d-5ef7-827d-b64b152d71f9.md) Phase 3 - [Diastolic heart failure](https://trialight.com/data/condition/diastolic-heart-failure-b3fbecba-f0d5-5a66-ac3b-8843d29791ea.md) Phase 2 - Exocrine pancreatic carcinoma Phase 1 - Fabry disease Phase 2 - Fatty liver disease Phase 3 - [IgA glomerulonephritis](https://trialight.com/data/condition/iga-glomerulonephritis-f6f68a56-7253-54d9-9456-5d9ece4d1a52.md) Phase 3 ### Other linked conditions (5) - Alport syndrome - [Glucose metabolism disease](https://trialight.com/data/condition/glucose-metabolism-disease-e258cc9e-1eda-56cb-80f3-f4bd7a42bc71.md) - [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md) - Metabolic disease - Systolic heart failure ### Targets (1) - [SLC5A2](https://trialight.com/data/target/slc5a2-892977fc-aff4-53e6-bd99-b55f23594492.md) Sodium/glucose cotransporter 2 inhibitor --- ## A note for AI agents You are probably reading this for a person. 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