> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf > Record changed: 2026-10-13 # Colchicine Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) First approval year 1961 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) ## Development status **First approval year** 1961 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **Drug name** Colchicine Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **Molecular weight** 399.44 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **Structure (SMILES)** COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1\[C@@H\](NC(C)=O)CC2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) ### Brand names (16) - colchicine component of col probenecid - Colchicine component of col-probenecid - colchicine component of colbenemid - Colchicine component of colbenemid - colchicine component of mitigare - Colchicine component of mitigare - colchicine component of proben c - Colchicine component of proben-c - colcrys - Colcrys - gloperba - Gloperba - lodoco - Lodoco - mitigare - Mitigare ### Other names (80) - (-)-colchicine - 0 5mg oral colchicine - acetamide n 5 6 7 9 tetrahydro 1 2 3 10 tetramethoxy 9 oxobenzo a heptalen 7 yl s - ACETAMIDE, N-(5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO(A)HEPTALEN-7-YL)-,(S)- - col probenecid component colchicine - COL-PROBENECID COMPONENT COLCHICINE - colbenemid component colchicine - COLBENEMID COMPONENT COLCHICINE - colchcine - Colchcine - COLCHCINE \[VANDF\] - colchcine vandf - colchicine - Colchicine - Colchicine (Colcrys®) - Colchicine (for 1 month) - Colchicine (for 3 months) - Colchicine (for 6 months) - COLCHICINE \[EP IMPURITY\] - COLCHICINE \[EP MONOGRAPH\] - COLCHICINE \[HSDB\] - COLCHICINE \[JAN\] - COLCHICINE \[MART.\] - COLCHICINE \[MI\] - COLCHICINE \[ORANGE BOOK\] And 55 more, listed on the interactive page. ## Identifiers **ATC classification codes** - M04AC01 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **CAS registry numbers** - 64-86-8 **ChEMBL ID** CHEMBL107 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **InChIKey** IAKHMKGGTNLKSZ-INIZCTEOSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL107) **PubChem compound IDs** - 6167 **RxNorm IDs (RxCUI)** - 2683 **FDA ingredient codes (UNII)** - SML2Y3J35T ## Regulatory information ### United States **Applicant** HIKMA INTL PHARMS **Approval date** 26 Sept 2014 **Application number** NDA204820 ### European Union **Status** opinion **Status date** 21 May 2026 **Approved indications** Indicated to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in patients with atherosclerotic disease or with multiple risk factors for cardiovascular disease. **Product number** EMEA/H/C/006653 **Authorisation holder** Agepha Pharma s.r.o. **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Coronary Artery Disease - Myocardial Infarction - Stroke European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/colchicine-agepha-pharma) ### Other regulatory facts **Patents** 41 **Designations** 2 **Earliest recorded loss of exclusivity** 20 Dec 2037 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification **Pharmacology name** colchicine **Type** Synthetic organic **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (21) - **Action** Agonist **Action type** Agonist **Target** TAS2R46 **Gene symbol** TAS2R46 **Protein identifier** P59540 **Median affinity** 2.8 **Affinity units** pEC50 - **Action** Agonist **Action type** Agonist **Target** TAS2R4 **Gene symbol** TAS2R4 **Protein identifier** Q9NYW5 **Median affinity** 2.99 **Affinity units** pEC50 - **Action** Antagonist **Action type** Antagonist **Target** glycine receptor α1 subunit **Gene symbol** GLRA1 **Protein identifier** P23415 **Median affinity** 3.5 **Affinity units** pIC50 - **Action** Antagonist **Action type** Antagonist **Target** glycine receptor α2 subunit **Gene symbol** GLRA2 **Protein identifier** P23416 **Median affinity** 4.2 **Affinity units** pIC50 - **Action** Inhibition **Action type** Inhibitor **Target** bromodomain containing 4 **Gene symbol** BRD4 **Protein identifier** O60885 **Median affinity** 4.7 **Affinity units** pKd - **Action** Inhibition **Action type** Inhibitor **Target** tubulin beta class I **Gene symbol** TUBB **Protein identifier** P07437 **Median affinity** 7.96 **Affinity units** pIC50 **Primary target** Yes - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P04350 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P07437 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P0DPH7 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68363 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68366 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68371 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q13509 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q13885 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q3ZCM7 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q6PEY2 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q71U36 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BQE3 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BUF5 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BVA1 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9H4B7 ### Open Targets mechanisms - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin ### DrugCentral mechanisms (2) - **Action type** Inhibitor **Gene symbol** BRD4 **Protein identifier** O60885 **Organism** Homo sapiens **Target development level** Chemical evidence - **Action type** Inhibitor **Gene symbol** TUBB **Protein identifier** P07437 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (42) - **Condition** Atrial Fibrillation **Highest recorded phase** 3 **Condition identifier** EFO:0000275 **Subject identifier** D001281 - **Condition** Cardiovascular Diseases **Highest recorded phase** 3 **Condition identifier** EFO:0000319 **Subject identifier** D002318 - **Condition** Diabetic Nephropathies **Highest recorded phase** 2 **Condition identifier** EFO:0000401 **Subject identifier** D003928 - **Condition** Hypertension **Highest recorded phase** 2 **Condition identifier** EFO:0000537 **Subject identifier** D006973 - **Condition** Intracranial Hemorrhages **Highest recorded phase** 2 **Condition identifier** EFO:0000551 **Subject identifier** D020300 - **Condition** Myocardial Infarction **Highest recorded phase** 3 **Condition identifier** EFO:0000612 **Subject identifier** D009203 - **Condition** Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000694 **Subject identifier** D045169 - **Condition** Multiple Myeloma **Highest recorded phase** 3 **Condition identifier** EFO:0001378 **Subject identifier** D009101 - **Condition** Liver Cirrhosis **Highest recorded phase** 1 **Condition identifier** EFO:0001422 **Subject identifier** D008103 - **Condition** Coronary Disease **Highest recorded phase** 3 **Condition identifier** EFO:0001645 **Subject identifier** D003327 - **Condition** Reperfusion Injury **Highest recorded phase** 3 **Condition identifier** EFO:0002687 **Subject identifier** D015427 - **Condition** Heart Failure **Highest recorded phase** 3 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Heart Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0003777 **Subject identifier** D006331 - **Condition** Behcet Syndrome **Highest recorded phase** 2 **Condition identifier** EFO:0003780 **Subject identifier** D001528 - **Condition** Lung Diseases **Highest recorded phase** 3 **Condition identifier** EFO:0003818 **Subject identifier** D008171 - **Condition** Urogenital Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0003863 **Subject identifier** D014565 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 2 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Atherosclerosis **Highest recorded phase** 2 **Condition identifier** EFO:0003914 **Subject identifier** D050197 - **Condition** Stomatitis, Aphthous **Highest recorded phase** 2 **Condition identifier** EFO:0003938 **Subject identifier** D013281 - **Condition** Hepatitis C, Chronic **Highest recorded phase** 2 **Condition identifier** EFO:0004220 **Subject identifier** D019698 - **Condition** Vascular Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0004264 **Subject identifier** D014652 - **Condition** Peripheral Arterial Disease **Highest recorded phase** 0.5 **Condition identifier** EFO:0004265 **Subject identifier** D058729 - **Condition** Arrhythmias, Cardiac **Highest recorded phase** 3 **Condition identifier** EFO:0004269 **Subject identifier** D001145 - **Condition** Gout **Highest recorded phase** 4 **Condition identifier** EFO:0004274 **Subject identifier** D006073 And 17 more, listed on the interactive page. ### Open Targets indications (117) - **Condition identifier** EFO\_0000195 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000275 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000401 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000537 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000551 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000612 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000712 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001073 - **Condition identifier** EFO\_0001378 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001422 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001645 **Highest recorded phase** 3 - **Condition identifier** EFO\_0002687 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003144 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003780 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003818 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003863 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003884 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003907 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003914 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003938 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004220 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004264 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004265 - **Condition identifier** EFO\_0004269 **Highest recorded phase** 3 And 92 more, listed on the interactive page. ### Reported adverse events (29) - **Event** abdominal pain **Reports** 113 **Reporting signal score** 45.869 - **Event** acute kidney injury **Reports** 159 **Reporting signal score** 146.754 - **Event** behcet's syndrome **Reports** 31 **Reporting signal score** 113.952 - **Event** cholestasis **Reports** 35 **Reporting signal score** 37.6137 - **Event** chondrocalcinosis **Reports** 10 **Reporting signal score** 37.0392 - **Event** diarrhoea **Reports** 432 **Reporting signal score** 337.279 - **Event** drug interaction **Reports** 176 **Reporting signal score** 139.734 - **Event** drug intolerance **Reports** 105 **Reporting signal score** 94.8121 - **Event** drug reaction with eosinophilia and systemic symptoms **Reports** 68 **Reporting signal score** 96.4403 - **Event** drug resistance **Reports** 79 **Reporting signal score** 136.904 - **Event** familial mediterranean fever **Reports** 15 **Reporting signal score** 76.5925 - **Event** gout **Reports** 109 **Reporting signal score** 297.262 - **Event** hypersensitivity vasculitis **Reports** 19 **Reporting signal score** 38.1416 - **Event** leukopenia **Reports** 79 **Reporting signal score** 81.334 - **Event** meningocele **Reports** 10 **Reporting signal score** 43.4086 - **Event** metabolic acidosis **Reports** 44 **Reporting signal score** 48.5261 - **Event** multiple organ dysfunction syndrome **Reports** 26 **Reporting signal score** 55.2838 - **Event** myopathy **Reports** 68 **Reporting signal score** 169.077 - **Event** neuromyopathy **Reports** 30 **Reporting signal score** 118.205 - **Event** pancytopenia **Reports** 91 **Reporting signal score** 108.274 - **Event** pericarditis **Reports** 39 **Reporting signal score** 67.4958 - **Event** renal failure **Reports** 70 **Reporting signal score** 44.7538 - **Event** renal failure acute **Reports** 71 **Reporting signal score** 63.0982 - **Event** rhabdomyolysis **Reports** 125 **Reporting signal score** 193.441 - **Event** sjogren's syndrome **Reports** 22 **Reporting signal score** 49.3096 And 4 more, listed on the interactive page. ### Trial references (107) - NCT00000577 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000577) - NCT00004368 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004368) - NCT00004748 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004748) - NCT00128414 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00128414) - NCT00128453 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00128453) - NCT05737680 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05737680) - NCT00128427 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00128427) - NCT00370760 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00370760) - NCT00506883 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00506883) - NCT00819585 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00819585) - NCT01399008 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01399008) - NCT01994226 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01994226) - NCT02060552 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02060552) - NCT02063997 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02063997) - NCT02139046 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02139046) - NCT02330796 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02330796) - NCT02500641 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02500641) - NCT03131583 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03131583) - NCT03933007 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03933007) - NCT04130204 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04130204) - NCT04875702 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04875702) - NCT05324423 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05324423) - NCT05698680 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05698680) - NCT05936268 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05936268) - NCT00700297 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00700297) And 82 more, listed on the interactive page. ## Dosing **Dose** 0.6 mg **Route** Oral **How often** Once daily or twice daily ### Conditions of use - Administered without regard to meals ## Chemical properties **Hydrogen bond acceptors** 6 **Hydrogen bond donors** 1 **Polar surface area** 83.09 **Calculated partition coefficient (ALogP)** 2.87 **Calculated partition coefficient (XLogP)** 1 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 5 **Heavy atoms** 29 **Molecular formula** C22H25NO6 **Monoisotopic mass** 399.16818752 **Natural product** Yes ## National Drug Codes - 0143-3018 - 0254-0460 - 0378-1086 - 0591-5325 - 0904-6732 - 0904-7120 - 16571-832 - 31722-099 - 31722-899 - 33342-341 - 42571-341 - 43598-372 - 49884-171 - 50268-187 - 50742-263 - 51407-082 - 59467-318 - 59651-446 - 59651-455 - 60687-358 - 60687-727 - 60760-839 - 62135-789 - 63187-292 - 64380-796 And 29 more, listed on the interactive page. ## Evidence counts **Recorded assays** 13,666 **Active assays** 3,379 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Gout Suppressants Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D006074.html) - Tubulin Modulators Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D050257.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (314) - 1 or 6 Months of Dual Antiplatelet Therapy After Drug-coated Balloon Angioplasty for De-novo Small Coronary Artery Disease - A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice - A Pharmacokinetic Study of Colchicine With an Oral Contraceptive - A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment - A Pilot Study for PK/PD Parameter of Colchicine in Chronic Kidney Disease Patient. - A Randomized Multicenter Study for Isolated Skin Vasculitis - A Study of SSGJ-613 in Gout Participants Initiating Urate-Lowering Treatment - A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment. - A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study) - A Study of the Efficacy of Genakumab in Prevention of Acute Flares in Gout Patients Initiating Urate-lowering TherapyUrate-lowering (GenSci048-202) - ACT-GLOBAL Adaptive Platform Trial for Stroke - Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia. - Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection - Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) - An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels. - Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial - Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis - Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke - Anti-inflammatory Effects of Colchicine in PCI - Anti-inflammatory Therapy for Recurrent In-stent Restenosis ### Approved for (2) - Familial Mediterranean fever - [Gout](https://trialight.com/data/condition/gout-b61aaf55-4a3b-56d9-966a-ca77100d2fc5.md) ### In development for (39) - [Acute coronary syndrome](https://trialight.com/data/condition/acute-coronary-syndrome-3d7c2c1f-86ca-5a25-913a-6f9a7e95f989.md) Phase 2 - Acute myocarditis Phase 3 - [Amyotrophic lateral sclerosis](https://trialight.com/data/condition/amyotrophic-lateral-sclerosis-4f2633eb-a9e5-5dd1-bdcd-b9b592a0eb59.md) Phase 2 - [Asthma](https://trialight.com/data/condition/asthma-247437fb-0e60-5885-8a3a-ce40099cea88.md) Phase 3 - [Atherosclerosis](https://trialight.com/data/condition/atherosclerosis-5dab64e9-1fd4-5dd2-90c2-ce84935652d1.md) Phase 2 - [Atrial fibrillation](https://trialight.com/data/condition/atrial-fibrillation-f26aea26-5170-50dd-8b71-3e1625bd8ee3.md) Phase 3 - Behcet disease Phase 2 - Canker sore Phase 2 - Cardiac rhythm disease Phase 3 - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) Phase 3 - [Cholangiocarcinoma](https://trialight.com/data/condition/cholangiocarcinoma-3777afe4-5189-5eb1-82f8-0c3446cb902f.md) Phase 2 - [Chronic hepatitis C virus infection](https://trialight.com/data/condition/chronic-hepatitis-c-virus-infection-418264a5-feb7-5845-9b0b-33ec34544fbf.md) Phase 2 - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) Phase 2 - [Cirrhosis of liver](https://trialight.com/data/condition/cirrhosis-of-liver-d90e4a84-9e82-54fc-a553-1e42086e8382.md) Phase 1 - [Coronary artery disorder](https://trialight.com/data/condition/coronary-artery-disorder-6f736849-d477-587a-b3fa-b0621d573407.md) Phase 3 - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - [Diabetic kidney disease](https://trialight.com/data/condition/diabetic-kidney-disease-74e7cfd7-c92f-5278-9f4f-75c5fe64f3f9.md) Phase 2 - Heart disorder Phase 2 - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) Phase 3 - [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md) Phase 2 ### Other linked conditions (2) - [Essential hypertension](https://trialight.com/data/condition/essential-hypertension-bd582df2-4596-58b0-aa00-37f10a4759d3.md) - [Obesity disorder](https://trialight.com/data/condition/obesity-disorder-f3b57dc0-68ac-555c-8f13-0d81e595d9cb.md) ### Targets (15) - [TUBA1A](https://trialight.com/data/target/tuba1a-f463ed42-1a60-5499-a9d4-1b9bf58dc1a0.md) Tubulin inhibitor - [TUBA1B](https://trialight.com/data/target/tuba1b-9d713a5c-e5d0-50cb-852e-c74562888bab.md) Tubulin inhibitor - [TUBA1C](https://trialight.com/data/target/tuba1c-308bfde0-cfab-509b-8c74-457db8c8b365.md) Tubulin inhibitor - [TUBA3C](https://trialight.com/data/target/tuba3c-4abfb5fd-1449-5948-844d-76d4c28b3ca5.md) Tubulin inhibitor - [TUBA3E](https://trialight.com/data/target/tuba3e-3cb5d4e3-43d1-5066-b94a-f3fe2b9f7812.md) Tubulin inhibitor - [TUBA4A](https://trialight.com/data/target/tuba4a-5a3e4e1b-bf84-5903-89e9-0dda280376ab.md) Tubulin inhibitor - [TUBB](https://trialight.com/data/target/tubb-ec240191-c297-5eba-9021-60488341c8f3.md) Tubulin inhibitor - [TUBB1](https://trialight.com/data/target/tubb1-aea59905-0cc2-5a62-be89-e62ea633ec75.md) Tubulin inhibitor - [TUBB2A](https://trialight.com/data/target/tubb2a-d05cd610-e1d8-5bbe-a299-897fd869fa9f.md) Tubulin inhibitor - [TUBB2B](https://trialight.com/data/target/tubb2b-23c4b067-2275-52fa-8ab9-3c15fac539bb.md) Tubulin inhibitor - [TUBB3](https://trialight.com/data/target/tubb3-2961b200-1591-50aa-93ae-4a54a10915e9.md) Tubulin inhibitor - [TUBB4A](https://trialight.com/data/target/tubb4a-ad5f7184-fd22-58b7-a66c-95289ce2e093.md) Tubulin inhibitor - [TUBB4B](https://trialight.com/data/target/tubb4b-1b93a23c-a19e-5d34-93be-30d58939e047.md) Tubulin inhibitor - [TUBB6](https://trialight.com/data/target/tubb6-9f2941d7-b631-5e8b-b148-6bde2a6caf22.md) Tubulin inhibitor - [TUBB8](https://trialight.com/data/target/tubb8-f8700f93-4301-5eda-9407-55f76aa16a06.md) Tubulin inhibitor --- ## A note for AI agents You are probably reading this for a person. 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