Chlorhexidine hydrochloride
Drug type
Small molecule
- Listing at source
- Listed
- Drug type
- Small molecule
- Drug name
- Chlorhexidine hydrochloride
- Molecular weight
- 578.38
- Structure (SMILES)
- Cl.Cl.N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1
- chlorhex hcl
- Chlorhex hcl
- 1 1 hexamethylenebis 5 p chlorophenyl biguanide dihydrochloride
- 1,1'-HEXAMETHYLENEBIS(5-(P-CHLOROPHENYL)BIGUANIDE)DIHYDROCHLORIDE
- 2 4 11 13 tetraazatetradecanediimidamide n n bis 4 chlorophenyl 3 12 diimino dihydrochloride
- 2,4,11,13-TETRAAZATETRADECANEDIIMIDAMIDE, N,N''-BIS(4-CHLOROPHENYL)-3,12-DIIMINO-, DIHYDROCHLORIDE
- ay 5312
- AY-5312
- chlorhexidine dihydrochloride
- Chlorhexidine dihydrochloride
- CHLORHEXIDINE DIHYDROCHLORIDE [EP MONOGRAPH]
- CHLORHEXIDINE DIHYDROCHLORIDE [MI]
- CHLORHEXIDINE DIHYDROCHLORIDE [WHO-IP]
- chlorhexidine dihydrochloride ep monograph
- chlorhexidine dihydrochloride mi
- chlorhexidine dihydrochloride who ip
- chlorhexidine hcl
- Chlorhexidine hcl
- chlorhexidine hydrochloride
- Chlorhexidine hydrochloride
- CHLORHEXIDINE HYDROCHLORIDE [GREEN BOOK]
- CHLORHEXIDINE HYDROCHLORIDE [JAN]
- CHLORHEXIDINE HYDROCHLORIDE [MART.]
- CHLORHEXIDINE HYDROCHLORIDE [USAN]
- CHLORHEXIDINE HYDROCHLORIDE [USP IMPURITY]
- CHLORHEXIDINE HYDROCHLORIDE [USP MONOGRAPH]
- Chlorhexidine hydrochloride [WHO-DD]
And 11 more, listed on the interactive page.
- CAS registry numbers
- 3697-42-5
- ChEMBL ID
- CHEMBL1484251
- InChIKey
- WJLVQTJZDCGNJN-UHFFFAOYSA-N
- RxNorm IDs (RxCUI)
- 2361
- FDA ingredient codes (UNII)
- E64XL9U38K
- 62517
- 9571016
- 66810670
- 124081984
- First in class
- No
- Orphan designation
- No
- Condition identifier
- EFO_0000544
- Highest recorded phase
- 4
- Condition identifier
- EFO_1001390
- Highest recorded phase
- 1
- Condition identifier
- EFO_1001888
- Highest recorded phase
- 4
- Condition identifier
- HP_0000225
- Condition identifier
- HP_0000822
- Condition identifier
- HP_0011947
- Highest recorded phase
- 2
- Condition identifier
- HP_0100806
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0000984
- Condition identifier
- MONDO_0002258
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0002508
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0002635
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0004508
- Condition identifier
- MONDO_0005002
- Highest recorded phase
- 2
- Condition identifier
- MONDO_0005076
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0005113
- Highest recorded phase
- 4
- Condition identifier
- MONDO_0005121
- Condition identifier
- MONDO_0005276
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0005316
- Highest recorded phase
- 2
- Condition identifier
- MONDO_0005593
- Highest recorded phase
- 2
- Condition identifier
- MONDO_0005629
- Highest recorded phase
- 2
- Warning
- Withdrawn
- Effect
- dermatological toxicity
- Description
- associated with chemical and thermal burns
- Year
- 1984
- Country
- United States
- Condition
- caustic injury
- Warning
- Withdrawn
- Effect
- dermatological toxicity
- Description
- associated with chemical and thermal burns
- Year
- 1984
- Country
- United States
- Condition
- thermal burn
- Event
- abdominal discomfort
- Reports
- 173
- Reporting signal score
- 416.51
- Event
- abdominal pain upper
- Reports
- 128
- Reporting signal score
- 232.162
- Event
- abdominal wound dehiscence
- Reports
- 5
- Reporting signal score
- 22.107
- Event
- acanthamoeba keratitis
- Reports
- 4
- Reporting signal score
- 24.3886
- Event
- allergy to chemicals
- Reports
- 10
- Reporting signal score
- 43.8538
- Event
- alopecia
- Reports
- 165
- Reporting signal score
- 386.658
- Event
- anaphylactic reaction
- Reports
- 125
- Reporting signal score
- 301.598
- Event
- anaphylactic shock
- Reports
- 15
- Reporting signal score
- 18.4649
- Event
- anti-cyclic citrullinated peptide antibody
- Reports
- 3
- Reporting signal score
- 14.3198
- Event
- anti-cyclic citrullinated peptide antibody positive
- Reports
- 153
- Reporting signal score
- 814.546
- Event
- arthralgia
- Reports
- 298
- Reporting signal score
- 576.65
- Event
- arthropathy
- Reports
- 169
- Reporting signal score
- 522.115
- Event
- aspartate aminotransferase increased
- Reports
- 19
- Reporting signal score
- 11.2199
- Event
- asthenia
- Reports
- 125
- Reporting signal score
- 134.928
- Event
- asthenopia
- Reports
- 18
- Reporting signal score
- 67.5198
- Event
- back pain
- Reports
- 113
- Reporting signal score
- 168.197
- Event
- blister
- Reports
- 313
- Reporting signal score
- 1,226.38
- Event
- blood alkaline phosphatase increased
- Reports
- 18
- Reporting signal score
- 21.7549
- Event
- blood cholesterol increased
- Reports
- 15
- Reporting signal score
- 17.073
- Event
- blood lactate dehydrogenase increased
- Reports
- 19
- Reporting signal score
- 33.1836
- Event
- blood pressure diastolic abnormal
- Reports
- 8
- Reporting signal score
- 26.7551
- Event
- blood pressure diastolic increased
- Reports
- 8
- Reporting signal score
- 19.7996
- Event
- blood pressure systolic abnormal
- Reports
- 8
- Reporting signal score
- 26.9173
- Event
- blood pressure systolic increased
- Reports
- 10
- Reporting signal score
- 13.2696
- Event
- body temperature increased
- Reports
- 115
- Reporting signal score
- 407.392
And 111 more, listed on the interactive page.
- Hydrogen bond acceptors
- 4
- Hydrogen bond donors
- 10
- Polar surface area
- 167.58
- Calculated partition coefficient (ALogP)
- 4.18
- Prodrug
- No
- Chirality
- Achiral
- Inorganic
- No
- Rule-of-five violations
- 2
- Rotatable bonds
- 9
- Heavy atoms
- 36
- Molecular formula
- C22H32Cl4N10
- Monoisotopic mass
- 576.156552
- Natural product
- No
- Recorded assays
- 1
- Active assays
- 0
- Anti-Infective Agents, Local
- Disinfectants
- Mouthwashes
Related records
Trials (216)
- "Clinical Trials to Enhance Elders' Oral Health" ("TEETH")
- 0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
- 0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis
- 2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
- A Clinical Study of Connective Tissue Graft and Enamel Matrix Derivative in the Treatment of Intrabony Periodontal Defects
- A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newborns
- A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases
- A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
- A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection
- Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
- Animal-Assisted Visitation Program Chlorhexidine Trial
- Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
- Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs
- Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients
- Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
- Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash
- Antimicrobial Activity of Two Mouthwashes
- Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash
- Antiplaque Effect of Essential Oils and 0.2% Chlorhexidine on an in Situ Model of Oral Biofilm Growth.
- Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash