> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/chimpanzee-adenovirus-encoding-sars-cov-2-spike-glycoprotein-c67aa7ba-4ce2-445f-92fa-f1da4ae13917
> Record changed: 2026-10-13

# Chimpanzee adenovirus encoding sars-cov-2 spike glycoprotein

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

First approval year

2021

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

## Development status

**First approval year**

2021

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

**Drug name**

Chimpanzee adenovirus encoding sars-cov-2 spike glycoprotein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

### Brand names (2)

- Vaxzevria (previously covid-19 vaccine astrazeneca)
- vaxzevria previously covid 19 vaccine astrazeneca

### Other names (5)

- chimpanzee adenovirus encoding sars cov 2 spike glycoprotein
- Chimpanzee adenovirus encoding sars-cov-2 spike glycoprotein
- vaxzevria
- Vaxzevria
- Vaxzevria®

## Identifiers

**ChEMBL ID**

CHEMBL6068380

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068380)

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-vir-

### Mechanisms of action

- **Mechanism**  
Spike glycoprotein vaccine antigen

**Action type**  
VACCINE\_ANTIGEN

**Target**  
Spike glycoprotein

**Protein identifier**  
P0DTC2

### Open Targets mechanisms

- **Mechanism**  
Spike glycoprotein vaccine antigen

**Action type**  
VACCINE ANTIGEN

**Target**  
Spike glycoprotein

### Investigated indications (2)

- **Condition**  
Vaccination

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0004292

**Subject identifier**  
D014611
- **Condition**  
COVID-19

**Highest recorded phase**  
4

**Condition identifier**  
MONDO:0100096

**Subject identifier**  
D000086382

### Open Targets indications (2)

- **Condition identifier**  
MONDO\_0100096
- **Condition identifier**  
MONDO\_0100096

**Highest recorded phase**  
4

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (4)

- Booster Superiority Study of PTX-COVID19-B Compared to Vaxzevria® in Adults Aged 18 Years and Older
- Heterologous SARS-CoV-2 Vaccination With ChAdOx-1 and BNT162b2
- [Immunogenicity and Safety Study of SCB-2019 Vaccine as a Booster to COVID-19 Vaccine in Adults](https://trialight.com/data/trial/immunogenicity-and-safety-study-of-scb-2019-vaccine-as-a-569b39d4-e02c-4a04-96ec-a8fd8d54125b.md)
- Prospective Monitoring of Antibody Response Following COVID-19 Vaccination in Patients With Down Syndrome.

### Approved for (1)

- [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md)

---

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