> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/charcoal-activated-74974a11-0327-42be-ba92-123123e02c3a > Record changed: 2026-10-13 # Charcoal, activated Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) **Drug name** Charcoal, activated Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) **Molecular weight** 12.01 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) **Structure (SMILES)** These details could not be displayed. ### Other names (27) - 5 g charcoal powder - activated charcoal - Activated charcoal - Activated Charcoal - Activated Charcoal suspension - ast 120 - Ast 120 - AST-120 - AST-120 (Kremezin®) - carbo vegetabilis - Carbo vegetabilis - carbon - Carbon - carbon dioxide insufflation - Carbon dioxide insufflation - carbon medicinal - carbon suspension - carbon-dioxide insufflation - Carbon, medicinal - charcoal - Charcoal - charcoal activated - Charcoal, activated - medicinal carbon - Medicinal carbon And 2 more, listed on the interactive page. ## Identifiers **ChEMBL ID** CHEMBL2106049 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) **InChIKey** OKTJSMMVPCPJKN-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) **PubChem compound IDs** - 5462310 **RxNorm IDs (RxCUI)** - 272 ### ATC classification codes (2) - A07BA01 - A07BA51 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106049) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Investigated indications (15) - **Condition** Pulmonary Disease, Chronic Obstructive **Highest recorded phase** 1 **Condition identifier** EFO:0000341 **Subject identifier** D029424 - **Condition** Irritable Bowel Syndrome **Highest recorded phase** 2 **Condition identifier** EFO:0000555 **Subject identifier** D043183 - **Condition** Inflammatory Bowel Diseases **Highest recorded phase** 3 **Condition identifier** EFO:0003767 **Subject identifier** D015212 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 3 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Pouchitis **Highest recorded phase** 2 **Condition identifier** EFO:0003921 **Subject identifier** D019449 - **Condition** Gastroesophageal Reflux **Highest recorded phase** 2 **Condition identifier** EFO:0003948 **Subject identifier** D005764 - **Condition** Sleep Initiation and Maintenance Disorders **Highest recorded phase** 1 **Condition identifier** EFO:0004698 **Subject identifier** D007319 - **Condition** Brain Diseases **Highest recorded phase** 2 **Condition identifier** HP:0001298 **Subject identifier** D001927 - **Condition** Stomach Neoplasms **Highest recorded phase** 3 **Condition identifier** MONDO:0001056 **Subject identifier** D013274 - **Condition** Depressive Disorder, Major **Highest recorded phase** 1 **Condition identifier** MONDO:0002009 **Subject identifier** D003865 - **Condition** Asthma **Highest recorded phase** 1 **Condition identifier** MONDO:0004979 **Subject identifier** D001249 - **Condition** Diabetes Mellitus, Type 2 **Highest recorded phase** 1 **Condition identifier** MONDO:0005148 **Subject identifier** D003924 - **Condition** Hypersensitivity **Highest recorded phase** 1 **Condition identifier** MONDO:0005271 **Subject identifier** D006967 - **Condition** Multiple Sclerosis **Highest recorded phase** 3 **Condition identifier** MONDO:0005301 **Subject identifier** D009103 - **Condition** Lung Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0008903 **Subject identifier** D008175 ### Open Targets indications (43) - **Condition identifier** EFO\_0000341 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000555 - **Condition identifier** EFO\_0003767 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003884 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003921 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003948 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009909 **Highest recorded phase** 2 - **Condition identifier** HP\_0001298 **Highest recorded phase** 2 - **Condition identifier** HP\_0001873 - **Condition identifier** HP\_0001873 **Highest recorded phase** 0 - **Condition identifier** HP\_0012393 - **Condition identifier** HP\_0012393 **Highest recorded phase** 0 - **Condition identifier** MONDO\_0000328 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0001056 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0001056 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0002108 - **Condition identifier** MONDO\_0002108 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0002492 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0002974 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0004979 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0004992 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005011 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005052 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005101 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005136 **Highest recorded phase** 2 And 18 more, listed on the interactive page. ### Reported adverse events (40) - **Event** acute respiratory distress syndrome **Reports** 5 **Reporting signal score** 14.6469 - **Event** areflexia **Reports** 2 **Reporting signal score** 6.8474 - **Event** beta haemolytic streptococcal infection **Reports** 2 **Reporting signal score** 8.60525 - **Event** bezoar **Reports** 3 **Reporting signal score** 14.2136 - **Event** blood creatine phosphokinase mb **Reports** 1 **Reporting signal score** 6.07038 - **Event** blood osmolarity increased **Reports** 2 **Reporting signal score** 10.9579 - **Event** bradycardia **Reports** 15 **Reporting signal score** 34.2789 - **Event** bundle branch block right **Reports** 2 **Reporting signal score** 5.59492 - **Event** cardiac arrest **Reports** 7 **Reporting signal score** 16.373 - **Event** cardiogenic shock **Reports** 8 **Reporting signal score** 28.1914 - **Event** cardioplegia **Reports** 1 **Reporting signal score** 7.51009 - **Event** coma **Reports** 7 **Reporting signal score** 14.2995 - **Event** coma scale abnormal **Reports** 5 **Reporting signal score** 19.7591 - **Event** compartment syndrome **Reports** 5 **Reporting signal score** 21.2849 - **Event** congestive hepatopathy **Reports** 1 **Reporting signal score** 5.61411 - **Event** depressed level of consciousness **Reports** 6 **Reporting signal score** 11.4135 - **Event** electrocardiogram qrs complex prolonged **Reports** 2 **Reporting signal score** 5.51134 - **Event** hyperkalaemia **Reports** 8 **Reporting signal score** 17.8529 - **Event** hypernatraemia **Reports** 2 **Reporting signal score** 5.73879 - **Event** hypotension **Reports** 14 **Reporting signal score** 18.1267 - **Event** hypothermia **Reports** 3 **Reporting signal score** 7.31786 - **Event** ileus **Reports** 5 **Reporting signal score** 14.0643 - **Event** lactic acidosis **Reports** 9 **Reporting signal score** 22.2016 - **Event** left ventricular dysfunction **Reports** 4 **Reporting signal score** 12.5731 - **Event** metabolic acidosis **Reports** 7 **Reporting signal score** 16.5591 And 15 more, listed on the interactive page. ### Trial references (28) - NCT00321412 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00321412) - NCT00500682 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00500682) - NCT00501046 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00501046) - NCT04311645 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04311645) - NCT00558038 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00558038) - NCT00867698 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00867698) - NCT00583076 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00583076) - NCT00583531 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00583531) - NCT00583128 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00583128) - NCT00587275 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00587275) - NCT01236105 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01236105) - NCT01257191 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01257191) - NCT01389752 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01389752) - NCT01766843 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01766843) - NCT01856621 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01856621) - NCT02237508 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02237508) - NCT02359292 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02359292) - NCT02631941 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02631941) - NCT03073057 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03073057) - NCT01863888 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01863888) - NCT06141473 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06141473) - NCT02123407 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02123407) - NCT05229874 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05229874) - NCT02512302 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02512302) - NCT02691325 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02691325) And 3 more, listed on the interactive page. ## Chemical properties **Hydrogen bond acceptors** 0 **Hydrogen bond donors** 0 **Polar surface area** 0 **Calculated partition coefficient (ALogP)** 0.08 **Calculated partition coefficient (XLogP)** 0.6 **Prodrug** No **Chirality** Achiral **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 0 **Heavy atoms** 1 **Molecular formula** C **Monoisotopic mass** 12 **Natural product** No ## Related records ### Trials (86) - 11C- and 18F-Choline PET/MR Imaging for Prostate Cancer - 18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant - A Clinical Study to Evaluate the Pharmacokinetics and the Absolute Bioavailability of SRT2104 Given as a 250mg Oral Suspension and Intravenous Microdose of 100 µg Carbon-14 Radio-labeled SRT2104 in Healthy Male Subjects - A Clinical Study to Evaluate Z7200 (Budesonide/Formoterol) Pharmacokinetics Profile in Healthy Volunteers - A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic Renal Failure - A Pilot Feasibility Study of Activated Charcoal in Healthy Volunteers - A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease (EPPIC-1) - A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease Including Assessment of Quality of Life (EPPIC-2) - A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819 - A Study to Assess the Absorption, Metabolism and Excretion of \[14C\]-ANG-3777 - A Study to Compare the Effects of Different Sized Particles on Cells in the Nose - A Study to Evaluate the Effect of Activated Charcoal on the Absorption of LY2216684 in Healthy Subjects - A Study to Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants - Absorption of Indacaterol and Glycopyrronium From Ultibro Breezhaler - Activated CHARcoal in Poisoned Patient - Pilot Trial - Activated Charcoal Use in Chronic Kidney Disease Patients - Activates Charcoal for Patients Undergoing Invasive Procedure Delayed Due to Direct Oral Anticoagulants - An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy - Application of Preoperative Axillary Lymph Node Marking With Nano-Carbon in Breast Cancer Patients Before Neoadjuvant Chemotherapy - Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study ### In development for (16) - Allergic disease Phase 1 - [Asthma](https://trialight.com/data/condition/asthma-247437fb-0e60-5885-8a3a-ce40099cea88.md) Phase 1 - [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md) Phase 2 - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) Phase 3 - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) Phase 1 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 3 - Gastroesophageal reflux disease Phase 2 - [Inflammatory bowel disease](https://trialight.com/data/condition/inflammatory-bowel-disease-619080ac-2d43-5ad3-b078-9699e1241655.md) Phase 3 - [Insomnia](https://trialight.com/data/condition/insomnia-57f6af86-fd71-567b-813f-5867cfd4790c.md) Phase 1 - [Irritable bowel syndrome](https://trialight.com/data/condition/irritable-bowel-syndrome-10830a51-118b-59c5-8ff4-5e11dbe81c01.md) Phase 2 - [Lung cancer](https://trialight.com/data/condition/lung-cancer-c4ca1fe0-9b3d-5957-a668-2d6cf26bd16a.md) Phase 2 - [Major depressive disorder](https://trialight.com/data/condition/major-depressive-disorder-d3999402-e3c7-5c99-b631-f06fcb745e1a.md) Phase 1 - [Multiple sclerosis](https://trialight.com/data/condition/multiple-sclerosis-62806c95-fe1b-529e-bd16-95cb92d15375.md) Phase 3 - [Parkinson disease](https://trialight.com/data/condition/parkinson-disease-a117728d-ad75-551b-9b20-fffa9a2305ac.md) Phase 1 - Pouchitis Phase 2 - [Type 2 diabetes mellitus](https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9.md) Phase 1 ### Other linked conditions (1) - [Thyroid cancer](https://trialight.com/data/condition/thyroid-cancer-44afb6a8-b88e-5e18-b9fd-7b51661c2c23.md) --- ## A note for AI agents You are probably reading this for a person. 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