> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/cannabidiol-e1ac1a9a-1111-460c-8a8f-5216571adce8 > Record changed: 2026-11-04 # Cannabidiol Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) First approval year 2018 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) ## Development status **First approval year** 2018 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **Drug name** Cannabidiol Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **Molecular weight** 314.47 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **Structure (SMILES)** C=C(C)\[C@@H\]1CCC(C)=C\[C@H\]1c1c(O)cc(CCCCC)cc1O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) ### Brand names (4) - epidiolex - Epidiolex - epidyolex - Epidyolex ### Other names (232) - .delta.1(2)-trans-cannabidiol - (-)-cannabidiol - (-)-cbd - (-)-trans-cannabidiol - 100 mg Cannabidiol (CBD) - 100 mg cannabidiol cbd - 1200 mg cannabidiol - 1200 mg Cannabidiol - 300 mg cannabidiol - 300 mg Cannabidiol - 300 mg Cannabidiol (CBD) oil - 300 mg cannabidiol cbd oil - 400 mg cannabidiol - 400 mg Cannabidiol - 50 mg Cannabidiol (CBD) - 50 mg cannabidiol cbd - 600 mg cannabidiol - 600 mg Cannabidiol - 600 mg cannabidiol (CBD) - 600 mg cannabidiol cbd - 800 mg cannabidiol - 800 mg Cannabidiol - arm 2 - Arm 2 - ARM 2 And 207 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 13956-29-1 **ChEMBL ID** CHEMBL190461 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **InChIKey** QHMBSVQNZZTUGM-ZWKOTPCHSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) **PubChem compound IDs** - 644019 **RxNorm IDs (RxCUI)** - 2045371 **FDA ingredient codes (UNII)** - 19GBJ60SN5 ### ATC classification codes (2) - N03AX - N03AX24 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL190461) ## Regulatory information ### United States **Applicant** JAZZ PHARMS RES **Approval date** 25 Jun 2018 **Application number** NDA210365 ### European Union **Status** Authorised **Status date** 19 Sept 2019 **Authorisation date** 19 Sept 2019 **Approved indications** Epidyolex is indicated for use as adjunctive therapy of seizures associated with Lennox Gastaut syndrome (LGS) or Dravet syndrome (DS), in conjunction with clobazam, for patients 2 years of age and older. **Product number** EMEA/H/C/004675 **Authorisation holder** Jazz Pharmaceuticals Ireland Limited **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Epilepsies, Myoclonic - Lennox Gastaut Syndrome European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/epidyolex) ### Other regulatory facts **Patents** 32 **Designations** 6 **Earliest recorded loss of exclusivity** 1 Mar 2041 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** Yes **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Approval status **United States (FDA)** Approved **European Union (EMA)** Authorised ## Pharmacology ### Drug classification **Pharmacology name** cannabidiol **Type** Natural product **Drug name stem** \-nab- **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (14) - **Action** Activation **Action type** ACTIVATION **Target** TRPV2 **Gene symbol** TRPV2 **Protein identifier** Q9Y5S1 **Median affinity** 4.5 **Affinity units** pEC50 - **Action** Antagonist **Action type** Antagonist **Target** GPR55 **Gene symbol** GPR55 **Protein identifier** Q9Y2T6 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.1 **Gene symbol** SCN1A **Protein identifier** P35498 **Median affinity** 4.9 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.1 **Gene symbol** SCN1A **Protein identifier** P35498 **Median affinity** 5.54 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.4 **Gene symbol** SCN4A **Protein identifier** P35499 **Median affinity** 5.72 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.4 **Gene symbol** SCN4A **Protein identifier** P35499 **Median affinity** 5 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.5 **Gene symbol** SCN5A **Protein identifier** Q14524 **Median affinity** 5.42 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.7 **Gene symbol** SCN9A **Protein identifier** Q15858 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.2 **Gene symbol** SCN2A **Protein identifier** Q99250 **Median affinity** 5.54 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.3 **Gene symbol** SCN3A **Protein identifier** Q9NY46 **Median affinity** 5.48 **Affinity units** pIC50 - **Action** Channel blocker **Action type** Channel blocker **Target** Nav1.6 **Gene symbol** SCN8A **Protein identifier** Q9UQD0 **Median affinity** 5.52 **Affinity units** pIC50 - **Mechanism** Cannabinoid CB1 receptor negative allosteric modulator **Action type** NEGATIVE\_ALLOSTERIC\_MODULATOR **Target** Cannabinoid receptor 1 **Protein identifier** P21554 - **Action** Negative **Action type** NEGATIVE **Target** CB1 receptor **Gene symbol** CNR1 **Protein identifier** P21554 - **Action** Partial agonist **Action type** PARTIAL\_AGONIST **Target** GPR18 **Gene symbol** GPR18 **Protein identifier** Q14330 **Median affinity** 4.29 **Affinity units** pEC50 ### Open Targets mechanisms - **Mechanism** Cannabinoid CB1 receptor negative allosteric modulator **Action type** NEGATIVE ALLOSTERIC MODULATOR **Target** Cannabinoid receptor 1 ### DrugCentral mechanisms (4) - **Action type** ACTIVATOR **Gene symbol** TRPV2 **Protein identifier** Q9Y5S1 **Organism** Homo sapiens **Target development level** Chemical evidence - **Action type** Agonist **Gene symbol** GPR18 **Protein identifier** Q14330 **Organism** Homo sapiens **Target development level** Biological evidence - **Action type** Antagonist **Gene symbol** GPR55 **Protein identifier** Q9Y2T6 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** TRPV1 **Protein identifier** Q8NER1 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (90) - **Condition** HIV Infections **Highest recorded phase** 2 **Condition identifier** EFO:0000180 **Subject identifier** D015658 - **Condition** Crohn Disease **Highest recorded phase** 2 **Condition identifier** EFO:0000384 **Subject identifier** D003424 - **Condition** Epilepsy **Highest recorded phase** 4 **Condition identifier** EFO:0000474 **Subject identifier** D004827 - **Condition** Glioblastoma **Highest recorded phase** 2 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Hypertension **Highest recorded phase** 1 **Condition identifier** EFO:0000537 **Subject identifier** D006973 - **Condition** Wounds and Injuries **Highest recorded phase** 2 **Condition identifier** EFO:0000546 **Subject identifier** D014947 - **Condition** Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Prostatic Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Mental Disorders **Highest recorded phase** 2 **Condition identifier** EFO:0000677 **Subject identifier** D001523 - **Condition** Arthritis, Rheumatoid **Highest recorded phase** 2 **Condition identifier** EFO:0000685 **Subject identifier** D001172 - **Condition** Colitis, Ulcerative **Highest recorded phase** 2 **Condition identifier** EFO:0000729 **Subject identifier** D003093 - **Condition** HIV Infections **Highest recorded phase** 2 **Condition identifier** EFO:0000764 **Subject identifier** D015658 - **Condition** Endometriosis **Highest recorded phase** 2 **Condition identifier** EFO:0001065 **Subject identifier** D004715 - **Condition** Stress Disorders, Post-Traumatic **Highest recorded phase** 2 **Condition identifier** EFO:0001358 **Subject identifier** D013313 - **Condition** Cocaine-Related Disorders **Highest recorded phase** 2 **Condition identifier** EFO:0002610 **Subject identifier** D019970 - **Condition** Peripheral Nervous System Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0003100 **Subject identifier** D010523 - **Condition** Essential Tremor **Highest recorded phase** 1 **Condition identifier** EFO:0003108 **Subject identifier** D020329 - **Condition** Heart Failure **Highest recorded phase** 1 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Child Development Disorders, Pervasive **Highest recorded phase** 2 **Condition identifier** EFO:0003756 **Subject identifier** D002659 - **Condition** Autistic Disorder **Highest recorded phase** 2 **Condition identifier** EFO:0003758 **Subject identifier** D001321 - **Condition** Tobacco Use Disorder **Highest recorded phase** 2 **Condition identifier** EFO:0003768 **Subject identifier** D014029 - **Condition** Arthritis, Psoriatic **Highest recorded phase** 2 **Condition identifier** EFO:0003778 **Subject identifier** D015535 - **Condition** Motor Neuron Disease **Highest recorded phase** 3 **Condition identifier** EFO:0003782 **Subject identifier** D016472 - **Condition** Pain **Highest recorded phase** 3 **Condition identifier** EFO:0003843 **Subject identifier** D010146 - **Condition** Substance-Related Disorders **Highest recorded phase** 0.5 **Condition identifier** EFO:0003890 **Subject identifier** D019966 And 65 more, listed on the interactive page. ### Open Targets indications (256) - **Condition identifier** EFO\_0000180 - **Condition identifier** EFO\_0000384 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000474 - **Condition identifier** EFO\_0000519 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000546 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000649 - **Condition identifier** EFO\_0000677 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000685 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000729 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000764 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001065 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001358 **Highest recorded phase** 2 - **Condition identifier** EFO\_0002610 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003015 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003100 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003108 - **Condition identifier** EFO\_0003144 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003756 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003768 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003890 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003894 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003931 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004143 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004149 **Highest recorded phase** 2 And 231 more, listed on the interactive page. ### Reported adverse events (37) - **Event** abnormal behaviour **Reports** 100 **Reporting signal score** 93.947 - **Event** aggression **Reports** 208 **Reporting signal score** 286.569 - **Event** agitation **Reports** 175 **Reporting signal score** 140.15 - **Event** alcohol abuse **Reports** 66 **Reporting signal score** 190.152 - **Event** anaemia **Reports** 7 **Reporting signal score** 80.2939 - **Event** arthralgia **Reports** 22 **Reporting signal score** 79.8456 - **Event** atonic seizures **Reports** 28 **Reporting signal score** 93.2757 - **Event** behaviour disorder **Reports** 36 **Reporting signal score** 77.8011 - **Event** change in seizure presentation **Reports** 36 **Reporting signal score** 151.939 - **Event** coma **Reports** 115 **Reporting signal score** 95.2776 - **Event** decreased appetite **Reports** 210 **Reporting signal score** 84.9525 - **Event** diarrhoea **Reports** 625 **Reporting signal score** 211.76 - **Event** drooling **Reports** 42 **Reporting signal score** 73.6627 - **Event** drug abuse **Reports** 466 **Reporting signal score** 866.637 - **Event** drug dependence **Reports** 207 **Reporting signal score** 374.314 - **Event** drug use disorder **Reports** 41 **Reporting signal score** 77.2603 - **Event** dyspnoea **Reports** 58 **Reporting signal score** 87.2181 - **Event** generalised tonic-clonic seizure **Reports** 106 **Reporting signal score** 165.111 - **Event** headache **Reports** 68 **Reporting signal score** 73.3965 - **Event** hypersomnia **Reports** 67 **Reporting signal score** 88.492 - **Event** hypotension **Reports** 6 **Reporting signal score** 69.7816 - **Event** insurance issue **Reports** 37 **Reporting signal score** 83.6664 - **Event** irritability **Reports** 108 **Reporting signal score** 79.1988 - **Event** lethargy **Reports** 130 **Reporting signal score** 95.1143 - **Event** miosis **Reports** 73 **Reporting signal score** 121.755 And 12 more, listed on the interactive page. ### Trial references (190) - NCT00309413 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00309413) - NCT00588731 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00588731) - NCT00628290 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00628290) - NCT00916201 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00916201) - NCT01491490 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01491490) - NCT02006628 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02006628) - NCT02051387 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02051387) - NCT02088060 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02088060) - NCT02504151 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02504151) - NCT02926859 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02926859) - NCT04421456 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04421456) - NCT01037322 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01037322) - NCT01562314 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01562314) - NCT04056442 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04056442) - NCT01284634 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01284634) - NCT01311778 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01311778) - NCT01605539 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01605539) - NCT02539823 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02539823) - NCT04238754 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04238754) - NCT01385124 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01385124) - NCT01596075 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01596075) - NCT02478424 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02478424) - NCT03840512 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03840512) - NCT01502046 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01502046) - NCT01776970 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01776970) And 165 more, listed on the interactive page. ## Dosing **Dose** 2.5 mg/kg **Route** Oral **How often** Twice daily ## Chemical properties **Hydrogen bond acceptors** 2 **Hydrogen bond donors** 2 **Polar surface area** 40.46 **Calculated partition coefficient (ALogP)** 5.85 **Calculated partition coefficient (XLogP)** 6.5 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 1 **Rotatable bonds** 6 **Heavy atoms** 23 **Molecular formula** C21H30O2 **Monoisotopic mass** 314.224580195 **Natural product** Yes ## National Drug Codes - 70127-100 ## Evidence counts **Recorded assays** 908 **Active assays** 197 ### Active assay types (2) - Confirmatory - Other ## Pharmacologic actions - Anticonvulsants Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000927.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (303) - 5-Way Crossover Study to Compare the Safety, Tolerability and Pharmacokinetics of New Oral Cannabinoid Formulations Administered as Single Doses, With Buccal Sativex®, in Healthy Volunteers - A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients - A Clinical Trial on the Antipsychotic Properties of Cannabidiol - A Double-Blind Trial to Evaluate Efficacy and Safety of Cannabidiol as an add-on Therapy for Treatment in Refractory Epilepsy - A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis - A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol As a Treatment for Acutely Ill Schizophrenic Patients - A Long-term Safety Study of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome - A Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions - A Phase 2a Study to Evaluate the Safety and Efficacy of Cannabidiol Only as Maintenance Therapy and Steroid Sparing in Patients With Stable Autoimmune Hepatitis - A Pilot Study of GWP42003 in the Symptomatic Treatment of Ulcerative Colitis (GWID10160) - A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6) - A Randomized Controlled Trial of Oral CBD for the Treatment of Upper Extremity Musculoskeletal Pain - A Study of Cannabidiol in Young Adult Cannabis Users - A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain - A Study of GWP42003 as Adjunctive Therapy in the First Line Treatment of Schizophrenia or Related Psychotic Disorder - A Study of Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy - A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies - A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease - A Study of Tolerability and Efficacy of Cannabidiol on Tremor in Parkinson's Disease - A Study to Assess Cannabidiol Oral Solution With Vigabatrin as Initial Therapy in Participants With Infantile Spasms ### Approved for (7) - Dravet syndrome - Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy - [Epilepsy](https://trialight.com/data/condition/epilepsy-633a5321-bf08-5a6b-8459-d44b2b00904e.md) - Hamartoma - Lennox-Gastaut syndrome - Myoclonic epilepsy - [Visual epilepsy](https://trialight.com/data/condition/visual-epilepsy-9eee333f-f968-5e66-b952-f1f9696c6533.md) ### In development for (132) - 22q11.2 deletion syndrome Phase 2 - [Acne](https://trialight.com/data/condition/acne-02478aa3-966b-5ffb-a257-6dbe85c14e58.md) Phase 2 - Acute graft versus host disease Phase 2 - Acute myocarditis Phase 2 - Agoraphobia Phase 3 - [Alcohol abuse](https://trialight.com/data/condition/alcohol-abuse-de2eaa0d-f882-51b6-befd-e62533fe8ee1.md) Phase 2 - Alcohol dependence Phase 2 - Alcohol withdrawal Phase 2 - Alexithymia Phase 2 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 2 - [Amyotrophic lateral sclerosis](https://trialight.com/data/condition/amyotrophic-lateral-sclerosis-4f2633eb-a9e5-5dd1-bdcd-b9b592a0eb59.md) Phase 3 - [Androgenetic alopecia](https://trialight.com/data/condition/androgenetic-alopecia-8971c9fa-6fd1-50f4-96d4-6f14f6edcec4.md) Phase 1 - Anorexia nervosa Early phase 1 - Anxiety Phase 2 - [Anxiety disorder](https://trialight.com/data/condition/anxiety-disorder-d84a28fc-7045-53b8-a1b6-52babcd37d08.md) Phase 1 - [Arthritic joint disease](https://trialight.com/data/condition/arthritic-joint-disease-594ede40-773b-5c20-afc1-eb18dabbe039.md) Phase 2 - [Atopic eczema](https://trialight.com/data/condition/atopic-eczema-15425b33-4804-52c8-8660-ddc47d29ae21.md) Phase 3 - Attention deficit-hyperactivity disorder Phase 2 - Autism Phase 2 - Autism spectrum disorder Phase 2 ### Other linked conditions (4) - [Mood disorder](https://trialight.com/data/condition/mood-disorder-00c37338-ecb8-5997-bb93-d0ec3e6e3573.md) - Red-green color blindness - Tic disorder - Urolithiasis ### Targets (12) - [CNR1](https://trialight.com/data/target/cnr1-48d3113c-29b0-54a7-95e5-e98fe846a8e6.md) Cannabinoid CB1 receptor negative allosteric modulator - [GPR18](https://trialight.com/data/target/gpr18-05356393-ebec-5cf1-b9b4-c5d0f904e51a.md) - [GPR55](https://trialight.com/data/target/gpr55-de853285-7ef9-5467-bba6-107deaf3f671.md) - [SCN1A](https://trialight.com/data/target/scn1a-3473d408-b191-588e-8a54-6ea744fc0b86.md) - [SCN2A](https://trialight.com/data/target/scn2a-58945297-e1b4-5bf0-977c-fff5460c4bc5.md) - [SCN3A](https://trialight.com/data/target/scn3a-312e048c-0a82-5193-94d1-473a98b97a6e.md) - [SCN4A](https://trialight.com/data/target/scn4a-49bb6125-30fd-58f5-8275-868382aee1cb.md) - [SCN5A](https://trialight.com/data/target/scn5a-b122849c-977b-5d4c-a790-0245f1654eb5.md) - [SCN8A](https://trialight.com/data/target/scn8a-05beb79a-ca39-5d8d-a99b-ee0fd0d5e8c4.md) - [SCN9A](https://trialight.com/data/target/scn9a-6d55e0b8-9c24-5570-a1c0-5445020a13bf.md) - [TRPV1](https://trialight.com/data/target/trpv1-ca64e282-0693-5882-a5bc-8b93d8310d3a.md) - [TRPV2](https://trialight.com/data/target/trpv2-0b9b19ad-a0c9-5902-b7ee-c9fd4ba76ca2.md) --- ## A note for AI agents You are probably reading this for a person. 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