> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/camrelizumab-db95676a-3681-47ee-8647-408fc9391e28
> Record changed: 2026-11-04

# Camrelizumab

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

Drug type

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

## Names and chemistry

**Drug type**

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

**Drug name**

Camrelizumab

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

### Other names (78)

- anti pd 1 monoclonal antibody shr 1210
- ANTI-PD-1 MONOCLONAL ANTIBODY SHR-1210
- apatinib combined with camrelizumab
- apatinib combined with shr 1210 injection
- bevacizumab and camrelizumab
- biological camrelizumab
- Biological: Camrelizumab
- camrelizumab
- Camrelizumab
- Camrelizumab (SHR-1210)
- camrelizumab \[INN\]
- Camrelizumab \[WHO-DD\]
- camrelizumab 200mg
- Camrelizumab 200mg
- camrelizumab and bevacizumab
- camrelizumab and cetuximab
- camrelizumab and decitabine
- camrelizumab famitinib
- camrelizumab fluzoparib
- camrelizumab for injection
- camrelizumab for Injection
- Camrelizumab for injection
- Camrelizumab for injection (200 mg, iv)
- camrelizumab for injection 200 mg iv
- camrelizumab gemcitabin cisplatin

And 53 more, listed on the interactive page.

## Identifiers

**CAS registry numbers**

- 1798286-48-2

**ChEMBL ID**

CHEMBL4297715

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297715)

**FDA ingredient codes (UNII)**

- 73096E137E

## Regulatory information

### Other regulatory facts

**Patents**

0

**Designations**

1

**First in class**

No

**Fast track**

No

**Breakthrough designation**

No

**Orphan designation**

No

**Priority review**

No

**Orphan exclusivity**

No

**Accelerated approval**

No

## Pharmacology

### Drug classification

**Pharmacology name**

camrelizumab

**Type**

Antibody

**Drug name stem**

\-mab; -mab

**Approval recorded by Guide to Pharmacology**

Yes

### Mechanisms of action

- **Mechanism**  
Programmed cell death protein 1 antagonist

**Action type**  
Antagonist

**Target**  
Programmed cell death protein 1

**Protein identifier**  
Q15116

### Open Targets mechanisms

- **Mechanism**  
Programmed cell death protein 1 antagonist

**Action type**  
Antagonist

**Target**  
Programmed cell death protein 1

### Investigated indications (69)

- **Condition**  
Stomach Neoplasms

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000178

**Subject identifier**  
D013274
- **Condition**  
Carcinoma, Squamous Cell

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000181

**Subject identifier**  
D002294
- **Condition**  
Carcinoma, Hepatocellular

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000182

**Subject identifier**  
D006528
- **Condition**  
Hodgkin Disease

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000183

**Subject identifier**  
D006689
- **Condition**  
Squamous Cell Carcinoma of Head and Neck

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000199

**Subject identifier**  
D000077195
- **Condition**  
Lymphoma, T-Cell, Peripheral

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000211

**Subject identifier**  
D016411
- **Condition**  
Leukemia, Myeloid, Acute

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000222

**Subject identifier**  
D015470
- **Condition**  
Urinary Bladder Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000294

**Subject identifier**  
D001749
- **Condition**  
Carcinoma, Renal Cell

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000349

**Subject identifier**  
D002292
- **Condition**  
Colorectal Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000365

**Subject identifier**  
D015179
- **Condition**  
Lymphoma, Large B-Cell, Diffuse

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000403

**Subject identifier**  
D016403
- **Condition**  
Stomach Neoplasms

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000503

**Subject identifier**  
D013274
- **Condition**  
Glioblastoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000519

**Subject identifier**  
D005909
- **Condition**  
Adenocarcinoma of Lung

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000571

**Subject identifier**  
D000077192
- **Condition**  
Lymphoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000574

**Subject identifier**  
D008223
- **Condition**  
Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369
- **Condition**  
Osteosarcoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000637

**Subject identifier**  
D012516
- **Condition**  
Carcinoma, Renal Cell

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000681

**Subject identifier**  
D002292
- **Condition**  
Sarcoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000691

**Subject identifier**  
D012509
- **Condition**  
Small Cell Lung Carcinoma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000702

**Subject identifier**  
D055752
- **Condition**  
Carcinoma, Squamous Cell

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000707

**Subject identifier**  
D002294
- **Condition**  
Carcinoma, Squamous Cell

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000708

**Subject identifier**  
D002294
- **Condition**  
Melanoma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000756

**Subject identifier**  
D008545
- **Condition**  
Uterine Cervical Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0001061

**Subject identifier**  
D002583
- **Condition**  
Lung Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0001071

**Subject identifier**  
D008175

And 44 more, listed on the interactive page.

### Open Targets indications (143)

- **Condition identifier**  
EFO\_0000178

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000181

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000182

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000183
- **Condition identifier**  
EFO\_0000199

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000294
- **Condition identifier**  
EFO\_0000349

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000403

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000503

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000519

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000574

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000616

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000637

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000681

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000691

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000702

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000707

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000708

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000756

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0001071

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0002618

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0002916

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0002938

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0003060

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0003868

**Highest recorded phase**  
1

And 118 more, listed on the interactive page.

### Reported adverse events (74)

- **Event**  
abdominal infection

**Reports**  
3

**Reporting signal score**

11.7002
- **Event**  
abdominal pain

**Reports**  
15

**Reporting signal score**

14.4672
- **Event**  
acute graft versus host disease in intestine

**Reports**  
2

**Reporting signal score**

7.81618
- **Event**  
acute graft versus host disease in liver

**Reports**  
2

**Reporting signal score**

9.33056
- **Event**  
acute graft versus host disease in skin

**Reports**  
2

**Reporting signal score**

6.29562
- **Event**  
adrenal insufficiency

**Reports**  
4

**Reporting signal score**

9.32056
- **Event**  
alanine aminotransferase increased

**Reports**  
25

**Reporting signal score**

57.462
- **Event**  
alopecia

**Reports**  
7

**Reporting signal score**

6.72199
- **Event**  
anaemia

**Reports**  
38

**Reporting signal score**

69.9507
- **Event**  
ascites

**Reports**  
6

**Reporting signal score**

11.5164
- **Event**  
aspartate aminotransferase increased

**Reports**  
24

**Reporting signal score**

56.8809
- **Event**  
blood bilirubin increased

**Reports**  
9

**Reporting signal score**

19.6053
- **Event**  
blood creatinine increased

**Reports**  
7

**Reporting signal score**

8.62888
- **Event**  
cardiotoxicity

**Reports**  
3

**Reporting signal score**

6.90016
- **Event**  
cerebral radiation injury

**Reports**  
1

**Reporting signal score**

7.873
- **Event**  
constipation

**Reports**  
12

**Reporting signal score**

12.5097
- **Event**  
decreased appetite

**Reports**  
30

**Reporting signal score**

58.0453
- **Event**  
dermatitis

**Reports**  
5

**Reporting signal score**

11.7972
- **Event**  
diarrhoea

**Reports**  
39

**Reporting signal score**

42.456
- **Event**  
disease progression

**Reports**  
9

**Reporting signal score**

10.8563
- **Event**  
drug-induced liver injury

**Reports**  
6

**Reporting signal score**

10.6525
- **Event**  
endocrine toxicity

**Reports**  
1

**Reporting signal score**

6.48713
- **Event**  
fatigue

**Reports**  
34

**Reporting signal score**

30.4141
- **Event**  
gastrointestinal disorder

**Reports**  
8

**Reporting signal score**

12.6245
- **Event**  
gastrointestinal haemorrhage

**Reports**  
10

**Reporting signal score**

13.9821

And 49 more, listed on the interactive page.

### Trial references (307)

- NCT02721589  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02721589)
- NCT03171220  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03171220)
- NCT03182673  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03182673)
- NCT03871855  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03871855)
- NCT04282278  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04282278)
- NCT04346381  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04346381)
- NCT04832204  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04832204)
- NCT05214976  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05214976)
- NCT05429398  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05429398)
- NCT05605496  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05605496)
- NCT05699811  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05699811)
- NCT05799183  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05799183)
- NCT05809336  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05809336)
- NCT05941507  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05941507)
- NCT02738489  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02738489)
- NCT04331093  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04331093)
- NCT04593485  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04593485)
- NCT04979585  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04979585)
- NCT05051865  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05051865)
- NCT05512481  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05512481)
- NCT05789043  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05789043)
- NCT05983237  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05983237)
- NCT02742935  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02742935)
- NCT03394287  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03394287)
- NCT03945604  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03945604)

And 282 more, listed on the interactive page.

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (462)

- A Clinical Study of a Preoperative Translational Therapy for Unresectable Gallbladder Cancer
- A Clinical Study Of Camrelizumab With Or Without Radiotherapy In The Treatment Of Esophageal Cancer
- A Clinical Study of Chemoradiotherapy Sequential Fluzoparib in Pan-solid Tumors
- A Clinical Study of DEB-TACE Combined With Surufatinib and Camrelizumab in the Treatment of Inoperable or Metastatic ICC
- A Clinical Study of Exploring Camrelizumab in the Treatment of Colorectal Mucinous Adenocarcinoma(MAC)
- A Clinical Study of the Efficacy and Safety of Chidamide in Combination With Camrelizumab and Carboplatin or Capecitabine in the Second and Third Line Treatment of Relapsed/Metastatic Triple-negative Breast Cancer
- A Clinical Study To Evaluate Camrelizumab (SHR-1210) Plus Capecitabine and Oxaliplatin Followed by Sequential Treatment With Camrelizumab Plus Apatinib Mesylate in Advanced or Metastatic Gastric Cancer (GC) or Gastroesophageal Junction Cancer (GEJ) Without Prior Systemic Therapy
- A Multi-center, Randomized, Open-label, Phase III Study Comparing PD-1 Inhibitor Combined With Antivascular Therapy and Anthracycline/Taxane-based Adjuvant Chemotherapy Versus Anthracycline/Taxane-based Adjuvant Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer
- A Multicenter Phase II Clinical Study of Neoadjuvant Use of Camrelizumab in Combination With Chemotherapy for Organ Preservation in Esophageal Cancer
- A Multicenter, Randomized Controlled, Phase II Clinical Study of First-line Chemotherapy and Camrelizumab With or Without Radiotherapy in the Treatment of Oligometastatic Esophageal Cancer
- A Multicenter, Randomized, Open-label, Controlled Study of HAIC Combined With Camrelizumab and Apatinib Mesylate for Perioperative Treatment of Resectable Hepatocellular Carcinoma With High-risk Recurrence Factors
- A Neoadjuvant Hepatocellular Carcinoma Study of Camrelizumab in Combination With Apatinib and Oxaliplatin
- A Non-interventional Registration Study of Monotherapy or Combination Regimens Based on Camrelizumab or Famitinib for the Treatment of Cervical Cancer
- A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma
- A Phase II Exploratory Clinical Trial of Multiple Drug Combinations in the Treatment of Advanced Esophageal Squamous Cell Carcinoma
- A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC
- A Phase II Trial of Camrelizumab Combined With Famitinib for Adjuvant Treatment of Stage II-IIIA NSCLC.
- A Phase II Trial of Camrelizumab in Combination With Apatinib and Eribulin in Patients With Advanced TNBC
- A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients
- A Phase II/III Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Nasopharyngeal Carcinoma

### In development for (105)

- Acral lentiginous melanoma Phase 2
- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 2
- [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) Phase 2
- Adrenal cortex carcinoma Phase 2
- Alveolar soft part sarcoma Phase 2
- [Biliary tract cancer](https://trialight.com/data/condition/biliary-tract-cancer-6b9535c9-ccaa-5b47-8c46-0d05d39d7c62.md) Phase 2
- Bone sarcoma Phase 2
- [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 3
- [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 3
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 2
- Carcinoma of esophagus Phase 3
- [Carcinosarcoma](https://trialight.com/data/condition/carcinosarcoma-c51dcec3-1436-5748-baf0-015919f3ca55.md) Phase 2
- Cervical adenocarcinoma Phase 2
- Cervical adenosquamous carcinoma Phase 2
- [Cervical cancer](https://trialight.com/data/condition/cervical-cancer-10fb8f6c-5aac-5281-8f06-7238adeec443.md) Phase 2
- [Cervical carcinoma](https://trialight.com/data/condition/cervical-carcinoma-fe520bb0-bc93-5cf1-a9ee-5a3ce33f2fdd.md) Phase 2
- Cervical squamous cell carcinoma Phase 2
- [Cholangiocarcinoma](https://trialight.com/data/condition/cholangiocarcinoma-3777afe4-5189-5eb1-82f8-0c3446cb902f.md) Phase 2
- Chordoma Phase 2
- Classic Hodgkin lymphoma Phase 3

### Other linked conditions (3)

- Malignant epithelial tumor of ovary
- [Ovarian carcinoma](https://trialight.com/data/condition/ovarian-carcinoma-e5ec8fdc-01ec-5cd9-9507-107d23d3a30b.md)
- Ovarian clear cell cancer

### Targets (1)

- [PDCD1](https://trialight.com/data/target/pdcd1-a7b9a076-9fdd-55c9-9ce8-e558e5c7503f.md) Programmed cell death protein 1 antagonist

---

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