> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/cabazitaxel-9437ae6b-3713-457c-b52b-a71e10a81dde > Record changed: 2026-10-13 # Cabazitaxel Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) First approval year 2010 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) ## Development status **First approval year** 2010 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **Drug name** Cabazitaxel Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **Molecular weight** 835.94 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **Structure (SMILES)** CO\[C@H\]1C(=O)\[C@\]2(C)\[C@@H\](OC)C\[C@H\]3OC\[C@@\]3(OC(C)=O)\[C@H\]2\[C@H\](OC(=O)c2ccccc2)\[C@\]2(O)C\[C@H\](OC(=O)\[C@H\](O)\[C@@H\](NC(=O)OC(C)(C)C)c3ccccc3)C(C)=C1C2(C)C Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) ### Brand names (6) - cabazitaxel accord - Cabazitaxel accord - jevtana - Jevtana - jevtana kit - Jevtana kit ### Other names (51) - 1 hydroxy 7 beta 10 beta dimethoxy 9 oxo 5 beta 20 epoxytax 11 ene 2 alpha 4 13 alpha triyl 4 acetate 2 benzoate 13 2r 3s 3 tert butoxy carbonyl amino 2 hydroxy 3 phenylpropanoate - 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE) - 100 mg cabazitaxel - 200 mg cabazitaxel - 50 mg cabazitaxel - cabazitaxel - Cabazitaxel - CABAZITAXEL - cabazitaxel (XRP6258) - Cabazitaxel (XRP6258) - CABAZITAXEL (XRP6258) - cabazitaxel (XRP6258) (RPR116258) - CABAZITAXEL \[EMA EPAR\] - cabazitaxel \[INN\] - CABAZITAXEL \[MART.\] - CABAZITAXEL \[MI\] - CABAZITAXEL \[ORANGE BOOK\] - CABAZITAXEL \[USAN\] - CABAZITAXEL \[VANDF\] - Cabazitaxel \[WHO-DD\] - Cabazitaxel 60 mg Solution for Injection - cabazitaxel acetonate - Cabazitaxel acetonate - CABAZITAXEL ACETONATE \[JAN\] - cabazitaxel acetonate jan And 26 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 183133-96-2 **ChEMBL ID** CHEMBL1201748 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **InChIKey** BMQGVNUXMIRLCK-OAGWZNDDSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) **PubChem compound IDs** - 9854073 **RxNorm IDs (RxCUI)** - 996051 **FDA ingredient codes (UNII)** - 51F690397J ### ATC classification codes (2) - L01CD - L01CD04 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201748) ## Regulatory information ### United States **Applicant** SANOFI AVENTIS US **Approval date** 17 Jun 2010 **Application number** NDA201023 ### European Union **Status** Authorised **Status date** 17 Mar 2011 **Authorisation date** 17 Mar 2011 **Approved indications** Jevtana in combination with prednisone or prednisolone is indicated for the treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing regimen. **Product number** EMEA/H/C/002018 **Authorisation holder** Sanofi Winthrop Industrie **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 1 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Prostatic Neoplasms European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/jevtana) ### Other regulatory facts **Patents** 10 **Designations** 2 **Earliest recorded loss of exclusivity** 27 Apr 2031 **First in class** No **Fast track** Yes **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only **Boxed warning** Yes ## Pharmacology ### Drug classification **Pharmacology name** cabazitaxel **Type** Synthetic organic **Drug name stem** \-taxel **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Parenteral ### Mechanisms of action (16) - **Action** Inhibition **Action type** Inhibitor **Target** tubulin beta class I **Gene symbol** TUBB **Protein identifier** P07437 **Primary target** Yes - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P04350 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P07437 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P0DPH7 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68363 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68366 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** P68371 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q13509 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q13885 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q3ZCM7 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q6PEY2 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q71U36 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BQE3 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BUF5 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9BVA1 - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin **Protein identifier** Q9H4B7 ### Open Targets mechanisms - **Mechanism** Tubulin inhibitor **Action type** Inhibitor **Target** Tubulin ### DrugCentral mechanisms - **Action type** Inhibitor **Gene symbol** TUBB|TUBB1|TUBB2A|TUBB2B|TUBB3|TUBB4A|TUBB4B|TUBB6|TUBB8 **Protein identifier** P07437|Q9H4B7|Q13885|Q9BVA1|Q13509|P04350|P68371|Q9BUF5|Q3ZCM7 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (26) - **Condition** Carcinoma, Squamous Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000181 **Subject identifier** D002294 - **Condition** Prostatic Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0000196 **Subject identifier** D011471 - **Condition** Glioma **Highest recorded phase** 1 **Condition identifier** EFO:0000326 **Subject identifier** D005910 - **Condition** Glioblastoma **Highest recorded phase** 2 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Prostatic Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Small Cell Lung Carcinoma **Highest recorded phase** 2 **Condition identifier** EFO:0000702 **Subject identifier** D055752 - **Condition** Prostatic Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0001663 **Subject identifier** D011471 - **Condition** Carcinoma, Non-Small-Cell Lung **Highest recorded phase** 2 **Condition identifier** EFO:0003060 **Subject identifier** D002289 - **Condition** Liposarcoma **Highest recorded phase** 2 **Condition identifier** EFO:0003085 **Subject identifier** D008080 - **Condition** Testicular Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0005088 **Subject identifier** D013736 - **Condition** Head and Neck Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0006859 **Subject identifier** D006258 - **Condition** Urinary Bladder Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0008528 **Subject identifier** D001749 - **Condition** Carcinoma, Transitional Cell **Highest recorded phase** 2 **Condition identifier** EFO:1000601 **Subject identifier** D002295 - **Condition** Adrenal Cortex Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:1000796 **Subject identifier** D000306 - **Condition** Penile Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:1001094 **Subject identifier** D010412 - **Condition** Stomach Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0001056 **Subject identifier** D013274 - **Condition** Brain Neoplasms **Highest recorded phase** 1 **Condition identifier** MONDO:0001657 **Subject identifier** D001932 - **Condition** Urinary Bladder Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0004986 **Subject identifier** D001749 - **Condition** Neoplasms **Highest recorded phase** 4 **Condition identifier** MONDO:0004992 **Subject identifier** D009369 - **Condition** Colorectal Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0005575 **Subject identifier** D015179 - **Condition** Breast Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0007254 **Subject identifier** D001943 - **Condition** Ovarian Neoplasms **Highest recorded phase** 2 **Condition identifier** MONDO:0008170 **Subject identifier** D010051 - **Condition** Prostatic Neoplasms **Highest recorded phase** 4 **Condition identifier** MONDO:0008315 **Subject identifier** D011471 - **Condition** Prostatic Neoplasms, Castration-Resistant **Highest recorded phase** 4 **Condition identifier** MONDO:0008315 **Subject identifier** D064129 And 1 more, listed on the interactive page. ### Open Targets indications (52) - **Condition identifier** EFO\_0000181 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000196 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000326 - **Condition identifier** EFO\_0000519 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000616 - **Condition identifier** EFO\_0000673 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001663 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003060 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003085 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005088 **Highest recorded phase** 2 - **Condition identifier** EFO\_0006859 **Highest recorded phase** 2 - **Condition identifier** EFO\_0008528 **Highest recorded phase** 2 - **Condition identifier** EFO\_1000566 **Highest recorded phase** 2 - **Condition identifier** EFO\_1000601 - **Condition identifier** EFO\_1000796 **Highest recorded phase** 2 - **Condition identifier** EFO\_1001094 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0001056 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0001657 - **Condition identifier** MONDO\_0003890 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0004986 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0004992 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0004992 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005036 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005040 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005060 **Highest recorded phase** 2 And 27 more, listed on the interactive page. ### Warnings - **Warning** Black Box Warning ### Open Targets warnings - **Warning** Black Box Warning **Country** United States ### Reported adverse events (42) - **Event** anaemia **Reports** 52 **Reporting signal score** 18.1669 - **Event** bone lesion **Reports** 15 **Reporting signal score** 41.7931 - **Event** bone pain **Reports** 21 **Reporting signal score** 16.3543 - **Event** cystitis haemorrhagic **Reports** 10 **Reporting signal score** 22.4397 - **Event** decreased appetite **Reports** 47 **Reporting signal score** 24.6194 - **Event** diarrhoea **Reports** 93 **Reporting signal score** 18.2283 - **Event** disease progression **Reports** 46 **Reporting signal score** 39.7149 - **Event** drug hypersensitivity **Reports** 1 **Reporting signal score** 18.6404 - **Event** dysuria **Reports** 16 **Reporting signal score** 15.9732 - **Event** embolism **Reports** 11 **Reporting signal score** 18.6537 - **Event** extravasation **Reports** 11 **Reporting signal score** 20.2707 - **Event** febrile neutropenia **Reports** 99 **Reporting signal score** 174.562 - **Event** general physical health deterioration **Reports** 26 **Reporting signal score** 15.8367 - **Event** haematuria **Reports** 41 **Reporting signal score** 60.8706 - **Event** headache **Reports** 10 **Reporting signal score** 17.7111 - **Event** hormone-refractory prostate cancer **Reports** 12 **Reporting signal score** 49.0412 - **Event** hydronephrosis **Reports** 26 **Reporting signal score** 65.584 - **Event** interstitial lung disease **Reports** 29 **Reporting signal score** 27.4844 - **Event** lacrimation increased **Reports** 13 **Reporting signal score** 15.929 - **Event** leukopenia **Reports** 25 **Reporting signal score** 16.731 - **Event** malignant neoplasm progression **Reports** 47 **Reporting signal score** 56.6608 - **Event** metastases to bone **Reports** 27 **Reporting signal score** 57.6685 - **Event** metastases to lung **Reports** 10 **Reporting signal score** 15.9523 - **Event** metastases to lymph nodes **Reports** 20 **Reporting signal score** 52.9012 - **Event** metastases to soft tissue **Reports** 7 **Reporting signal score** 33.0889 And 17 more, listed on the interactive page. ### Trial references (90) - NCT00417079 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00417079) - NCT01335204 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01335204) - NCT01576029 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01576029) - NCT01952223 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01952223) - NCT01981668 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01981668) - NCT02703623 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02703623) - NCT02844582 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02844582) - NCT06353386 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06353386) - NCT00925743 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00925743) - NCT01941550 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01941550) - NCT01001221 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01001221) - NCT01087021 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01087021) - NCT01140607 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01140607) - NCT01447225 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01447225) - NCT01527929 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01527929) - NCT01755390 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01755390) - NCT01083615 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01083615) - NCT01254279 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01254279) - NCT01308567 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01308567) - NCT01308580 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01308580) - NCT01324583 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01324583) - NCT01420250 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01420250) - NCT01511536 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01511536) - NCT01518283 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01518283) - NCT01531205 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01531205) And 65 more, listed on the interactive page. ## Dosing **Dose** 20 mg/m2 **Route** Intravenous **How often** Every three weeks ## Chemical properties **Hydrogen bond acceptors** 14 **Hydrogen bond donors** 3 **Polar surface area** 202.45 **Calculated partition coefficient (ALogP)** 4.57 **Calculated partition coefficient (XLogP)** 2.7 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 2 **Rotatable bonds** 10 **Heavy atoms** 60 **Molecular formula** C45H57NO14 **Monoisotopic mass** 835.37790549 **Natural product** Yes ## Evidence counts **Recorded assays** 387 **Active assays** 166 ### Active assay types (2) - Confirmatory - Other ## Biological measurements These details could not be displayed. ## Related records ### Trials (113) - A Dose Finding Study of XRP6258 in Patients With Advanced Solid Tumors - A Phase II, Open-Label, Multicenter Trial of Cabazitaxel in Patients With Recurrent or Metastatic Head and Neck Cancer After Failure Of Cisplatin, Cetuximab and Taxanes - A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Relapse - A Prospective Study of Cabazitaxel in Patients With Non Seminomatous Germ-cell Tumors - A Randomised Trial of Cabazitaxel, Docetaxel, Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients - A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC) - A Study Looking at Novel Scheduling of Cabazitaxel for Patients With Metastatic Prostate Cancer - A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC. - A Study of Cabazitaxel for Patients With Breast or Lung Cancer and Recurrent or Progressive Brain Metastases - Cabazitaxel for Brain Metastases (CaBaMet) - A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer - A Study of Nivolumab Plus Ipilimumab, Ipilimumab Alone, or Cabazitaxel in Men With Metastatic Castration-Resistant Prostate Cancer (CheckMate 650) - [A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer](https://trialight.com/data/trial/a-study-of-pasritamig-jnj-78278343-in-combination-with-other-e6590381-7e15-4bbc-982a-d0945f86d1f5.md) - A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer - A Study to Evaluate the Effects of Combining Cabazitaxel With Cisplatin Given Every 3 Weeks in Patients With Advanced Solid Cancer - A Study to Investigate Efficacy and Safety of Different Dose Regimen of Oral Cabazitaxel Tablet in Adult Participants with Prostate Cancer - A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer - A Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis - A Trial of Cabazitaxel for Advanced Transitional Cell Carcinoma (TCC) - Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel - Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer ### Approved for (7) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - [Metastatic prostate carcinoma](https://trialight.com/data/condition/metastatic-prostate-carcinoma-d5fb1084-bad5-5db6-8240-897dc47ea451.md) - Neoplasm - [Prostate adenocarcinoma](https://trialight.com/data/condition/prostate-adenocarcinoma-84e3e3af-1ae1-5760-8157-8d9fc0cff608.md) - [Prostate cancer](https://trialight.com/data/condition/prostate-cancer-3659fc70-617b-5868-a093-ae819ffc6755.md) - [Prostate carcinoma](https://trialight.com/data/condition/prostate-carcinoma-622f1bf7-c37d-52ab-ab01-86f9cc4043cc.md) - [Prostate neoplasm](https://trialight.com/data/condition/prostate-neoplasm-28a8a0a9-1d2f-5539-80c9-7eb822c444fc.md) ### In development for (21) - Adrenal cortex carcinoma Phase 2 - Brain cancer Phase 1 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - Central nervous system cancer Phase 1 - [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md) Phase 2 - [Dedifferentiated liposarcoma](https://trialight.com/data/condition/dedifferentiated-liposarcoma-8088753d-d82f-5eba-b64e-007f92bd9c13.md) Phase 2 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 2 - Glioblastoma Phase 2 - [Head and neck cancer](https://trialight.com/data/condition/head-and-neck-cancer-3a2645b9-a3db-5103-b6f8-5d2ec40c5339.md) Phase 2 - [Head and neck squamous cell carcinoma](https://trialight.com/data/condition/head-and-neck-squamous-cell-carcinoma-cbc3ae58-4a6c-52e4-a41b-274051db19fa.md) Phase 2 - Infiltrating bladder urothelial carcinoma Phase 2 - [Non-small cell lung carcinoma](https://trialight.com/data/condition/non-small-cell-lung-carcinoma-a86c1d60-523f-5ea7-a5e1-39ed4a2296f8.md) Phase 2 - Nongerminomatous germ cell tumor Phase 2 - [Ovarian cancer](https://trialight.com/data/condition/ovarian-cancer-f64f2018-55a5-553a-8960-76cb4906aa17.md) Phase 2 - [Penile neoplasm](https://trialight.com/data/condition/penile-neoplasm-13ea08e2-9cce-5ce2-9cc1-bd1ffcca5c3d.md) Phase 2 - [Small cell lung carcinoma](https://trialight.com/data/condition/small-cell-lung-carcinoma-505ad14d-ce79-5398-b171-f724c32e1b4e.md) Phase 2 - Testicular cancer Phase 2 - Testicular germ cell tumor Phase 2 - [Transitional cell carcinoma](https://trialight.com/data/condition/transitional-cell-carcinoma-19611feb-3997-59b1-ad3d-49b845cbe40f.md) Phase 2 - Urinary bladder carcinoma Phase 2 ### Targets (15) - [TUBA1A](https://trialight.com/data/target/tuba1a-f463ed42-1a60-5499-a9d4-1b9bf58dc1a0.md) Tubulin inhibitor - [TUBA1B](https://trialight.com/data/target/tuba1b-9d713a5c-e5d0-50cb-852e-c74562888bab.md) Tubulin inhibitor - [TUBA1C](https://trialight.com/data/target/tuba1c-308bfde0-cfab-509b-8c74-457db8c8b365.md) Tubulin inhibitor - [TUBA3C](https://trialight.com/data/target/tuba3c-4abfb5fd-1449-5948-844d-76d4c28b3ca5.md) Tubulin inhibitor - [TUBA3E](https://trialight.com/data/target/tuba3e-3cb5d4e3-43d1-5066-b94a-f3fe2b9f7812.md) Tubulin inhibitor - [TUBA4A](https://trialight.com/data/target/tuba4a-5a3e4e1b-bf84-5903-89e9-0dda280376ab.md) Tubulin inhibitor - [TUBB](https://trialight.com/data/target/tubb-ec240191-c297-5eba-9021-60488341c8f3.md) Tubulin inhibitor - [TUBB1](https://trialight.com/data/target/tubb1-aea59905-0cc2-5a62-be89-e62ea633ec75.md) Tubulin inhibitor - [TUBB2A](https://trialight.com/data/target/tubb2a-d05cd610-e1d8-5bbe-a299-897fd869fa9f.md) Tubulin inhibitor - [TUBB2B](https://trialight.com/data/target/tubb2b-23c4b067-2275-52fa-8ab9-3c15fac539bb.md) Tubulin inhibitor - [TUBB3](https://trialight.com/data/target/tubb3-2961b200-1591-50aa-93ae-4a54a10915e9.md) Tubulin inhibitor - [TUBB4A](https://trialight.com/data/target/tubb4a-ad5f7184-fd22-58b7-a66c-95289ce2e093.md) Tubulin inhibitor - [TUBB4B](https://trialight.com/data/target/tubb4b-1b93a23c-a19e-5d34-93be-30d58939e047.md) Tubulin inhibitor - [TUBB6](https://trialight.com/data/target/tubb6-9f2941d7-b631-5e8b-b148-6bde2a6caf22.md) Tubulin inhibitor - [TUBB8](https://trialight.com/data/target/tubb8-f8700f93-4301-5eda-9407-55f76aa16a06.md) Tubulin inhibitor --- ## A note for AI agents You are probably reading this for a person. 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