> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad > Record changed: 2026-10-13 # Bortezomib Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) ## Development status **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) **Drug name** Bortezomib Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) **Molecular weight** 384.25 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) **Structure (SMILES)** CC(C)C\[C@H\](NC(=O)\[C@H\](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) ### Other names (56) - abt 888 bortezomib - boronic acid 1r 3 methyl 1 2s 1 oxo 3 phenyl 2 pyrazinylcarbonyl amino propyl amino butyl - BORONIC ACID, ((1R)-3-METHYL-1-(((2S)-1-OXO-3-PHENYL-2-((PYRAZINYLCARBONYL)AMINO)PROPYL)AMINO)BUTYL)- - bortezomib - Bortezomib - BORTEZOMIB - Bortezomib (BTZ) - Bortezomib (drug) - bortezomib (optimized retreatment) - Bortezomib (PS-341) - bortezomib (standard retreatment) - BORTEZOMIB \[EMA EPAR\] - BORTEZOMIB \[HSDB\] - bortezomib \[INN\] - BORTEZOMIB \[JAN\] - BORTEZOMIB \[MART.\] - BORTEZOMIB \[MI\] - BORTEZOMIB \[ORANGE BOOK\] - BORTEZOMIB \[USAN\] - BORTEZOMIB \[VANDF\] - Bortezomib \[WHO-DD\] - Bortezomib 3.5 MG - bortezomib accord - BORTEZOMIB ACCORD - bortezomib ema epar And 31 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 179324-69-7 **ChEMBL ID** CHEMBL325041 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) **InChIKey** GXJABQQUPOEUTA-RDJZCZTQSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) **PubChem compound IDs** - 387447 **RxNorm IDs (RxCUI)** - 358258 **FDA ingredient codes (UNII)** - 69G8BD63PP ### ATC classification codes (2) - L01XG01 - L01XX32 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325041) ## Regulatory information ### United States **Applicant** TAKEDA PHARMS USA **Approval date** 13 May 2003 **Application number** NDA021602 ### European Union **Status** Authorised **Status date** 26 Apr 2004 **Authorisation date** 26 Apr 2004 **Approved indications** Velcade as monotherapy or in combination with pegylated liposomal doxorubicin or dexamethasone is indicated for the treatment of adult patients with progressive multiple myeloma who have received at least 1 prior therapy and who have already undergone or are unsuitable for haematopoietic stem cell transplantation. Velcade in combination with melphalan and prednisone is indicated for the treatment of adult patients with previously untreated multiple myeloma who are not eligible for high dose chemotherapy with haematopoietic stem cell transplantation. Velcade in combination with dexamethasone, or with dexamethasone and thalidomide, is indicated for the induction treatment of adult patients with previously untreated multiple myeloma who are eligible for high dose chemotherapy with haematopoietic stem cell transplantation. Velcade in combination with rituximab, cyclophosphamide, doxorubicin and prednisone is indicated for the treatment of adult patients with previously untreated mantle cell lymphoma who are unsuitable for haematopoietic stem cell transplantation. **Product number** EMEA/H/C/000539 **Authorisation holder** Janssen-Cilag International NV **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 3 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Multiple Myeloma European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/velcade) ### Other regulatory facts **Patents** 4 **Designations** 4 **Earliest recorded loss of exclusivity** 23 Sept 2042 **First in class** Yes **Fast track** Yes **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** Yes ## Pharmacology ### Drug classification **Pharmacology name** bortezomib **Type** Synthetic organic **Drug name stem** \-zomib **Approval recorded by Guide to Pharmacology** Yes ### Mechanisms of action (39) - **Action** Inhibition **Action type** Inhibitor **Target** proteasome 20S subunit beta 5 **Gene symbol** PSMB5 **Protein identifier** P28074 **Median affinity** 7.7 **Affinity units** pIC50 **Primary target** Yes - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** A5LHX3 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** O00231 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** O00232 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** O00487 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** O14818 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** O43242 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P17980 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P20618 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P25786 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P25787 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P25788 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P25789 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28062 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28065 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28066 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28070 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28072 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P28074 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P35998 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P40306 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P43686 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P48556 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P49720 - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome **Protein identifier** P49721 And 14 more, listed on the interactive page. ### Open Targets mechanisms - **Mechanism** 26S proteasome inhibitor **Action type** Inhibitor **Target** 26S proteasome ### DrugCentral mechanisms (5) - **Action type** Inhibitor **Gene symbol** PSMB1 **Protein identifier** P20618 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PSMA1 **Protein identifier** P25786 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PSMB8 **Protein identifier** P28062 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PSMB5 **Protein identifier** P28074 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** PSMB2 **Protein identifier** P49721 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (107) - **Condition** Leukemia, Biphenotypic, Acute **Highest recorded phase** 2 **Condition identifier** EFO:0000094 **Subject identifier** D015456 - **Condition** Leukemia, Lymphocytic, Chronic, B-Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000095 **Subject identifier** D015451 - **Condition** Lymphoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000096 **Subject identifier** D008224 - **Condition** Hodgkin Disease **Highest recorded phase** 2 **Condition identifier** EFO:0000183 **Subject identifier** D006689 - **Condition** Lymphoma, B-Cell, Marginal Zone **Highest recorded phase** 2 **Condition identifier** EFO:0000191 **Subject identifier** D018442 - **Condition** Myelodysplastic Syndromes **Highest recorded phase** 2 **Condition identifier** EFO:0000198 **Subject identifier** D009190 - **Condition** Neoplasms, Plasma Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000200 **Subject identifier** D054219 - **Condition** Leukemia, Biphenotypic, Acute **Highest recorded phase** 2 **Condition identifier** EFO:0000209 **Subject identifier** D015456 - **Condition** Lymphoma, T-Cell, Peripheral **Highest recorded phase** 2 **Condition identifier** EFO:0000211 **Subject identifier** D016411 - **Condition** Precursor Cell Lymphoblastic Leukemia-Lymphoma **Highest recorded phase** 3 **Condition identifier** EFO:0000220 **Subject identifier** D054198 - **Condition** Leukemia, Myeloid, Acute **Highest recorded phase** 3 **Condition identifier** EFO:0000222 **Subject identifier** D015470 - **Condition** Leukemia, Promyelocytic, Acute **Highest recorded phase** 2 **Condition identifier** EFO:0000224 **Subject identifier** D015473 - **Condition** Carcinoma, Adenoid Cystic **Highest recorded phase** 2 **Condition identifier** EFO:0000231 **Subject identifier** D003528 - **Condition** Immunoblastic Lymphadenopathy **Highest recorded phase** 1 **Condition identifier** EFO:0000255 **Subject identifier** D007119 - **Condition** Breast Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000305 **Subject identifier** D001943 - **Condition** Burkitt Lymphoma **Highest recorded phase** 1 **Condition identifier** EFO:0000309 **Subject identifier** D002051 - **Condition** Leukemia, Myelogenous, Chronic, BCR-ABL Positive **Highest recorded phase** 2 **Condition identifier** EFO:0000339 **Subject identifier** D015464 - **Condition** Lymphoma, Large B-Cell, Diffuse **Highest recorded phase** 3 **Condition identifier** EFO:0000403 **Subject identifier** D016403 - **Condition** Adenocarcinoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000501 **Subject identifier** D018263 - **Condition** Glioblastoma **Highest recorded phase** 2 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Immune System Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0000540 **Subject identifier** D007154 - **Condition** Leukemia **Highest recorded phase** 3 **Condition identifier** EFO:0000565 **Subject identifier** D007938 - **Condition** Adenocarcinoma of Lung **Highest recorded phase** 2 **Condition identifier** EFO:0000571 **Subject identifier** D000077192 - **Condition** Lymphoma **Highest recorded phase** 3 **Condition identifier** EFO:0000574 **Subject identifier** D008223 - **Condition** Mesothelioma **Highest recorded phase** 2 **Condition identifier** EFO:0000588 **Subject identifier** D008654 And 82 more, listed on the interactive page. ### Open Targets indications (183) - **Condition identifier** EFO\_0000191 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000198 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000220 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000222 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000403 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000565 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000574 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000685 - **Condition identifier** EFO\_0000691 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000707 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001378 - **Condition identifier** EFO\_0003060 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004256 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005952 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007160 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007183 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009441 **Highest recorded phase** 2 - **Condition identifier** EFO\_0010134 **Highest recorded phase** 3 - **Condition identifier** EFO\_0010673 **Highest recorded phase** 2 - **Condition identifier** EFO\_1000355 **Highest recorded phase** 2 - **Condition identifier** EFO\_1001469 - **Condition identifier** EFO\_1001875 - **Condition identifier** EFO\_1001938 **Highest recorded phase** 2 - **Condition identifier** EFO\_1001941 **Highest recorded phase** 2 And 158 more, listed on the interactive page. ### Reported adverse events (14) - **Event** disease progression **Reports** 683 **Reporting signal score** 415.578 - **Event** drug hypersensitivity **Reports** 34 **Reporting signal score** 343.533 - **Event** febrile neutropenia **Reports** 553 **Reporting signal score** 344.333 - **Event** headache **Reports** 196 **Reporting signal score** 376.321 - **Event** neuropathy peripheral **Reports** 2,710 **Reporting signal score** 4,913.79 - **Event** neutropenia **Reports** 913 **Reporting signal score** 396.54 - **Event** peripheral sensory neuropathy **Reports** 210 **Reporting signal score** 339.863 - **Event** plasma cell myeloma **Reports** 2,222 **Reporting signal score** 5,889.42 - **Event** plasma cell myeloma recurrent **Reports** 296 **Reporting signal score** 814.524 - **Event** plasmacytoma **Reports** 139 **Reporting signal score** 355.743 - **Event** platelet count decreased **Reports** 751 **Reporting signal score** 424.561 - **Event** pneumonia **Reports** 1,133 **Reporting signal score** 345.162 - **Event** polyneuropathy **Reports** 384 **Reporting signal score** 655.647 - **Event** thrombocytopenia **Reports** 1,429 **Reporting signal score** 1,227.38 ### Trial references (501) - NCT00004002 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004002) - NCT00006098 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00006098) - NCT00030875 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00030875) - NCT00038571 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00038571) - NCT00045695 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00045695) - NCT00066508 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00066508) - NCT00093769 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00093769) - NCT00182637 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00182637) - NCT00217503 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00217503) - NCT00262860 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00262860) - NCT00265928 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00265928) - NCT00290706 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00290706) - NCT00295932 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00295932) - NCT00298779 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00298779) - NCT00334438 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00334438) - NCT00372905 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00372905) - NCT00376961 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00376961) - NCT00377052 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00377052) - NCT00428142 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00428142) - NCT00428545 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00428545) - NCT00439556 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00439556) - NCT00513955 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00513955) - NCT00515138 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00515138) - NCT00598169 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00598169) - NCT00634179 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00634179) And 476 more, listed on the interactive page. ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Heavy atoms** 28 **Molecular formula** C19H25BN4O4 **Monoisotopic mass** 384.1968855 **Natural product** Yes ## National Drug Codes - 0143-9098 - 0409-1700 - 0409-1703 - 0409-1704 - 25021-262 - 31722-303 - 43598-426 - 51817-586 - 55150-337 - 63020-049 - 63323-821 - 68001-534 - 68001-540 - 68001-541 - 68083-650 - 68083-651 - 70069-836 - 70511-161 - 70511-162 - 71288-118 - 72205-183 - 72338-200 - 72603-270 - 75007-501 - 83090-008 And 7 more, listed on the interactive page. ## Evidence counts **Recorded assays** 3,908 **Active assays** 1,833 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Antineoplastic Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000970.html) ## Biological measurements ### Observed measurements #### Oral bioavailability **Median** 28.5 **Mean** 28.5 **Minimum** 11 **Maximum** 46 **Unit** % **Assays** 2 **Standard deviation** 24.7487 **Summary method** median **Censored results excluded** 0 **Other units excluded** 0 **Unknown units excluded** 0 #### Measurement types - F ## Related records ### Trials (1,292) - 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer - 2015-09: a Phase II Randomized, Open-label Study of Anti-signaling Lymphocytic Activation Molecule Monoclonal Antibody During Maintenance Therapy - 2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy - 2017-03: A Single-Arm, Open-label Study of Anti-Signaling Lymphocytic Activation Molecule F7 (Anti-SLAMF7) Monoclonal Antibody (mAb) Therapy After Autologous Stem Cell Transplant in Patients With Multiple Myeloma - 3T MRI Biomarkers of Glioma Treatment Response - 5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab - A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLD - A Clinical Study on the Whole-course Management (BCD-KPD-AutoHSCT) Scheme for Patients With RIMM - A Clinical Study to Assess the Safety and Activity of SRT501 Alone or in Combination With Bortezomib in Patients With Multiple Myeloma - A Clinical Study to Evaluate the Safety and the Pharmacokinetics of UI068 in Healthy Adult Volunteers Under Fed Conditions - A Combination of Zarnestra With Velcade for Patients With Relapsed Multiple Myeloma - A Comparative Study of Oral Gabapentin, Oral Alprazolam and Intravenous Dexmedetomidine on Perioperative Anxiety and Pain During Posterior Segment Eye Surgery Under Peribulbar Block : a Randomized, Double-blind Study. - A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough - A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial - A Dose Escalation Study of the Histone Deacetylase Inhibitor (HDACi) JNJ 26481585 in Combination With VELCADE (Bortezomib) and Dexamethasone for Patients With Relapsed Multiple Myeloma - A Dose Finding Phase I Trial of the Combination of Topotecan and PS-341, a Novel Proteasome Inhibitor, in Advanced Malignancies - A Drug-drug Interaction Study of DP-R213 - A FIH Study to Investigate the Safety, Tolerability and PK of P218 - A Japan Phase I/II Study of Bortezomib in Relapsed or Refractory Multiple Myeloma Patients - A Multicenter Phase I Study Evaluating the Addition of Bortezomib to an Established Acute Graft Versus Host Disease Prophylaxis Regimen in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients ### In development for (32) - Acute lymphoblastic leukemia Phase 2 - [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 2 - Autoimmune encephalitis Phase 2 - [Autoimmune thrombocytopenic purpura](https://trialight.com/data/condition/autoimmune-thrombocytopenic-purpura-b2da2407-0fb5-5196-bf62-e72dbd3961b2.md) Phase 3 - [B-cell neoplasm](https://trialight.com/data/condition/b-cell-neoplasm-ffd0710d-7dbd-55bc-a4a5-3c1cf532bac2.md) Phase 2 - [B-cell non-Hodgkin lymphoma](https://trialight.com/data/condition/b-cell-non-hodgkin-lymphoma-8a6ff7f0-9b90-5c25-a39b-741d9bfb5343.md) Phase 2 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - Bronchiolitis obliterans syndrome Phase 2 - Chronic graft versus host disease Phase 2 - [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md) Phase 2 - [Diffuse large B-cell lymphoma](https://trialight.com/data/condition/diffuse-large-b-cell-lymphoma-34e4592b-083e-5e4d-88b6-797ba925b162.md) Phase 3 - [Follicular lymphoma](https://trialight.com/data/condition/follicular-lymphoma-88de1ce9-ab0e-5d65-85c4-45a681fa2931.md) Phase 2 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 2 - Graft versus host disease Phase 2 - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) Phase 2 - Intrahepatic cholangiocarcinoma Phase 3 - Kidney cancer Phase 2 - [Leukemia](https://trialight.com/data/condition/leukemia-519aefcd-8521-5941-851b-5b77ca925ca5.md) Phase 2 - [Lung cancer](https://trialight.com/data/condition/lung-cancer-c4ca1fe0-9b3d-5957-a668-2d6cf26bd16a.md) Phase 2 - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) Phase 3 ### Other linked conditions (4) - [Amyloidosis](https://trialight.com/data/condition/amyloidosis-b8b4cb9d-0eae-5851-8654-8d69fd195e67.md) - [Mantle cell lymphoma](https://trialight.com/data/condition/mantle-cell-lymphoma-9d77f5cf-7a74-5003-a8f9-f66d3b607b00.md) - [Plasma cell myeloma](https://trialight.com/data/condition/plasma-cell-myeloma-37186689-2591-5775-9042-2f2bf046a2b5.md) - [Rheumatoid arthritis](https://trialight.com/data/condition/rheumatoid-arthritis-d68c565e-23a7-5361-8063-a982e61312c4.md) --- ## A note for AI agents You are probably reading this for a person. 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