> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/bordetella-pertussis-pertactin-autotransporter-0bc6f104-7b2d-406d-b6e5-8f08fbcee57d > Record changed: 2026-11-04 # Bordetella pertussis pertactin autotransporter Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) First approval year 1997 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) ## Development status **First approval year** 1997 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) **Drug name** Bordetella pertussis pertactin autotransporter Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) ### Brand names (10) - bordetella pertussis pertactin autotransporter component of infanrix hepb - Bordetella pertussis pertactin autotransporter component of infanrix hepb - bordetella pertussis pertactin autotransporter component of infanrix hexa - Bordetella pertussis pertactin autotransporter component of infanrix hexa - bordetella pertussis pertactin autotransporter component of infanrix penta - Bordetella pertussis pertactin autotransporter component of infanrix penta - bordetella pertussis pertactin autotransporter component of triacelluvax - Bordetella pertussis pertactin autotransporter component of triacelluvax - bordetella pertussis pertactin autotransporter component of vaxelis - Bordetella pertussis pertactin autotransporter component of vaxelis ### Other names (2) - bordetella pertussis pertactin autotransporter - Bordetella pertussis pertactin autotransporter ## Identifiers **ChEMBL ID** CHEMBL6068350 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068350) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Mechanisms of action - **Mechanism** Pertactin autotransporter vaccine antigen **Action type** VACCINE\_ANTIGEN **Target** Pertactin autotransporter **Protein identifier** P14283 ### Open Targets mechanisms - **Mechanism** Pertactin autotransporter vaccine antigen **Action type** VACCINE ANTIGEN **Target** Pertactin autotransporter ### Investigated indications (2) - **Condition** Whooping Cough **Highest recorded phase** 4 **Condition identifier** EFO:0000650 **Subject identifier** D014917 - **Condition** Vaccination **Highest recorded phase** 4 **Condition identifier** EFO:0004292 **Subject identifier** D014611 ### Open Targets indications (10) - **Condition identifier** EFO\_0000650 - **Condition identifier** EFO\_0004197 - **Condition identifier** EFO\_0005549 - **Condition identifier** EFO\_0005593 - **Condition identifier** EFO\_0007450 - **Condition identifier** MONDO\_0005077 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005344 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005504 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005526 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0017373 **Highest recorded phase** 4 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (149) - 3 Formulations of Hib-MenCY-TT Vaccine & 1 Formulation of Hib-MenC-TT Vaccine Compared to Licensed Meningococcal Serogroup C Conjugate Vaccine, Each Administered at 2,3,4 Mths of Age - [A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP)](https://trialight.com/data/trial/a-clinical-trial-of-diphtheria-tetanus-and-acellular-1a92f433-d4c5-49a1-86bf-1c85eae578f4.md) - [A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component)](https://trialight.com/data/trial/a-clinical-trials-of-adsorbed-cell-free-dpt-vaccine-five-dca16796-773d-4e86-acf1-c706700c4704.md) - A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) - [A Phase II Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents)](https://trialight.com/data/trial/a-phase-ii-clinical-trial-of-absorbed-acellular-pertussis-73cc426d-48a7-4776-a534-d6eded0b6880.md) - A Study of DTaP-IPV-Hep B-PRP-T Vaccine Given With Prevenar™ and Rotarix™ in Healthy Latin American Infants - A Study of DTaP//PRP-T Combined Vaccine (ACTACEL) Versus Local DTaP and Act-HIB Monovalent Vaccine in Healthy Infants - A Study of the Immunogenicity and Safety of Whole-Cell Pertussis Containing Vaccine Administered Concomitantly With RotaTeq™ (V260) or Rotarix™ (V260-036)(WITHDRAWN) - A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Healthy Japanese Adolescents Aged 11 Years to <13 Years - A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants - A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants - A Study to Assess the Safety of Adacel® Vaccine - A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults - A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers - A Study to Evaluate the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine in Healthy Non-pregnant Females From 9 to 49 Years of Age - A Study to Investigate Vaccine Responses in Subcutaneous Amlitelimab Treated Atopic Dermatitis Participants Aged 18 Years and Older Compared With Placebo - A Trial Comparing Two Pertussis-containing Vaccines in Pregnancy and Vaccine Responses in UK Mothers and Their Infants - Anti-Hep B Antibodies at Age 12 to 18 Months After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine Concomitantly With Prevnar® at 2, 4 and 6 Months of Age - Antibody Persistence at Age 3.5 and 4.5 Years After Primary and Booster DTaP-IPV-Hep B-PRP~T or Infanrix Hexa Vaccination - Assessment of Antibody Persistence in Children Previously Vaccinated With Pneumococcal Conjugate Vaccine ### Approved for (5) - [Diphtheria](https://trialight.com/data/condition/diphtheria-1a3815ca-3ad9-5b77-b86f-11d55e29e9fa.md) - [Hepatitis B virus infection](https://trialight.com/data/condition/hepatitis-b-virus-infection-63cb6d13-50c4-5e97-86fd-ce5481d9d1c6.md) - [Pertussis](https://trialight.com/data/condition/pertussis-810232d3-8d41-590a-8f38-1061f23d3a9f.md) - [Poliomyelitis](https://trialight.com/data/condition/poliomyelitis-5f8120f0-b67f-5e12-862f-914f03ab5ac7.md) - [Tetanus](https://trialight.com/data/condition/tetanus-a589c209-81c5-56e6-8a55-6d96fedb2c61.md) --- ## A note for AI agents You are probably reading this for a person. 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