> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/bofanglutide-35c869ee-ff48-4421-a0b9-f1eac8a5a180 > Record changed: 2026-10-13 # Bofanglutide Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) Drug type Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) ## Names and chemistry **Drug type** Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) **Drug name** Bofanglutide Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) ### Other names (19) - 7 37 glucagon like peptide 1 8 glycine 26 n6 22s 22 44 dicarboxy 1 10 19 24 tetraoxo 3 6 12 15 tetraoxa 9 18 23 triazatetratetracont 1 yl l lysine 34 arginine human - 7-37-Glucagon-like peptide 1 \[8-glycine,26-\[N6-\[(22S)-22,44-dicarboxy-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazatetratetracont-1-yl\]-L-lysine\],34-arginine\] (human) - bofanglutida - Bofanglutida - bofanglutide - Bofanglutide - bofanglutide \[INN\] - BOFANGLUTIDE \[USAN\] - Bofanglutide \[WHO-DD\] - bofanglutide inn - bofanglutide usan - bofanglutide who dd - glr1033 - GLR1033 - gzr18 - GZR18 - GZR18 injection - l histidylglycyl l α glutamylglycyl l threonyl l phenylalanyl lthreonyl l seryl l α aspartyl l valyl l seryl l seryl l tyrosyl l leucyl l α glutamylglycyl l glutaminyl l alanyl l alanyl n6 22s 22 44 dicarboxy 10 19 24 trioxo 3 6 12 15 tetraoxa 9 18 23 triazatetratetracontan 1 oyl l lysyl l α glutamyl l phenylalanyl lisoleucyl l alanyl l tryptophyl l leucyl l valyl l arginylglycyl larginylglycine - L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-Lthreonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-\[(22S)-22,44-dicarboxy-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazatetratetracontan-1-oyl\]-L-lysyl-L-α-glutamyl-L-phenylalanyl-Lisoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-Larginylglycine ## Identifiers **CAS registry numbers** - 2668298-70-0 **ChEMBL ID** CHEMBL6068096 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068096) **FDA ingredient codes (UNII)** - X9RLV48FDH ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-tide ### Open Targets indications (2) - **Condition identifier** HP\_0001513 **Highest recorded phase** 2 - **Condition identifier** HP\_0025502 **Highest recorded phase** 2 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ### Sequences - **Component** Sequence **Type** Protein **Sequence** HGEGTFTSDVSSYLEGQAAKEFIAWLVRGRG ## Related records ### Trials (25) - A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects - A Phase I Study of GZR18 Injection in Healthy Subjects - A Phase I Study of GZR18 Injection in Obese/Overweight Subjects - A Phase I Study to Evaluate the PK and PD Profiles of GZR102 Injection Versus GZR4 Injection and GZR18 Injection Given Separately in Chinese Adult Overweight Subjects - A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Obese/Overweight Subjects - [A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus](https://trialight.com/data/trial/a-phase-iii-clinical-study-to-evaluate-the-efficacy-and-c5e61e32-d062-48d1-a4bc-78915bcc3e3c.md) - A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Subjects With Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise - A Study of GZR18 Injection in Chinese Adult Patients With Type 2 Diabetes Mellitus (T2DM) - A Study of GZR18 Injection in Chinese Obese/Overweight Patients - [A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus](https://trialight.com/data/trial/a-study-of-gzr18-injection-in-chinese-patients-with-type-2-eb8667c6-cec4-47d7-863c-4b4ecc5ee7a0.md) - [A Study of GZR18 Injection in Obese/Overweight Patients](https://trialight.com/data/trial/a-study-of-gzr18-injection-in-obese-overweight-patients-5fd2c091-2cc2-43f2-8a1d-acf642b19855.md) - A Study of GZR18 Tablet in Chinese Healthy Subjects - A Study to Compare the Efficacy and Safety of GZR102 Injection and GZR18 Injection in Type 2 Diabetes Mellitus - BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes - BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity - Bioequivalence Study of GZR18 Injection Before and After CMC Change - [Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants](https://trialight.com/data/trial/efficacy-and-safety-of-gzr18-every-2-weeks-versus-1f8d5834-78cb-49de-94b1-935332ff7e7a.md) - Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy - Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Receiving Positive Airway Pressure (PAP) Therapy - Extension Study of the Phase 3 Clinical Study of GZR18 Injection for Weight Loss --- ## A note for AI agents You are probably reading this for a person. 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