> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f
> Record changed: 2026-10-13

# Azacitidine

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

First approval year

2004

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

## Development status

**First approval year**

2004

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**Drug name**

Azacitidine

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**Molecular weight**

244.21

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**Structure (SMILES)**

Nc1ncn(\[C@@H\]2O\[C@H\](CO)\[C@@H\](O)\[C@H\]2O)c(=O)n1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

### Brand names (16)

- azacitidine
- Azacitidine
- azacitidine accord
- Azacitidine accord
- azacitidine betapharm
- Azacitidine betapharm
- azacitidine celgene
- Azacitidine celgene
- azacitidine kabi
- Azacitidine kabi
- azacitidine mylan
- Azacitidine mylan
- onureg
- Onureg
- vidaza
- Vidaza

### Other names (78)

- 1 3 5 triazin 2 1h one 4 amino 1 beta d ribofuranosyl
- 1,3,5-TRIAZIN-2(1H)-ONE, 4-AMINO-1-.BETA.-D-RIBOFURANOSYL-
- 4 amino 1 beta d ribofuranosyl s triazin 2 1h one
- 4-AMINO-1-.BETA.-D-RIBOFURANOSYL-S-TRIAZIN-2(1H)-ONE
- 5 azacitidine
- 5-azacitidine
- 5-Azacitidine
- 5' Azacitidine
- azacitidina
- Azacitidina
- azacitidine
- Azacitidine
- Azacitidine (AZA)
- Azacitidine (AZC)
- Azacitidine (BAML-16-001-S12 Arm A)
- Azacitidine (BAML-16-001-S12 Arm B)
- Azacitidine (BAML-16-001-S16)
- Azacitidine (BAML-16-001-S17)
- Azacitidine (BAML-16-001-S18)
- Azacitidine (BAML-16-001-S2)
- Azacitidine (BAML-16-001-S24)
- Azacitidine (BAML-16-001-S3)
- Azacitidine (BAML-16-001-S4)
- Azacitidine (BAML-16-001-S9)
- Azacitidine (Monotherapy)

And 53 more, listed on the interactive page.

## Identifiers

**ATC classification codes**

- L01BC07

Sources for recorded values

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**CAS registry numbers**

- 320-67-2

**ChEMBL ID**

CHEMBL1489

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**InChIKey**

NMUSYJAQQFHJEW-KVTDHHQDSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1489)

**PubChem compound IDs**

- 9444

**RxNorm IDs (RxCUI)**

- 1251

**FDA ingredient codes (UNII)**

- M801H13NRU

## Regulatory information

### United States

**Applicant**

BRISTOL-MYERS

**Approval date**

19 May 2004

**Application number**

NDA050794

### European Union

**Status**

Authorised

**Status date**

17 Dec 2008

**Authorisation date**

17 Dec 2008

**Approved indications**

Vidaza is indicated for the treatment of adult patients who are not eligible for haematopoietic stem cell transplantation (HSCT) with: intermediate 2 and high-risk myelodysplastic syndromes (MDS) according to the International Prognostic Scoring System (IPSS), chronic myelomonocytic leukaemia (CMML) with 10 29 % marrow blasts without myeloproliferative disorder, acute myeloid leukaemia (AML) with 20 30 % blasts and multi-lineage dysplasia, according to World Health Organisation (WHO) classification. Vidaza is indicated for the treatment of adult patients aged 65 years or older who are not eligible for HSCT with AML with >30% marrow blasts according to the WHO classification.

**Product number**

EMEA/H/C/000978

**Authorisation holder**

Bristol-Myers Squibb Pharma EEIG

**Priority medicines scheme**

No

**Generic**

No

**Biosimilar**

No

**Generic medicines**

4

**Biosimilar medicines**

0

**Advanced therapy**

No

**Conditional approval**

No

**Additional monitoring**

No

**Accelerated assessment**

Yes

**Exceptional circumstances**

No

#### Therapeutic areas

- Leukemia, Myeloid, Acute
- Leukemia, Myelomonocytic, Chronic
- Myelodysplastic Syndromes

European medicines record

Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/vidaza)

### Other regulatory facts

**Patents**

3

**Designations**

5

**Earliest recorded loss of exclusivity**

3 Jun 2030

**First in class**

No

**Fast track**

Yes

**Breakthrough designation**

Yes

**Orphan designation**

No

**Priority review**

Yes

**Orphan exclusivity**

No

**Accelerated approval**

No

**Availability**

Prescription only

## Pharmacology

### Drug classification

**Pharmacology name**

azacitidine

**Type**

Synthetic organic

**Drug name stem**

\-tidine

**Approval recorded by Guide to Pharmacology**

Yes

#### Administration routes

- Oral
- Parenteral

### Mechanisms of action (4)

- **Mechanism**  
DNA (cytosine-5)-methyltransferase 1 inhibitor

**Action type**  
Inhibitor

**Target**  
DNA (cytosine-5)-methyltransferase 1

**Protein identifier**  
P26358
- **Mechanism**  
DNA (cytosine-5)-methyltransferase 3A inhibitor

**Action type**  
Inhibitor

**Target**  
DNA (cytosine-5)-methyltransferase 3A

**Protein identifier**  
Q9Y6K1
- **Mechanism**  
DNA inhibitor

**Action type**  
Inhibitor

**Target**  
DNA
- **Mechanism**  
RNA inhibitor

**Action type**  
Inhibitor

**Target**  
RNA

### Open Targets mechanisms (2)

- **Mechanism**  
DNA (cytosine-5)-methyltransferase 1 inhibitor

**Action type**  
Inhibitor

**Target**  
DNA (cytosine-5)-methyltransferase 1
- **Mechanism**  
DNA (cytosine-5)-methyltransferase 3A inhibitor

**Action type**  
Inhibitor

**Target**  
DNA (cytosine-5)-methyltransferase 3A

### DrugCentral mechanisms (2)

- **Action type**  
Inhibitor

**Gene symbol**  
DNMT1

**Protein identifier**  
P26358

**Organism**  
Homo sapiens

**Target development level**  
Clinical
- **Action type**  
Inhibitor

**Gene symbol**  
DNMT3A

**Protein identifier**  
Q9Y6K1

**Organism**  
Homo sapiens

**Target development level**  
Clinical

### Investigated indications (68)

- **Condition**  
Leukemia, Lymphocytic, Chronic, B-Cell

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000095

**Subject identifier**  
D015451
- **Condition**  
Carcinoma, Squamous Cell

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000181

**Subject identifier**  
D002294
- **Condition**  
Hodgkin Disease

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000183

**Subject identifier**  
D006689
- **Condition**  
Myelodysplastic Syndromes

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000198

**Subject identifier**  
D009190
- **Condition**  
Lymphoma, T-Cell, Peripheral

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000211

**Subject identifier**  
D016411
- **Condition**  
Precursor Cell Lymphoblastic Leukemia-Lymphoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000220

**Subject identifier**  
D054198
- **Condition**  
Leukemia, Monocytic, Acute

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000221

**Subject identifier**  
D007948
- **Condition**  
Leukemia, Myeloid, Acute

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000222

**Subject identifier**  
D015470
- **Condition**  
Immunoblastic Lymphadenopathy

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000255

**Subject identifier**  
D007119
- **Condition**  
Glioma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000326

**Subject identifier**  
D005910
- **Condition**  
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000339

**Subject identifier**  
D015464
- **Condition**  
Melanoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000389

**Subject identifier**  
D008545
- **Condition**  
Lymphoma, Large B-Cell, Diffuse

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000403

**Subject identifier**  
D016403
- **Condition**  
Leukemia

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000565

**Subject identifier**  
D007938
- **Condition**  
Liposarcoma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000569

**Subject identifier**  
D008080
- **Condition**  
Lymphoma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000574

**Subject identifier**  
D008223
- **Condition**  
Neoplasms

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369
- **Condition**  
Osteosarcoma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000637

**Subject identifier**  
D012516
- **Condition**  
Prostatic Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000673

**Subject identifier**  
D011471
- **Condition**  
Carcinoma, Renal Cell

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000681

**Subject identifier**  
D002292
- **Condition**  
Sarcoma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000691

**Subject identifier**  
D012509
- **Condition**  
Carcinoma, Squamous Cell

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000707

**Subject identifier**  
D002294
- **Condition**  
Multiple Myeloma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0001378

**Subject identifier**  
D009101
- **Condition**  
Hematologic Neoplasms

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0001642

**Subject identifier**  
D019337
- **Condition**  
Melanoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0002617

**Subject identifier**  
D008545

And 43 more, listed on the interactive page.

### Open Targets indications (149)

- **Condition identifier**  
EFO\_0000183

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000198
- **Condition identifier**  
EFO\_0000211

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000220

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000221
- **Condition identifier**  
EFO\_0000222
- **Condition identifier**  
EFO\_0000255

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000326

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0000330

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000339

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000389

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0000565

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000569

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0000574

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000616
- **Condition identifier**  
EFO\_0000681
- **Condition identifier**  
EFO\_0001378

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0002427

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0002618

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0003060

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0003811
- **Condition identifier**  
EFO\_0003833
- **Condition identifier**  
EFO\_0003869

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0004251

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0004252

**Highest recorded phase**  
2

And 124 more, listed on the interactive page.

### Reported adverse events (24)

- **Event**  
acute febrile neutrophilic dermatosis

**Reports**  
46

**Reporting signal score**

111.665
- **Event**  
acute myeloid leukaemia

**Reports**  
195

**Reporting signal score**

506.244
- **Event**  
acute myeloid leukaemia recurrent

**Reports**  
52

**Reporting signal score**

190.609
- **Event**  
anaemia

**Reports**  
392

**Reporting signal score**

216.27
- **Event**  
blast cell count increased

**Reports**  
43

**Reporting signal score**

145.822
- **Event**  
bronchopulmonary aspergillosis

**Reports**  
63

**Reporting signal score**

127.176
- **Event**  
cytopenia

**Reports**  
120

**Reporting signal score**

247.869
- **Event**  
differentiation syndrome

**Reports**  
28

**Reporting signal score**

95.4096
- **Event**  
drug hypersensitivity

**Reports**  
11

**Reporting signal score**

89.8764
- **Event**  
febrile neutropenia

**Reports**  
1,034

**Reporting signal score**  
2,465.83
- **Event**  
headache

**Reports**  
46

**Reporting signal score**

115.254
- **Event**  
myelodysplastic syndrome

**Reports**  
111

**Reporting signal score**

195.043
- **Event**  
myelosuppression

**Reports**  
83

**Reporting signal score**

130.429
- **Event**  
neutropenia

**Reports**  
386

**Reporting signal score**

292.67
- **Event**  
neutrophil count decreased

**Reports**  
166

**Reporting signal score**

183.443
- **Event**  
pancytopenia

**Reports**  
226

**Reporting signal score**

247.616
- **Event**  
platelet count decreased

**Reports**  
259

**Reporting signal score**

192.028
- **Event**  
pneumonia

**Reports**  
416

**Reporting signal score**

207.446
- **Event**  
pneumonia fungal

**Reports**  
45

**Reporting signal score**

124.961
- **Event**  
pyrexia

**Reports**  
451

**Reporting signal score**

163.363
- **Event**  
sepsis

**Reports**  
250

**Reporting signal score**

254.79
- **Event**  
thrombocytopenia

**Reports**  
365

**Reporting signal score**

292.271
- **Event**  
transformation to acute myeloid leukaemia

**Reports**  
43

**Reporting signal score**

182.146
- **Event**  
white blood cell count decreased

**Reports**  
192

**Reporting signal score**

97.1438

### Trial references (409)

- NCT00004062  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004062)
- NCT00004871  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004871)
- NCT00005598  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00005598)
- NCT00071799  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00071799)
- NCT00102687  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00102687)
- NCT00118287  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00118287)
- NCT00326170  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00326170)
- NCT00339196  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00339196)
- NCT00379912  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00379912)
- NCT00382590  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00382590)
- NCT00384956  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00384956)
- NCT00439673  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00439673)
- NCT00446303  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00446303)
- NCT00495547  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00495547)
- NCT00569010  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00569010)
- NCT00666497  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00666497)
- NCT00704704  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00704704)
- NCT00721214  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00721214)
- NCT00741234  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00741234)
- NCT00761722  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00761722)
- NCT00795548  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00795548)
- NCT00887068  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00887068)
- NCT00897130  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00897130)
- NCT00915785  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00915785)
- NCT00923234  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00923234)

And 384 more, listed on the interactive page.

## Dosing

**Dose**

300 mg

**Route**

Oral

**How often**

Once daily on Days 1 through 14 of each 28-day cycle

### Conditions of use (5)

- Do not take 2 doses on the same day if a dose is vomited
- If a dose is missed, take as soon as possible on the same day, then resume normal schedule
- Swallow tablets whole, do not cut, crush, or chew
- Take doses at about the same time each day
- Take with or without food

## Chemical properties

**Hydrogen bond acceptors**

9

**Hydrogen bond donors**

4

**Polar surface area**

143.72

**Calculated partition coefficient (ALogP)**

\-3.17

**Calculated partition coefficient (XLogP)**

\-2.2

**Prodrug**

Yes

**Chirality**

Single enantiomer

**Inorganic**

No

**Rule-of-five violations**

0

**Rotatable bonds**

2

**Heavy atoms**

17

**Molecular formula**

C8H12N4O5

**Monoisotopic mass**

244.08076950

**Natural product**

Yes

## National Drug Codes

- 0143-9606
- 0781-3491
- 16714-927
- 16729-306
- 31722-365
- 43598-305
- 43598-465
- 43598-678
- 43817-906
- 55150-393
- 58458-002
- 59572-102
- 59572-730
- 59572-740
- 63323-771
- 68001-313
- 68001-527
- 68001-620
- 69539-112
- 70069-857
- 71288-115
- 71288-153
- 72485-201
- 72572-020
- 75907-225

And 3 more, listed on the interactive page.

## Evidence counts

**Recorded assays**

3,307

**Active assays**

470

### Active assay types (4)

- Confirmatory
- Other
- Screening
- Summary

## Pharmacologic actions

- Antimetabolites, Antineoplastic  
Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000964.html)
- Enzyme Inhibitors  
Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D004791.html)

## Biological measurements

### Observed measurements

#### Distribution coefficient (LogD)

**Median**

\-2.17

**Mean**

\-2.17

**Minimum**

\-2.17

**Maximum**

\-2.17

**Unit**

unitless

**Assays**

1

**Standard deviation**

0

**Summary method**

median

**Censored results excluded**

0

**Other units excluded**

0

**Unknown units excluded**

0

#### Measurement types

- LogD

## Related records

### Trials (700)

- 5 Day Versus 7 Day Azacitidine in Lower Risk Myelodysplastic Syndrome
- A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrome
- A Clinical Trial of Cidabenamine Plus Azacitidine to Prevent Post-Transplant Progression in High-Risk Peripheral T-Cell Lymphoma
- A Clinical Trial of Omacetaxine, Azacitidine, and Growth-Colony Stimulating Factor (G-CSF) for Myelodysplastic Syndromes (MDS)
- A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies
- A Clinical Trial of TQB3909 Tablets in Combination With Azacitidine for the Treatment of Myeloid Malignancies
- A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myeloma
- A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients
- A Dose-Finding and Efficacy Study of Venetoclax, CC-486, and Obinutuzumab in Follicular Lymphoma
- A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
- A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax
- A Multicenter Study on the Treatment of MDS/MPN Overlap Syndrome With AZA or Rux Combined With Selinexor
- A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction
- a New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia
- A Novel Conditioning Regimen for Myelodysplastic Syndrome With Moderate High IPSS-M Score
- A Phase 1 Protocol of 5-Azacytidine and Erlotinib in Advanced Solid Tumor Malignancies
- A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
- A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors
- A Phase 1 Study to Evaluate the Pharmacokinetics and Tolerability of Oral Azacitidine in Japanese Patients With Myelodysplastic Syndromes
- A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

### Approved for (6)

- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md)
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- [Chronic myelomonocytic leukemia](https://trialight.com/data/condition/chronic-myelomonocytic-leukemia-202fe88e-7b5d-5022-b6d2-095cac037e8e.md)
- [Myelodysplastic syndrome](https://trialight.com/data/condition/myelodysplastic-syndrome-f5df8ce5-6064-53d3-902c-f09fc4acd4bb.md)
- Myelodysplastic syndrome with excess blasts
- Neoplasm

### In development for (68)

- Acute erythroid leukemia Phase 2
- Acute kidney injury Phase 1
- Acute leukemia of ambiguous lineage Phase 1
- Acute lymphoblastic leukemia Phase 2
- Acute monocytic leukemia Phase 2
- [Angioimmunoblastic T-cell lymphoma](https://trialight.com/data/condition/angioimmunoblastic-t-cell-lymphoma-5b697108-b9cf-53e9-afde-71a36bf55d6b.md) Phase 3
- [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md) Phase 2
- Beta thalassemia Phase 2
- Beta-thalassemia major Phase 2
- Bone marrow neoplasm Phase 2
- [Brain neoplasm](https://trialight.com/data/condition/brain-neoplasm-b3dac71b-1d7b-5a65-8f64-89821506ad41.md) Early phase 1
- [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2
- [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 2
- CD4+/CD56+ hematodermic neoplasm Phase 1
- Central nervous system cancer Phase 1
- Childhood acute myeloid leukemia Phase 2
- Childhood ependymoma Phase 1
- Chronic myeloid leukemia Phase 1
- Classic Hodgkin lymphoma Phase 2
- [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md) Phase 1

### Other linked conditions (1)

- T-cell non-Hodgkin lymphoma

### Targets (2)

- [DNMT1](https://trialight.com/data/target/dnmt1-993c1dd6-907e-5847-b9a6-2bc7fd678568.md) DNA (cytosine-5)-methyltransferase 1 inhibitor
- [DNMT3A](https://trialight.com/data/target/dnmt3a-8a6f7e66-0b4a-50cc-a497-9e9823091168.md) DNA (cytosine-5)-methyltransferase 3A inhibitor

---

## A note for AI agents

You are probably reading this for a person. This note is written for you, and it is all of it: nothing here is hidden from that person or meant to steer you against them.

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