> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/aroxybutynin-777dd7fe-7007-406f-b4f5-210ed05e94c2
> Record changed: 2026-10-13

# Aroxybutynin

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

**Drug name**

Aroxybutynin

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

**Molecular weight**

357.49

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

**Structure (SMILES)**

CCN(CC)CC#CCOC(=O)\[C@\](O)(c1ccccc1)C1CCCCC1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

### Brand names (2)

- aroxybutynin component of ad 109
- Aroxybutynin component of ad-109

### Other names (18)

- (-)-oxybutynin
- (r)-oxybutynin
- ad 109 component aroxybutynin
- AD-109 component Aroxybutynin
- aroxybutynin
- Aroxybutynin
- aroxybutynin \[INN\]
- aroxybutynin inn
- aroxybutynina
- Aroxybutynina
- aroxybutynine
- Aroxybutynine
- oxybutynin
- oxybutynin r
- Oxybutynin, (-)-
- Oxybutynin, (r)-
- r oxybutynin
- R-oxybutynin

## Identifiers

**ATC classification codes**

- G04BD04

Sources for recorded values

Source: [mor.nlm.nih.gov](https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=32675)

**CAS registry numbers**

- 119618-21-2

**ChEMBL ID**

CHEMBL185434

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

**InChIKey**

XIQVNETUBQGFHX-QFIPXVFZSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL185434)

**PubChem compound IDs**

- 6098167

**RxNorm IDs (RxCUI)**

- 32675

**FDA ingredient codes (UNII)**

- 5BRQ29UUB7

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Open Targets indications (2)

- **Condition identifier**  
EFO\_0003918

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0007147

**Highest recorded phase**  
3

## Chemical properties

**Hydrogen bond acceptors**

4

**Hydrogen bond donors**

1

**Polar surface area**

49.77

**Calculated partition coefficient (ALogP)**

3.34

**Calculated partition coefficient (XLogP)**

4.2

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Rule-of-five violations**

0

**Rotatable bonds**

7

**Heavy atoms**

26

**Molecular formula**

C22H31NO3

**Monoisotopic mass**

357.23039385

**Natural product**

Yes

## Evidence counts

**Recorded assays**

3

**Active assays**

0

## Biological measurements

### Observed measurements

#### Cardiac potassium channel inhibition

**Median**

12,000

**Mean**

12,000

**Minimum**

12,000

**Maximum**

12,000

**Unit**

nM

**Assays**

1

**Standard deviation**

0

**Summary method**

median

**Censored results excluded**

0

**Other units excluded**

0

**Unknown units excluded**

0

#### Measurement types

- IC50

## Related records

### Trials (2)

- [Continuation Protocol for Obstructive Sleep Apnea (OSA)](https://trialight.com/data/trial/continuation-protocol-for-obstructive-sleep-apnea-osa-503f77c4-99a8-4bdd-8808-920cf3c086e7.md)
- Crossover Trial of AD109 in Obstructive Sleep Apnea

### In development for (1)

- [Obstructive sleep apnea syndrome](https://trialight.com/data/condition/obstructive-sleep-apnea-syndrome-02928491-a2d7-50f4-a4b7-30b79e6771ff.md) Phase 3

---

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