> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/aripiprazole-ca9997bd-e762-4bd5-ae57-3df4e68a30dd > Record changed: 2026-10-13 # Aripiprazole Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) First approval year 2002 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) ## Development status **First approval year** 2002 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **Drug name** Aripiprazole Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **Molecular weight** 448.39 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **Structure (SMILES)** O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) ### Brand names (22) - abilify - Abilify - abilify asimtufii - Abilify asimtufii - abilify maintena - Abilify maintena - abilify maintena kit - Abilify maintena kit - abilify mycite kit - Abilify mycite kit - aripiprazole - Aripiprazole - aripiprazole accord - Aripiprazole accord - Aripiprazole mylan pharma (previously aripiprazole pharmathen) - aripiprazole mylan pharma previously aripiprazole pharmathen - aripiprazole sandoz - Aripiprazole sandoz - aripiprazole zentiva - Aripiprazole zentiva - opipza - Opipza ### Other names (76) - 7 4 4 2 3 dichlorophenyl 1 piperazinyl butoxy 3 4 dihydrocarbostyril - 7-\[4-\[4-(2,3-Dichlorophenyl)-1-piperazinyl\]butoxy\]-3,4-dihydrocarbostyril - abilify - Abilify - Abilify (aripiprazole) - Abilify (Aripiprazole10 mg) - abilify maintena - Abilify maintena - Abilify Maintena - abilify mycite - Abilify mycite - ABILIFY MYCITE - Abilify MyCite® - Abilify prolonged release aqueous suspension for IM injection (Aripiprazole) - Abilify(aripiprazole) - Abilify(Aripiprazole) - Abilify® 10 mg tablet - Apipe (Aripiprazole10 mg) - aripiprazol - Aripiprazol - aripiprazole - Aripiprazole - aripiprazole (Abilify) - Aripiprazole (Abilify®) IM Depot Injection - Aripiprazole (BMS-337039) And 51 more, listed on the interactive page. ## Identifiers **ATC classification codes** - N05AX12 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **CAS registry numbers** - 129722-12-9 **ChEMBL ID** CHEMBL1112 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **InChIKey** CEUORZQYGODEFX-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1112) **PubChem compound IDs** - 60795 **RxNorm IDs (RxCUI)** - 89013 **FDA ingredient codes (UNII)** - 82VFR53I78 ## Regulatory information ### United States **Applicant** OTSUKA **Approval date** 15 Nov 2002 **Application number** NDA021436 ### European Union **Status** Authorised **Status date** 4 Jun 2004 **Authorisation date** 4 Jun 2004 **Approved indications** Abilify is indicated for the treatment of schizophrenia in adults and in adolescents aged 15 years and older. Abilify is indicated for the treatment of moderate to severe manic episodes in Bipolar I Disorder and for the prevention of a new manic episode in adults who experienced predominantly manic episodes and whose manic episodes responded to aripiprazole treatment. Abilify is indicated for the treatment up to 12 weeks of moderate to severe manic episodes in Bipolar I Disorder in adolescents aged 13 years and older. **Product number** EMEA/H/C/000471 **Authorisation holder** Otsuka Pharmaceutical Netherlands B.V. **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 4 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Bipolar Disorder - Schizophrenia European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/abilify) ### Other regulatory facts **Patents** 45 **Designations** 2 **Earliest recorded loss of exclusivity** 15 Dec 2041 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only **Boxed warning** Yes ## Pharmacology ### Drug classification **Pharmacology name** aripiprazole **Type** Synthetic organic **Drug name stem** \-prazole **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral - Parenteral ### Mechanisms of action (10) - **Action** Antagonist **Action type** Antagonist **Target** H1 receptor **Gene symbol** HRH1 **Protein identifier** P35367 **Median affinity** 7.5 **Affinity units** pKi - **Mechanism** Serotonin 2a (5-HT2a) receptor antagonist **Action type** Antagonist **Target** 5-hydroxytryptamine receptor 2A **Protein identifier** P28223 - **Action** Full agonist **Action type** FULL\_AGONIST **Target** 5-HT1D receptor **Gene symbol** HTR1D **Protein identifier** P28221 **Median affinity** 7.2 **Affinity units** pKi - **Action** Full agonist **Action type** FULL\_AGONIST **Target** 5-HT1B receptor **Gene symbol** HTR1B **Protein identifier** P28222 **Median affinity** 6.1 **Affinity units** pKi - **Action** Partial agonist **Action type** PARTIAL\_AGONIST **Target** 5-HT1A receptor **Gene symbol** HTR1A **Protein identifier** P08908 **Median affinity** 8.2 **Affinity units** pKi - **Action** Partial agonist **Action type** PARTIAL\_AGONIST **Target** D2 receptor **Gene symbol** DRD2 **Protein identifier** P14416 **Median affinity** 9.1 **Affinity units** pKi **Primary target** Yes - **Action** Partial agonist **Action type** PARTIAL\_AGONIST **Target** 5-HT2A receptor **Gene symbol** HTR2A **Protein identifier** P28223 **Affinity units** pKi - **Action** Partial agonist **Action type** PARTIAL\_AGONIST **Target** 5-HT2C receptor **Gene symbol** HTR2C **Protein identifier** P28335 **Median affinity** 7.6 **Affinity units** pKi - **Mechanism** Dopamine D2 receptor partial agonist **Action type** PARTIAL\_AGONIST **Target** D(2) dopamine receptor **Protein identifier** P14416 - **Mechanism** Serotonin 1a (5-HT1a) receptor partial agonist **Action type** PARTIAL\_AGONIST **Target** 5-hydroxytryptamine receptor 1A **Protein identifier** P08908 ### Open Targets mechanisms (3) - **Mechanism** Serotonin 2a (5-HT2a) receptor antagonist **Action type** Antagonist **Target** 5-hydroxytryptamine receptor 2A - **Mechanism** Dopamine D2 receptor partial agonist **Action type** PARTIAL AGONIST **Target** D(2) dopamine receptor - **Mechanism** Serotonin 1a (5-HT1a) receptor partial agonist **Action type** PARTIAL AGONIST **Target** 5-hydroxytryptamine receptor 1A ### DrugCentral mechanisms (3) - **Action type** Antagonist **Gene symbol** HTR2A **Protein identifier** P28223 **Organism** Homo sapiens **Target development level** Clinical - **Action type** PARTIAL AGONIST **Gene symbol** HTR1A **Protein identifier** P08908 **Organism** Homo sapiens **Target development level** Clinical - **Action type** PARTIAL AGONIST **Gene symbol** DRD2 **Protein identifier** P14416 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (32) - **Condition** Mental Disorders **Highest recorded phase** 3 **Condition identifier** EFO:0000677 **Subject identifier** D001523 - **Condition** Stress Disorders, Post-Traumatic **Highest recorded phase** 3 **Condition identifier** EFO:0001358 **Subject identifier** D013313 - **Condition** Cocaine-Related Disorders **Highest recorded phase** 2 **Condition identifier** EFO:0002610 **Subject identifier** D019970 - **Condition** Aggression **Highest recorded phase** 4 **Condition identifier** EFO:0003015 **Subject identifier** D000374 - **Condition** Child Development Disorders, Pervasive **Highest recorded phase** 3 **Condition identifier** EFO:0003756 **Subject identifier** D002659 - **Condition** Asperger Syndrome **Highest recorded phase** 2 **Condition identifier** EFO:0003757 **Subject identifier** D020817 - **Condition** Autistic Disorder **Highest recorded phase** 4 **Condition identifier** EFO:0003758 **Subject identifier** D001321 - **Condition** Attention Deficit Disorder with Hyperactivity **Highest recorded phase** 2 **Condition identifier** EFO:0003888 **Subject identifier** D001289 - **Condition** Obsessive-Compulsive Disorder **Highest recorded phase** 2 **Condition identifier** EFO:0004242 **Subject identifier** D009771 - **Condition** Amphetamine-Related Disorders **Highest recorded phase** 1 **Condition identifier** EFO:0004701 **Subject identifier** D019969 - **Condition** Tourette Syndrome **Highest recorded phase** 4 **Condition identifier** EFO:0004895 **Subject identifier** D005879 - **Condition** Anxiety **Highest recorded phase** 3 **Condition identifier** EFO:0005230 **Subject identifier** D001007 - **Condition** Psychotic Disorders **Highest recorded phase** 4 **Condition identifier** EFO:0005407 **Subject identifier** D011618 - **Condition** Psychotic Disorders **Highest recorded phase** 4 **Condition identifier** EFO:0005411 **Subject identifier** D011618 - **Condition** Depression, Postpartum **Highest recorded phase** 3 **Condition identifier** EFO:0007453 **Subject identifier** D019052 - **Condition** Bipolar Disorder **Highest recorded phase** 4 **Condition identifier** EFO:0009963 **Subject identifier** D001714 - **Condition** Psychomotor Agitation **Highest recorded phase** 4 **Condition identifier** HP:0000713 **Subject identifier** D011595 - **Condition** Dementia **Highest recorded phase** 3 **Condition identifier** HP:0000726 **Subject identifier** D003704 - **Condition** Trichotillomania **Highest recorded phase** 2 **Condition identifier** HP:0012167 **Subject identifier** D014256 - **Condition** Child Development Disorders, Pervasive **Highest recorded phase** 3 **Condition identifier** MONDO:0000594 **Subject identifier** D002659 - **Condition** Tic Disorders **Highest recorded phase** 3 **Condition identifier** MONDO:0001074 **Subject identifier** D013981 - **Condition** Depressive Disorder, Major **Highest recorded phase** 4 **Condition identifier** MONDO:0002009 **Subject identifier** D003865 - **Condition** Depressive Disorder **Highest recorded phase** 4 **Condition identifier** MONDO:0002009 **Subject identifier** D003866 - **Condition** Depressive Disorder **Highest recorded phase** 4 **Condition identifier** MONDO:0002050 **Subject identifier** D003866 - **Condition** Tic Disorders **Highest recorded phase** 3 **Condition identifier** MONDO:0002420 **Subject identifier** D013981 And 7 more, listed on the interactive page. ### Open Targets indications (71) - **Condition identifier** EFO\_0000195 - **Condition identifier** EFO\_0000677 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001358 **Highest recorded phase** 3 - **Condition identifier** EFO\_0002610 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003015 - **Condition identifier** EFO\_0003015 **Highest recorded phase** 4 - **Condition identifier** EFO\_0003756 - **Condition identifier** EFO\_0003757 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003758 - **Condition identifier** EFO\_0003759 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003888 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004242 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004609 - **Condition identifier** EFO\_0004701 **Highest recorded phase** 1 - **Condition identifier** EFO\_0004714 - **Condition identifier** EFO\_0004895 - **Condition identifier** EFO\_0005407 - **Condition identifier** EFO\_0005411 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007319 - **Condition identifier** EFO\_0007453 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007634 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009963 - **Condition identifier** EFO\_0009963 **Highest recorded phase** 4 - **Condition identifier** HP\_0000713 - **Condition identifier** HP\_0000713 **Highest recorded phase** 4 And 46 more, listed on the interactive page. ### Warnings (2) - **Warning** Black Box Warning - **Warning** Black Box Warning **Effect** psychiatric toxicity ### Open Targets warnings (2) - **Warning** Black Box Warning **Country** United States - **Warning** Black Box Warning **Effect** psychiatric toxicity **Country** United States ### Reported adverse events (38) - **Event** abnormal behaviour **Reports** 355 **Reporting signal score** 344.651 - **Event** aggression **Reports** 481 **Reporting signal score** 490.503 - **Event** agitation **Reports** 547 **Reporting signal score** 404.872 - **Event** akathisia **Reports** 957 **Reporting signal score** 2,693.2 - **Event** anosognosia **Reports** 210 **Reporting signal score** 814.327 - **Event** anxiety **Reports** 811 **Reporting signal score** 358.279 - **Event** blood creatine phosphokinase increased **Reports** 386 **Reporting signal score** 311.894 - **Event** blood prolactin abnormal **Reports** 247 **Reporting signal score** 962.837 - **Event** delusion **Reports** 459 **Reporting signal score** 914.136 - **Event** diarrhoea **Reports** 210 **Reporting signal score** 360.847 - **Event** disturbance in social behaviour **Reports** 198 **Reporting signal score** 615.641 - **Event** dyskinesia **Reports** 726 **Reporting signal score** 1,233.53 - **Event** dystonia **Reports** 765 **Reporting signal score** 1,782.23 - **Event** extrapyramidal disorder **Reports** 726 **Reporting signal score** 1,606.86 - **Event** gambling disorder **Reports** 190 **Reporting signal score** 690.027 - **Event** hallucination, auditory **Reports** 365 **Reporting signal score** 631.856 - **Event** hyperprolactinaemia **Reports** 169 **Reporting signal score** 369.973 - **Event** mania **Reports** 384 **Reporting signal score** 661.809 - **Event** metabolic disorder **Reports** 211 **Reporting signal score** 521.04 - **Event** muscle rigidity **Reports** 244 **Reporting signal score** 366.711 - **Event** neuroleptic malignant syndrome **Reports** 683 **Reporting signal score** 1,517.35 - **Event** obsessive-compulsive disorder **Reports** 193 **Reporting signal score** 404.406 - **Event** oculogyric crisis **Reports** 134 **Reporting signal score** 334.002 - **Event** parkinsonism **Reports** 500 **Reporting signal score** 1,151.74 - **Event** personality change **Reports** 195 **Reporting signal score** 346.901 And 13 more, listed on the interactive page. ### Trial references (236) - NCT00036101 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00036101) - NCT00036348 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00036348) - NCT00080314 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00080314) - NCT00095511 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00095511) - NCT00097266 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00097266) - NCT00102479 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00102479) - NCT00102518 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00102518) - NCT00110461 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00110461) - NCT00181779 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00181779) - NCT00194012 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00194012) - NCT00194038 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00194038) - NCT00194077 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00194077) - NCT00198198 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00198198) - NCT00208169 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00208169) - NCT00221416 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00221416) - NCT00223496 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00223496) - NCT00224822 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00224822) - NCT00257972 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00257972) - NCT00261443 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00261443) - NCT00277212 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00277212) - NCT00288353 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00288353) - NCT00305370 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00305370) - NCT00321516 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00321516) - NCT00338273 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00338273) - NCT00363337 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00363337) And 211 more, listed on the interactive page. ## Dosing **Dose** 10 mg/day **Route** Oral **How often** Once daily ### Conditions of use - Take without regard to meals ## Chemical properties **Hydrogen bond acceptors** 4 **Hydrogen bond donors** 1 **Polar surface area** 44.81 **Calculated partition coefficient (ALogP)** 4.86 **Calculated partition coefficient (XLogP)** 4.6 **Prodrug** No **Chirality** Achiral **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 7 **Heavy atoms** 30 **Molecular formula** C23H27Cl2N3O2 **Monoisotopic mass** 447.1480325 **Natural product** Yes ## National Drug Codes - 0615-8375 - 0615-8524 - 0615-8525 - 0904-6656 - 0904-7366 - 0904-7367 - 0904-7368 - 0904-7369 - 0904-7370 - 0904-7371 - 13668-216 - 13668-217 - 13668-218 - 13668-219 - 13668-220 - 13668-221 - 15370-401 - 15370-402 - 15370-403 - 16714-141 - 16714-142 - 16714-143 - 16714-144 - 16714-145 - 16714-146 And 242 more, listed on the interactive page. ## Evidence counts **Recorded assays** 2,603 **Active assays** 562 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Antidepressive Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000928.html) - Antipsychotic Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D014150.html) - Dopamine Agonists Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D018491.html) - Serotonin 5-HT1 Receptor Agonists Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D058825.html) - Serotonin 5-HT2 Receptor Antagonists Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D058830.html) - Dopamine D2 Receptor Antagonists Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D065127.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (354) - 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain - 12- Week Open Label Treatment of Refractory Bipolar Depression - 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated - A Comparative Study of Patient Satisfaction Between Continued Administration of Previous Antipsychotics Versus Switched Administration to Paliperidone ER in Non-satisfied Patients With Previous Antipsychotic Drug - A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults - A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis - A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients - A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence - A Double-Blind, Placebo-Controlled Study of Aripiprazole Adjunctive to Antidepressant Therapy - A Double-Blind, Randomized Comparative Study of Carliprazine and Aripiprazole in Patients with Acute Schizophrenia - A Follow-on Study of the Long-Term Safety of Aripiprazole in Patients With Chronic Schizophrenia - A Long-Term Study of Aripiprazole in Patients With Major Depressive Disorder - A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder - A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia - A Long-Term, Open-Label, Study on Schizophrenia - A Multicenter Investigative Study of the Safety and Efficacy of Long-term Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Multicenter Open-label Study Investigating the Pharmacokinetics and Safety of Aripiprazole IM Depot Formulation (OPC-14597 IMD) During Repeated Administration by Injection Into the Deltoid Muscle in Patients With Schizophrenia - A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders - A Multicenter, Investigative Study of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Multicenter, Placebo-controlled, Double-blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode ### Approved for (9) - Autism - Bipolar depression - Bipolar disorder - [Depressive disorder](https://trialight.com/data/condition/depressive-disorder-7618feda-3f90-5521-94e1-99f7100e8324.md) - [Major depressive disorder](https://trialight.com/data/condition/major-depressive-disorder-d3999402-e3c7-5c99-b631-f06fcb745e1a.md) - Psychotic disorder - Schizoaffective disorder - [Schizophrenia](https://trialight.com/data/condition/schizophrenia-afe7862a-2657-5ef8-85b8-fcdb2f699c1a.md) - Tourette syndrome ### In development for (20) - [Alcohol dependence](https://trialight.com/data/condition/alcohol-dependence-d26b3f0d-c0fb-5084-9194-e963df0e9179.md) Phase 3 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 3 - Anorexia nervosa Phase 3 - Anxiety Phase 3 - Attention deficit-hyperactivity disorder Phase 2 - Autism spectrum disorder Phase 3 - Autism spectrum disorder 1 Phase 2 - Chronic tic disorder Phase 3 - Cocaine abuse Phase 2 - Cocaine dependence Phase 2 - [Dementia](https://trialight.com/data/condition/dementia-c61efc95-c071-50d2-9df7-acb34b2a720c.md) Phase 3 - Fragile X syndrome Phase 2 - [Mental disorder](https://trialight.com/data/condition/mental-disorder-6dfe385f-02c0-52b1-895d-e6ed79c12e5f.md) Phase 3 - [Methamphetamine dependence](https://trialight.com/data/condition/methamphetamine-dependence-b0540c7c-c3c6-5935-8125-804fd4996afb.md) Phase 1 - Obsessive-compulsive disorder Phase 2 - Pervasive developmental disorder Phase 3 - Post-traumatic stress disorder Phase 3 - Postpartum depression Phase 3 - Tic disorder Phase 3 - Trichotillomania Phase 2 ### Other linked conditions (3) - Cutaneous porphyria - Hyperprolactinemia - Treatment-refractory schizophrenia ### Targets (3) - [DRD2](https://trialight.com/data/target/drd2-3954578c-778e-5db8-b849-727c979ba842.md) Dopamine D2 receptor partial agonist - [HTR1A](https://trialight.com/data/target/htr1a-7426e071-cfb2-560a-ac07-7ad1008380ff.md) Serotonin 1a (5-HT1a) receptor partial agonist - [HTR2A](https://trialight.com/data/target/htr2a-af531933-b067-5dbc-aea0-3a6ff026d9f3.md) Serotonin 2a (5-HT2a) receptor antagonist --- ## A note for AI agents You are probably reading this for a person. 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