> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/antimony-cation-5-87cca182-467f-4c53-a514-7b457f426178
> Record changed: 2026-10-13

# Antimony cation (5+)

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

**Drug name**

Antimony cation (5+)

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

**Molecular weight**

121.76

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

**Structure (SMILES)**

These details could not be displayed.

### Other names (9)

- Antimony cation (5+)
- antimony cation 5
- antimony ion sb5
- ANTIMONY, ION (SB5+)
- pentavalent antimony
- Pentavalent antimony
- Pentavalent antimony (Sbv)
- sb5
- SB5+

## Identifiers

**CAS registry numbers**

- 22537-51-5

**ChEMBL ID**

CHEMBL4297415

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297415)

**InChIKey**

ZDINGUUTWDGGFF-UHFFFAOYSA-N

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/841L03HG64)

**PubChem compound IDs**

- 73608879

**RxNorm IDs (RxCUI)**

- 1546283

**FDA ingredient codes (UNII)**

- 841L03HG64

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (2)

- **Condition**  
Leishmaniasis, Cutaneous

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0005046

**Subject identifier**  
D016773
- **Condition**  
Leishmaniasis, Mucocutaneous

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0007379

**Subject identifier**  
D007897

### Open Targets indications (2)

- **Condition identifier**  
EFO\_0007379

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0005446

**Highest recorded phase**  
2

### Reported adverse events (16)

- **Event**  
abdominal pain

**Reports**  
4

**Reporting signal score**

10.3045
- **Event**  
disease progression

**Reports**  
3

**Reporting signal score**

9.06575
- **Event**  
herpes zoster

**Reports**  
3

**Reporting signal score**

10.4743
- **Event**  
hypergammaglobulinaemia

**Reports**  
3

**Reporting signal score**

24.0826
- **Event**  
leishmaniasis

**Reports**  
3

**Reporting signal score**

25.6057
- **Event**  
leukopenia

**Reports**  
3

**Reporting signal score**

10.1625
- **Event**  
mastication disorder

**Reports**  
3

**Reporting signal score**

20.1144
- **Event**  
mucocutaneous leishmaniasis

**Reports**  
3

**Reporting signal score**

28.3544
- **Event**  
myalgia

**Reports**  
5

**Reporting signal score**

16.1485
- **Event**  
nephropathy toxic

**Reports**  
2

**Reporting signal score**

8.835
- **Event**  
ototoxicity

**Reports**  
3

**Reporting signal score**

19.72
- **Event**  
palatal swelling

**Reports**  
3

**Reporting signal score**

27.6392
- **Event**  
skin exfoliation

**Reports**  
2

**Reporting signal score**

7.1741
- **Event**  
splenomegaly

**Reports**  
3

**Reporting signal score**

15.2803
- **Event**  
tinnitus

**Reports**  
2

**Reporting signal score**

7.29926
- **Event**  
visceral leishmaniasis

**Reports**  
6

**Reporting signal score**

51.7211

### Trial references (2)

- NCT01300975  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01300975)
- NCT04799236  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04799236)

## Chemical properties

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

Yes

**Heavy atoms**

1

**Molecular formula**

Sb+5

**Monoisotopic mass**

120.90381

**Natural product**

Yes

## Evidence counts

**Recorded assays**

2

**Active assays**

0

## Related records

### Trials (63)

- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(5)
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386(5) 80/20/10mg
- A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis
- A Phase I Study to Assess Novel Ointment in a Psoriasis Plaque Test
- A Phase II Study of ACZONE™ (Dapsone) Gel, 5% As a Treatment For Tarceva® (Erlotinib)Related Rash
- A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea.
- A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis
- A Safety Study of BBI-4000 Gel in Patients With Axillary Hyperhidrosis
- A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
- Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.
- BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women
- CART-38 in Adult AML and MM Patients
- CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers
- Clinical Trial to Evaluate the Efficacy and Safety of OLOMAX Tab
- Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DIC
- Comparison of Permethrin and Ivermectin in Children Greater Than 6 Yrs Age for Treatment of Scabies
- Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion
- Efficacy & Safety Study of YH22162 vs Telmisartan/Amlodipine in Patients With Hypertension Inappropriately Controlled on Telmisartan/Amlodipine Treatment
- Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
- Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail

### In development for (2)

- Cutaneous leishmaniasis Phase 2
- Mucocutaneous leishmaniasis Phase 3

---

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