AMG-650
Highest phase reached
Phase 1
Drug type
Small molecule
- Listing at source
- Listed
- Highest phase reached
- Phase 1
- Drug type
- Small molecule
- Drug name
- AMG-650
- Molecular weight
- 564.66
- Structure (SMILES)
- Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1
- amg 650
- Amg 650
- AMG 650
- Amg-650
- amg650
- AMG650
- sovilnesib
- Sovilnesib
- sovilnesib [INN]
- Sovilnesib [WHO-DD]
- sovilnesib inn
- sovilnesib who dd
- CAS registry numbers
- 2410796-79-9
- ChEMBL ID
- CHEMBL5084301
- InChIKey
- KBDGEJDIHZDPHN-UHFFFAOYSA-N
- PubChem compound IDs
- 148163435
- FDA ingredient codes (UNII)
- OP393M4H32
- First in class
- No
- Orphan designation
- No
- Pharmacology name
- AMG650
- Type
- Synthetic organic
- Hydrogen bond acceptors
- 8
- Hydrogen bond donors
- 3
- Polar surface area
- 127.76
- Calculated partition coefficient (ALogP)
- 3.39
- Calculated partition coefficient (XLogP)
- 3.8
- Prodrug
- No
- Chirality
- Achiral
- Inorganic
- No
- Rule-of-five violations
- 1
- Rotatable bonds
- 8
- Heavy atoms
- 39
- Molecular formula
- C26H34F2N6O4S
- Monoisotopic mass
- 564.23303108
- Natural product
- No
- Recorded assays
- 129
- Active assays
- 37
Active assay types
- Confirmatory
Related records
Trials (2)
- A Study of Sovilnesib in Subjects With Ovarian Cancer
- Study of AMG 650 in Adult Participants With Advanced Solid Tumors