> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/alnuctamab-4489c89d-75f0-45e1-a898-dacda22f155a
> Record changed: 2026-10-13

# Alnuctamab

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

Drug type

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

## Names and chemistry

**Drug type**

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

**Drug name**

Alnuctamab

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

### Other names (10)

- alnuctamab
- Alnuctamab
- alnuctamab \[INN\]
- ALNUCTAMAB \[USAN\]
- Alnuctamab \[WHO-DD\]
- alnuctamab inn
- alnuctamab usan
- alnuctamab who dd
- immunoglobulin g1 kappa lambda with domain crossover anti homo sapiens tnfrsf17 tnf receptor superfamily member 17 tumor necrosis factor receptor superfamily member 17 b cell maturation antigen bcma bcm tnfrsf13a cd269 and anti homo sapiens cd3e cd3 epsilon leu 4 monoclonal antibody bispecific trivalent
- IMMUNOGLOBULIN G1-KAPPA/LAMBDA WITH DOMAIN CROSSOVER, ANTI-(HOMO SAPIENS TNFRSF17 (TNF RECEPTOR SUPERFAMILY MEMBER 17, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 17, B CELL MATURATION ANTIGEN, BCMA, BCM, TNFRSF13A, CD269)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY, BISPECIFIC, TRIVALENT

## Identifiers

**CAS registry numbers**

- 2296827-07-9

**ChEMBL ID**

CHEMBL6068570

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068570)

**FDA ingredient codes (UNII)**

- 7OSV6M6T4D

## Regulatory information

### Other regulatory facts

**Patents**

0

**Designations**

1

**First in class**

No

**Fast track**

No

**Breakthrough designation**

No

**Orphan designation**

No

**Priority review**

No

**Orphan exclusivity**

No

**Accelerated approval**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-mab

### Investigated indications

- **Condition**  
Multiple Myeloma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0001378

**Subject identifier**  
D009101

### Open Targets indications (3)

- **Condition identifier**  
EFO\_0001378

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0007915

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0009693

**Highest recorded phase**  
3

### Trial references (3)

- NCT06121843  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06121843)
- NCT06163898  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06163898)
- NCT06232707  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06232707)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (4)

- A Study to Evaluate Alnuctamab in Combination With Mezigdomide in Participants With Relapsed and/or Refractory Multiple Myeloma
- A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
- [A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma](https://trialight.com/data/trial/a-study-to-evaluate-the-safety-effectiveness-and-tolerable-bf2618cc-f052-43c0-a005-bd672213d933.md)
- Alnuctamab for Refractory SLE (LATTE Study)

### In development for (2)

- [Plasma cell myeloma](https://trialight.com/data/condition/plasma-cell-myeloma-37186689-2591-5775-9042-2f2bf046a2b5.md) Phase 3
- [Systemic lupus erythematosus](https://trialight.com/data/condition/systemic-lupus-erythematosus-6c9d074f-cc5f-588b-bf0c-6338d30c6eac.md) Phase 1

---

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