> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/albumin-human-95414b67-0d38-49d4-91b2-27b1c6c17389 > Record changed: 2026-10-13 # Albumin human Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) Drug type Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) First approval year 1997 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) ## Development status **First approval year** 1997 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) ## Names and chemistry **Drug type** Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) **Drug name** Albumin human Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) ### Brand names (8) - albumin human component of abi 009 - Albumin human component of abi-009 - albuminar 5 - Albuminar-5 - buminate - Buminate - plasbumin - Plasbumin ### Other names (86) - abi 009 component albumin human - ABI-009 COMPONENT ALBUMIN HUMAN - adebrelimab albumin bound paclitaxel cisplatin - adebrelimab plus albumin bound paclitaxel carboplatin and recaticimab - albumin - Albumin - ALBUMIN - Albumin (5% serum-protein solution containing immunoglobulins) - Albumin (bovine) - Albumin (human) - ALBUMIN \[VANDF\] - albumin blood - albumin bound paclitaxel - Albumin bound paclitaxel - Albumin Bound Paclitaxel - albumin bovine - Albumin bovine - albumin human - Albumin human - Albumin Human - ALBUMIN HUMAN \[II\] - ALBUMIN HUMAN \[ORANGE BOOK\] - ALBUMIN HUMAN \[USP MONOGRAPH\] - Albumin human \[WHO-DD\] - albumin human ii And 61 more, listed on the interactive page. ## Identifiers **ATC classification codes** - B05AA01 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) **CAS registry numbers** - 9048-46-8 **ChEMBL ID** CHEMBL1201451 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201451) **FDA ingredient codes (UNII)** - ZIF514RVZR ### RxNorm IDs (RxCUI) (2) - 828529 - 1370439 ## Regulatory information ### United States **Applicant** GE HEALTHCARE **Approval date** 31 Dec 1997 **Application number** NDA020899 ### Other regulatory facts **Patents** 0 **Designations** 1 **Earliest recorded loss of exclusivity** 9 May 2028 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification #### Administration routes - Parenteral ### Mechanisms of action - **Mechanism** Bilirubin sequestering agent **Action type** SEQUESTERING\_AGENT **Target** Bilirubin ### Investigated indications (48) - **Condition** Carcinoma, Squamous Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000181 **Subject identifier** D002294 - **Condition** Carcinoma, Hepatocellular **Highest recorded phase** 3 **Condition identifier** EFO:0000182 **Subject identifier** D006528 - **Condition** Squamous Cell Carcinoma of Head and Neck **Highest recorded phase** 3 **Condition identifier** EFO:0000199 **Subject identifier** D000077195 - **Condition** Pulmonary Disease, Chronic Obstructive **Highest recorded phase** 3 **Condition identifier** EFO:0000341 **Subject identifier** D029424 - **Condition** Stomach Neoplasms **Highest recorded phase** 3 **Condition identifier** EFO:0000503 **Subject identifier** D013274 - **Condition** Adenocarcinoma of Lung **Highest recorded phase** 2 **Condition identifier** EFO:0000571 **Subject identifier** D000077192 - **Condition** Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Subarachnoid Hemorrhage **Highest recorded phase** 1 **Condition identifier** EFO:0000713 **Subject identifier** D013345 - **Condition** Scleroderma, Systemic **Highest recorded phase** 2 **Condition identifier** EFO:0000717 **Subject identifier** D012595 - **Condition** Liver Cirrhosis **Highest recorded phase** 3 **Condition identifier** EFO:0001422 **Subject identifier** D008103 - **Condition** Pancreatic Neoplasms **Highest recorded phase** 3 **Condition identifier** EFO:0002618 **Subject identifier** D010190 - **Condition** Kidney Diseases **Highest recorded phase** 2 **Condition identifier** EFO:0003086 **Subject identifier** D007674 - **Condition** Pneumonia **Highest recorded phase** 2 **Condition identifier** EFO:0003106 **Subject identifier** D011014 - **Condition** Respiratory Distress Syndrome **Highest recorded phase** 4 **Condition identifier** EFO:0003818 **Subject identifier** D012128 - **Condition** Multiple Sclerosis, Relapsing-Remitting **Highest recorded phase** 2 **Condition identifier** EFO:0003929 **Subject identifier** D020529 - **Condition** Hypotension, Orthostatic **Highest recorded phase** 1 **Condition identifier** EFO:0005252 **Subject identifier** D007024 - **Condition** Cerebral Hemorrhage **Highest recorded phase** 2 **Condition identifier** EFO:0005669 **Subject identifier** D002543 - **Condition** Esophageal Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0005922 **Subject identifier** D004938 - **Condition** Shock, Septic **Highest recorded phase** 3 **Condition identifier** EFO:0006834 **Subject identifier** D012772 - **Condition** Edema **Highest recorded phase** 3 **Condition identifier** EFO:0009373 **Subject identifier** D004487 - **Condition** Craniocerebral Trauma **Highest recorded phase** 2 **Condition identifier** EFO:0009505 **Subject identifier** D006259 - **Condition** Burns **Highest recorded phase** 2 **Condition identifier** EFO:0009516 **Subject identifier** D002056 - **Condition** Macular Degeneration **Highest recorded phase** 2 **Condition identifier** EFO:0009606 **Subject identifier** D008268 - **Condition** Central Nervous System Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:1000158 **Subject identifier** D016543 - **Condition** Pancreatic Neoplasms **Highest recorded phase** 3 **Condition identifier** EFO:1000359 **Subject identifier** D010190 And 23 more, listed on the interactive page. ### Open Targets indications (86) - **Condition identifier** EFO\_0000182 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000503 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000616 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000713 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000717 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001422 **Highest recorded phase** 3 - **Condition identifier** EFO\_0002618 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003086 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003106 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003818 - **Condition identifier** EFO\_0004255 - **Condition identifier** EFO\_0005252 - **Condition identifier** EFO\_0005669 **Highest recorded phase** 2 - **Condition identifier** EFO\_0005922 **Highest recorded phase** 2 - **Condition identifier** EFO\_0006834 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007949 - **Condition identifier** EFO\_0007949 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009373 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009505 - **Condition identifier** EFO\_0009505 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009516 - **Condition identifier** EFO\_0009516 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009606 **Highest recorded phase** 2 - **Condition identifier** EFO\_0020910 - **Condition identifier** EFO\_0020910 **Highest recorded phase** 4 And 61 more, listed on the interactive page. ### Reported adverse events (60) - **Event** acute kidney injury **Reports** 54 **Reporting signal score** 67.7683 - **Event** allergic transfusion reaction **Reports** 2 **Reporting signal score** 9.56061 - **Event** anaphylactic reaction **Reports** 36 **Reporting signal score** 57.9346 - **Event** anaphylactic shock **Reports** 15 **Reporting signal score** 24.3797 - **Event** anaphylactoid reaction **Reports** 7 **Reporting signal score** 16.087 - **Event** arthralgia **Reports** 1 **Reporting signal score** 9.29281 - **Event** atrial septal defect **Reports** 7 **Reporting signal score** 11.9439 - **Event** blood pressure decreased **Reports** 20 **Reporting signal score** 25.6952 - **Event** body temperature increased **Reports** 7 **Reporting signal score** 8.62398 - **Event** brain oedema **Reports** 9 **Reporting signal score** 20.3737 - **Event** bronchopulmonary dysplasia **Reports** 5 **Reporting signal score** 18.4847 - **Event** chills **Reports** 32 **Reporting signal score** 37.3215 - **Event** clostridium test positive **Reports** 10 **Reporting signal score** 38.174 - **Event** diffuse large b-cell lymphoma refractory **Reports** 3 **Reporting signal score** 11.2394 - **Event** drug resistance **Reports** 9 **Reporting signal score** 9.73471 - **Event** dyspnoea **Reports** 42 **Reporting signal score** 9.99732 - **Event** enterococcus test positive **Reports** 9 **Reporting signal score** 42.0537 - **Event** febrile nonhaemolytic transfusion reaction **Reports** 2 **Reporting signal score** 9.15695 - **Event** foetal death **Reports** 10 **Reporting signal score** 29.6122 - **Event** foetal growth restriction **Reports** 9 **Reporting signal score** 20.8708 - **Event** haematochezia **Reports** 10 **Reporting signal score** 8.99429 - **Event** haemodynamic instability **Reports** 6 **Reporting signal score** 12.1533 - **Event** haemorrhage **Reports** 15 **Reporting signal score** 10.6537 - **Event** heart rate increased **Reports** 18 **Reporting signal score** 20.2365 - **Event** hepatitis c antibody positive **Reports** 5 **Reporting signal score** 23.8525 And 35 more, listed on the interactive page. ### Trial references (72) - NCT00124228 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00124228) - NCT00428506 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00428506) - NCT05895136 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05895136) - NCT00152685 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00152685) - NCT00220740 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00220740) - NCT00220779 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00220779) - NCT00220805 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00220805) - NCT00235495 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00235495) - NCT06113848 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06113848) - NCT06172387 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06172387) - NCT00263887 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00263887) - NCT00722475 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00722475) - NCT00742417 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00742417) - NCT01524887 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01524887) - NCT01561053 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01561053) - NCT00769028 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00769028) - NCT00773110 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00773110) - NCT00852800 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00852800) - NCT00990509 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00990509) - NCT01420744 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01420744) - NCT01684462 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01684462) - NCT01747408 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01747408) - NCT02055872 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02055872) - NCT02172937 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02172937) - NCT02956122 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02956122) And 47 more, listed on the interactive page. ## Dosing **Dose** 25g, 50-75g, 50-100g, 10-50g, 100mL **Route** Intravenous **How often** As specified per indication (e.g., daily, every 4-12 hours, over 4 hours, every 8 hours, for 3 days) ### Conditions of use (5) - Discard unused material - Do not dilute with sterile water for injection - Do not start > 4 hours after entry - Inspect visually before administration - Warm to room temperature if large volumes ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## National Drug Codes - 64208-2510 - 64208-2512 ## Related records ### Trials (464) - "Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function" - 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension - 4 Courses vs 2 Courses of Pembrolizumab Combined With Carboplatin and Albumin-binding Paclitaxel of Neoadjuvant Therapy in HNSCC - A Clinical Comparison of Connective Tissue Graft and Alb-PRF for Rebuilding Interdental Papilla - A Clinical Study of Albumin-bound Paclitaxel/Granulocyte-based Therapy for Recurrent/Metastatic Breast Cancer - A Clinical Study of Docetaxel for Injection (Albumin-bound) in Patients With Gastric Cancer - A Clinical Study to Evaluate Efficacy and Safety of HLX10 Combined With Albumin-Bound Paclitaxel in Patients With Advanced Cervical Cancer Who Have Progressive Disease or Intolerable Toxicity After First-Line Standard Chemotherapy - A Clinical Trial to Evaluate the Efficacy and Safety of TQB2102 for Injection Versus Investigator-Selected Chemotherapy in HER2 Low-Expressing Recurrent/Metastatic Breast Cancer - A Neoadjuvant Study of Sintilimab Plus Platinum Doublet Chemotherapy in IIIA(N2) Stage NSCLC - A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial). - A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD - A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer - A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors - A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer - A Pilot Study of Hemin Therapy for Gastroparesis (Diabetes Mellitus) - A Prospective, Single-arm, Exploratory Clinical Study of Sintilimab Injection in Combination With Paclitaxel (Albumin-bound) and Gemcitabine in Translational Therapy in Patients With Unresectable Locally Advanced Pancreatic Cancer. - A Random, Non-controlled, Open Clinical Study of Apatinib Mesylate Combined With Albumin-bound Paclitaxel ± Adebrelimab in Treating Advanced Second-line Gastric Cancer - A Sequential Trial of Low-Dose Radiotherapy Followed by Concurrent Immunotherapy, Systemic Chemotherapy, and Intraperitoneal Perfusion in Gastric Cancer With Peritoneal Carcinomatosis - A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced, Recurrent, or Metastatic HR+/HER2- Breast Cancer After Failure of Prior Endocrine Therapy(PANKU-Breast03) - A Study Investigating Intravenous Human Normal Immune Globulin 10% in Adults With Stiff Person Syndrome ### Approved for (2) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Nephrosis ### In development for (40) - Adrenoleukodystrophy Phase 2 - Adrenomyeloneuropathy Phase 2 - Alpha 1-antitrypsin deficiency Phase 2 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 3 - [Amyotrophic lateral sclerosis](https://trialight.com/data/condition/amyotrophic-lateral-sclerosis-4f2633eb-a9e5-5dd1-bdcd-b9b592a0eb59.md) Phase 2 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 3 - Burn Phase 2 - [Central nervous system neoplasm](https://trialight.com/data/condition/central-nervous-system-neoplasm-bd35c306-06e5-549c-a882-45bdfbcbb7d8.md) Phase 1 - Cerebral infarction Phase 2 - Chronic inflammatory demyelinating polyradiculoneuropathy Phase 3 - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) Phase 3 - [Cirrhosis of liver](https://trialight.com/data/condition/cirrhosis-of-liver-d90e4a84-9e82-54fc-a553-1e42086e8382.md) Phase 3 - [Endometrial cancer](https://trialight.com/data/condition/endometrial-cancer-4da2a0bc-7943-502b-a698-cc2beccbed8c.md) Phase 3 - [Esophageal squamous cell carcinoma](https://trialight.com/data/condition/esophageal-squamous-cell-carcinoma-c10bd9c9-02f9-5805-8008-b021f4604e7a.md) Phase 2 - Exocrine pancreatic carcinoma Phase 3 - [Gastric adenocarcinoma](https://trialight.com/data/condition/gastric-adenocarcinoma-6bb74a55-7ba6-53e3-a113-22296a84d6ae.md) Phase 3 - [Gastric cancer](https://trialight.com/data/condition/gastric-cancer-3c1e2785-2672-5b3e-afce-9335f684c159.md) Phase 3 - [Gastroesophageal junction adenocarcinoma](https://trialight.com/data/condition/gastroesophageal-junction-adenocarcinoma-de7e280e-cbd1-5266-a5dd-dda00261a706.md) Phase 2 - Graft versus host disease Phase 2 - Habitual spontaneous abortion Phase 3 ### Other linked conditions (2) - Anemia - Nephrotic syndrome --- ## A note for AI agents You are probably reading this for a person. 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